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The map label for this gene is ribD [H]

Identifier: 114798296

GI number: 114798296

Start: 2132288

End: 2132941

Strand: Reverse

Name: ribD [H]

Synonym: HNE_2058

Alternate gene names: 114798296

Gene position: 2132941-2132288 (Counterclockwise)

Preceding gene: 114797364

Following gene: 114798806

Centisome position: 57.57

GC content: 68.81

Gene sequence:

>654_bases
ATGAAAAACCTCCGCATCACCCTCAAGATTGCGTCCTCACTGGATGGGCGCATCGCGCTGGCCGATGGCACCAGCCAGTG
GATCACCTCCAGCGCGTCGCGCGCCCGCGGCCACCAGATGCGCGCTGAAAACGACGCCATCATGGTCGGCATCGGCACAG
CCCTGGCGGACGATCCGCTGCTCACCGCCCGCACCGTGCCGCTCCCGGCCAAACAACCCGTCCGCATCGTCGCCGATTCC
AACGCCCGCCTGCCCACCGCCTCGCGCCTCGCCAGCTCCACCGATCTTGGCCGCGTTGTCGCCGTCACGGCGGGGCAGGG
CAGCGACGCCCTCGCCGCTGCCGGGGTCGACATCTGGCGCTGCGGCAACGGTGTTCGCATGGACGCGGGCGAATTCGTCC
GCCGCGCCGAAGCCGAGGGTCTGCGCACGCTGCTCATCGAAGGGGGCAGCACGCTGGCCGCCAGCTTCATGCGCGCCGGC
CTCGTGGACGAGATCGCCTGGTTTCGCGCCCCCATCCTGATCGGCGGCGATGGCTTGCCCGCCCTCGGGGCGCTGGGCCT
GTCAGACCTGAAATCTGCGGCACGCTGGCGCCCTGTCGCGACGGAACGGATTGGGGATGACGTCCTCGATACTTATGTTC
GATCTGAGCAATAG

Upstream 100 bases:

>100_bases
GCTACGCCAGCGTCTATCGCGACTTCAAAGACCCGAGCGATTTCGCCCAGTTCATCGAAAAAGCCGCCCTCGAAGACGAA
GACGACGACGCGGACGGGAA

Downstream 100 bases:

>100_bases
GCACCCAGGATAAGAACCATGTTCACAGGTCTCGTCACCGATGTCGGCACTGTCCGCAAGGCAGAGCACCGCAACGGCCT
CACCCGGTTTGAGGTCGAAA

Product: riboflavin biosynthesis protein RibD domain-containing protein

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MKNLRITLKIASSLDGRIALADGTSQWITSSASRARGHQMRAENDAIMVGIGTALADDPLLTARTVPLPAKQPVRIVADS
NARLPTASRLASSTDLGRVVAVTAGQGSDALAAAGVDIWRCGNGVRMDAGEFVRRAEAEGLRTLLIEGGSTLAASFMRAG
LVDEIAWFRAPILIGGDGLPALGALGLSDLKSAARWRPVATERIGDDVLDTYVRSEQ

Sequences:

>Translated_217_residues
MKNLRITLKIASSLDGRIALADGTSQWITSSASRARGHQMRAENDAIMVGIGTALADDPLLTARTVPLPAKQPVRIVADS
NARLPTASRLASSTDLGRVVAVTAGQGSDALAAAGVDIWRCGNGVRMDAGEFVRRAEAEGLRTLLIEGGSTLAASFMRAG
LVDEIAWFRAPILIGGDGLPALGALGLSDLKSAARWRPVATERIGDDVLDTYVRSEQ
>Mature_217_residues
MKNLRITLKIASSLDGRIALADGTSQWITSSASRARGHQMRAENDAIMVGIGTALADDPLLTARTVPLPAKQPVRIVADS
NARLPTASRLASSTDLGRVVAVTAGQGSDALAAAGVDIWRCGNGVRMDAGEFVRRAEAEGLRTLLIEGGSTLAASFMRAG
LVDEIAWFRAPILIGGDGLPALGALGLSDLKSAARWRPVATERIGDDVLDTYVRSEQ

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=214, Percent_Identity=31.3084112149533, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 22759; Mature: 22759

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLRITLKIASSLDGRIALADGTSQWITSSASRARGHQMRAENDAIMVGIGTALADDPL
CCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHCCCCC
LTARTVPLPAKQPVRIVADSNARLPTASRLASSTDLGRVVAVTAGQGSDALAAAGVDIWR
EEEECCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHCCCEEEE
CGNGVRMDAGEFVRRAEAEGLRTLLIEGGSTLAASFMRAGLVDEIAWFRAPILIGGDGLP
CCCCCEECHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
ALGALGLSDLKSAARWRPVATERIGDDVLDTYVRSEQ
HHHHCCHHHHHHHHHCCCCHHHHHCHHHHHHHHHCCC
>Mature Secondary Structure
MKNLRITLKIASSLDGRIALADGTSQWITSSASRARGHQMRAENDAIMVGIGTALADDPL
CCCEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHCCCCC
LTARTVPLPAKQPVRIVADSNARLPTASRLASSTDLGRVVAVTAGQGSDALAAAGVDIWR
EEEECCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCEEEEEECCCCCCCHHHCCCEEEE
CGNGVRMDAGEFVRRAEAEGLRTLLIEGGSTLAASFMRAGLVDEIAWFRAPILIGGDGLP
CCCCCEECHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
ALGALGLSDLKSAARWRPVATERIGDDVLDTYVRSEQ
HHHHCCHHHHHHHHHCCCCHHHHHCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]