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The map label for this gene is hslV

Identifier: 114798299

GI number: 114798299

Start: 2110242

End: 2110799

Strand: Direct

Name: hslV

Synonym: HNE_2033

Alternate gene names: 114798299

Gene position: 2110242-2110799 (Clockwise)

Preceding gene: 114797860

Following gene: 114800330

Centisome position: 56.96

GC content: 61.11

Gene sequence:

>558_bases
ATGACCAACCCTCAGGATTCAAAGGCCATCTGGCACGGAACGACGGTGCTCGCCGTGCGCAAGAATGGCAAACTCGTGAT
GCTCAGCGACGGCCAGGTGTCGATGGGTCAGACCATAATGAAGGGCAATGCGCGCAAGGTGCGCCGGATTGCGGGCGGGC
AGATTCTCGCCGGATTCGCCGGGGCGACGGCCGATGCATTTACCCTGTTCGAGCGGCTGGAGGCGAAGCTGGAACGCTTC
CCCGACCAGTTGCAGCGGGCGGCGGTGGAACTGGCCAAGGACTGGCGGACAGAGAAATACCTCCAGAAACTGGAAGCTTT
GCTGATCGTGGCTGACAAGCACAGCACGCTGGTGATCACCGGCGCGGGCGATGTGCTGGAGCCCGAACATCATGTTGTGT
CGATCGGGTCTGGCGGGAACTATGCCCTCGCCGCGGCGCGCGGCCTCTATGATTATGAGGAGGACGCCGAAACGATCGGA
CGCAAGGCGATGCAGATTGCTGCCGACATCTGCGTCTACACCAACGGCCATTTCAGCGTGGAAACCCTGGAAATCTGA

Upstream 100 bases:

>100_bases
AAATAGAAGAAGGCCGCGACAGTTATGTGACAATCTTCTGTATTTCCTGACGCAGGGGCCCTCTATTGCGTGGGCGCGTC
AAAGACGCCATGTGTTCGCC

Downstream 100 bases:

>100_bases
GGCCGGCGCCGGAGCGGATAACGCTCCAAGGGCGGCGCCCATAAGCTCCATTCAGAGCGGCCATCATAAGGCCCCCACCA
GATACAAGATGAGATCGATT

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTNPQDSKAIWHGTTVLAVRKNGKLVMLSDGQVSMGQTIMKGNARKVRRIAGGQILAGFAGATADAFTLFERLEAKLERF
PDQLQRAAVELAKDWRTEKYLQKLEALLIVADKHSTLVITGAGDVLEPEHHVVSIGSGGNYALAAARGLYDYEEDAETIG
RKAMQIAADICVYTNGHFSVETLEI

Sequences:

>Translated_185_residues
MTNPQDSKAIWHGTTVLAVRKNGKLVMLSDGQVSMGQTIMKGNARKVRRIAGGQILAGFAGATADAFTLFERLEAKLERF
PDQLQRAAVELAKDWRTEKYLQKLEALLIVADKHSTLVITGAGDVLEPEHHVVSIGSGGNYALAAARGLYDYEEDAETIG
RKAMQIAADICVYTNGHFSVETLEI
>Mature_184_residues
TNPQDSKAIWHGTTVLAVRKNGKLVMLSDGQVSMGQTIMKGNARKVRRIAGGQILAGFAGATADAFTLFERLEAKLERFP
DQLQRAAVELAKDWRTEKYLQKLEALLIVADKHSTLVITGAGDVLEPEHHVVSIGSGGNYALAAARGLYDYEEDAETIGR
KAMQIAADICVYTNGHFSVETLEI

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=56.140350877193, Blast_Score=196, Evalue=8e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_HYPNA (Q0C0L2)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760731.1
- ProteinModelPortal:   Q0C0L2
- SMR:   Q0C0L2
- STRING:   Q0C0L2
- MEROPS:   T01.006
- GeneID:   4289463
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2033
- NMPDR:   fig|228405.5.peg.1958
- TIGR:   HNE_2033
- eggNOG:   COG5405
- HOGENOM:   HBG288822
- OMA:   AADICVY
- PhylomeDB:   Q0C0L2
- ProtClustDB:   PRK05456
- BioCyc:   HNEP81032:HNE_2033-MONOMER
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 20144; Mature: 20013

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: ACT_SITE 14-14

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPQDSKAIWHGTTVLAVRKNGKLVMLSDGQVSMGQTIMKGNARKVRRIAGGQILAGFA
CCCCCCCCEEEECEEEEEEECCCCEEEEECCCCCCCHHHHCCCHHHHHHHCCCEEEEECC
GATADAFTLFERLEAKLERFPDQLQRAAVELAKDWRTEKYLQKLEALLIVADKHSTLVIT
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCEEEEE
GAGDVLEPEHHVVSIGSGGNYALAAARGLYDYEEDAETIGRKAMQIAADICVYTNGHFSV
CCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCEEE
ETLEI
EEECC
>Mature Secondary Structure 
TNPQDSKAIWHGTTVLAVRKNGKLVMLSDGQVSMGQTIMKGNARKVRRIAGGQILAGFA
CCCCCCCEEEECEEEEEEECCCCEEEEECCCCCCCHHHHCCCHHHHHHHCCCEEEEECC
GATADAFTLFERLEAKLERFPDQLQRAAVELAKDWRTEKYLQKLEALLIVADKHSTLVIT
CCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCCEEEEE
GAGDVLEPEHHVVSIGSGGNYALAAARGLYDYEEDAETIGRKAMQIAADICVYTNGHFSV
CCCCCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCEEE
ETLEI
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA