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The map label for this gene is nrdR

Identifier: 114797364

GI number: 114797364

Start: 2132938

End: 2133417

Strand: Reverse

Name: nrdR

Synonym: HNE_2059

Alternate gene names: 114797364

Gene position: 2133417-2132938 (Counterclockwise)

Preceding gene: 114799314

Following gene: 114798296

Centisome position: 57.58

GC content: 61.04

Gene sequence:

>480_bases
TTGCGCTGTCCATTCTGCGGTTCTGACAATACATCCGTAAAAGACAGCCGCGCCGCTGAAGACGATACCGCTGTGCGCCG
CCGCCGCGTCTGTGAAAGCTGCGGCGCCCGCTTCACCACCTTCGAGCGTGTGCAGCTGCGCGAAATCATCGTCGTCAAAC
GCGATGGCAAACGCAGCCTGTTTGACCGGGAAAAACTGCAACGCTCCATCCTCATCGCCCTGCGCAAACGCCCAGTGGAC
CGAGACCGGATCGACCAGATGGTCTCCGGCATCGTCCGCAAGCTGGAAAGCGGCGGGGAAACCGAGGTGCCCTCCTCAGA
GGTCGGCGAGTTGGTGATGGAAGCGCTCAAGCGCGTCGATCCCGTCGGCTATGTCCGCTACGCCAGCGTCTATCGCGACT
TCAAAGACCCGAGCGATTTCGCCCAGTTCATCGAAAAAGCCGCCCTCGAAGACGAAGACGACGACGCGGACGGGAAATGA

Upstream 100 bases:

>100_bases
CAATGGCAACAGCGACGCGGTTGAAGCCCGCGTCCGCGAAGAGGTGAAGGCGCTCACGGCGCGTTTCCCCATCTATGAGG
GGCTGGGGGGCTGATCGGCT

Downstream 100 bases:

>100_bases
AAAACCTCCGCATCACCCTCAAGATTGCGTCCTCACTGGATGGGCGCATCGCGCTGGCCGATGGCACCAGCCAGTGGATC
ACCTCCAGCGCGTCGCGCGC

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRCPFCGSDNTSVKDSRAAEDDTAVRRRRVCESCGARFTTFERVQLREIIVVKRDGKRSLFDREKLQRSILIALRKRPVD
RDRIDQMVSGIVRKLESGGETEVPSSEVGELVMEALKRVDPVGYVRYASVYRDFKDPSDFAQFIEKAALEDEDDDADGK

Sequences:

>Translated_159_residues
MRCPFCGSDNTSVKDSRAAEDDTAVRRRRVCESCGARFTTFERVQLREIIVVKRDGKRSLFDREKLQRSILIALRKRPVD
RDRIDQMVSGIVRKLESGGETEVPSSEVGELVMEALKRVDPVGYVRYASVYRDFKDPSDFAQFIEKAALEDEDDDADGK
>Mature_159_residues
MRCPFCGSDNTSVKDSRAAEDDTAVRRRRVCESCGARFTTFERVQLREIIVVKRDGKRSLFDREKLQRSILIALRKRPVD
RDRIDQMVSGIVRKLESGGETEVPSSEVGELVMEALKRVDPVGYVRYASVYRDFKDPSDFAQFIEKAALEDEDDDADGK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=151, Percent_Identity=47.682119205298, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_HYPNA (Q0C0I6)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760757.1
- STRING:   Q0C0I6
- GeneID:   4287295
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2059
- NMPDR:   fig|228405.5.peg.1984
- TIGR:   HNE_2059
- eggNOG:   COG1327
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- PhylomeDB:   Q0C0I6
- ProtClustDB:   CLSK2531653
- BioCyc:   HNEP81032:HNE_2059-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 18140; Mature: 18140

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGSDNTSVKDSRAAEDDTAVRRRRVCESCGARFTTFERVQLREIIVVKRDGKRSL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHH
FDREKLQRSILIALRKRPVDRDRIDQMVSGIVRKLESGGETEVPSSEVGELVMEALKRVD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
PVGYVRYASVYRDFKDPSDFAQFIEKAALEDEDDDADGK
CHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRCPFCGSDNTSVKDSRAAEDDTAVRRRRVCESCGARFTTFERVQLREIIVVKRDGKRSL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHH
FDREKLQRSILIALRKRPVDRDRIDQMVSGIVRKLESGGETEVPSSEVGELVMEALKRVD
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCC
PVGYVRYASVYRDFKDPSDFAQFIEKAALEDEDDDADGK
CHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA