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The map label for this gene is engA

Identifier: 114798294

GI number: 114798294

Start: 783855

End: 785387

Strand: Direct

Name: engA

Synonym: HNE_0774

Alternate gene names: 114798294

Gene position: 783855-785387 (Clockwise)

Preceding gene: 114798096

Following gene: 114800082

Centisome position: 21.16

GC content: 63.14

Gene sequence:

>1533_bases
TTGCCATTGAAGCTCGCCATTGTCGGCCGGCCAAATGTCGGTAAATCGACGCTTTTCAACCGTCTGGTTGGAAAGAAGAT
TGCGCTTGTGGATGACCAGCCGGGCGTGACCCGCGACCGCAAGATGGCAGACGGGCGCCTCGCGTCCCTGCCTCTGTCGC
TGATTGATACCGCCGGTTTCGACAATGTGAACGATGACAGTCTTGAGGCGCGGATGCGTGCCCAGACTGAAGCGGCCATC
GCCGAGGCCGATCTGGTTCTCTTTCTGGTGGATGCCCGCGTGGGCGTGACCCCGGAAGACGAGACCTTTGCCGGCCTGCT
GCGCAAGGCAAACATTCCCGTGGTTCTGGCGGCCAACAAGGCGGAAGGCCGCGCCGGGGAAGCGGGCGTATTCGATGCAT
TCCGTCTGGGCTTTGGAGAACCTGTCGGCCTGTCGGCTGAGCATGGCGAAGGCATGGCGGAGCTGTATGAATCAATCCGC
AACGCGCTCGGCCCGGAAGCCTATGAGCGCGCGCTGGAAGAAGCCGAACCCGATTATGAGCGCGGCGCCGGGGAAGACAT
CCTCGAAAAGCTCGCCCATATCGACATCGAAGACACGACGCTTTCCGATGATGATCTCGTAGCGGCCATCGAAGCGGCAG
ACATCGACGCCGATGTCGCCGAAGCGCCGGTCCAGTCTGACCGCCCGATCCGCCTGGCCATCGTCGGGCGCCCCAATGCG
GGCAAGTCGACGCTGATCAACCAGCTTCTCCAGTCAGACCGCATGCTGACGGGACCTGAAGCGGGCATCACGCGCGATTC
CATCACCGTGAACTGGGAGTGGGAAGGCCGCCAGATCCGTCTGGTCGATACCGCAGGTCTGCGCCGGAAGAACAAGGTTC
AGGAACGCCTCGAGCGGATGTCGACGGCGGAAACGATCCGGTCCCTGAAATATGCCGACATTGTTGCGCTCGTGATGGAC
GCGCATGAGGCGATGGAGAAGCAGGACCTGCAGATCGCGGACCTCGCGCTGCGCGAAGGCCGGGGCGTCGTGCTCGTCAT
CTCCAAATGGGATACGGTCGAAGATACGGACGGCGCCGCGCGCCATATCCGCGATCTGGCCAACCGGCTGATGCCAAATG
CAGGCGGCGCGCCGGTCGTATTCCTCTCGGGTCTGACGGGTCGCAATATCGAGAAGCTGATGCCGGCGGTCGTGAAGGTC
TACAAGGACTGGACCGCGCGCGCGAAGACCGGCGACCTCAATCGCTGGCTGCGTCACACGGTAGAGCATCACCCGCCGCC
GAGCGTGCAGGGCAAGCGGATCAAGCCGCGCTACATGGCCCAGATGAAAGCCCGCCCGCCGACCTTCGTTCTGATTGCCT
CACGCGGCGATCAGATGCCGGAGGGCTACAAGCGCTATCTGGTCAACGGCATCCGCGAGGCGTTCGACATGCATGGCGTG
CCGATCCGGCTTTTCGTGCGGCAGGGCAAGAACCCGTATGCCGGCAAGGTGGGGGCTGATGGCCCGCCGCGCCACAAGCG
CCGAAATAACTGA

Upstream 100 bases:

>100_bases
AAGCTTTATGTCCTGACGGACGAGGCGCGCCTGATCGCCATCAGATAATTCCGGCCGGGGGCAGTCCTTCCGGCCTTAGC
CGCTGCGGAGGGCTTTTGCC

Downstream 100 bases:

>100_bases
CAACGATCCGCCGTCGGACGGATGATAATCGCTTATTTCGGTTGGAGCGGCGCGGTATCTGATATCATAGATAGGCGTCA
AGACCTCGTGCCCTGAGTTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MPLKLAIVGRPNVGKSTLFNRLVGKKIALVDDQPGVTRDRKMADGRLASLPLSLIDTAGFDNVNDDSLEARMRAQTEAAI
AEADLVLFLVDARVGVTPEDETFAGLLRKANIPVVLAANKAEGRAGEAGVFDAFRLGFGEPVGLSAEHGEGMAELYESIR
NALGPEAYERALEEAEPDYERGAGEDILEKLAHIDIEDTTLSDDDLVAAIEAADIDADVAEAPVQSDRPIRLAIVGRPNA
GKSTLINQLLQSDRMLTGPEAGITRDSITVNWEWEGRQIRLVDTAGLRRKNKVQERLERMSTAETIRSLKYADIVALVMD
AHEAMEKQDLQIADLALREGRGVVLVISKWDTVEDTDGAARHIRDLANRLMPNAGGAPVVFLSGLTGRNIEKLMPAVVKV
YKDWTARAKTGDLNRWLRHTVEHHPPPSVQGKRIKPRYMAQMKARPPTFVLIASRGDQMPEGYKRYLVNGIREAFDMHGV
PIRLFVRQGKNPYAGKVGADGPPRHKRRNN

Sequences:

>Translated_510_residues
MPLKLAIVGRPNVGKSTLFNRLVGKKIALVDDQPGVTRDRKMADGRLASLPLSLIDTAGFDNVNDDSLEARMRAQTEAAI
AEADLVLFLVDARVGVTPEDETFAGLLRKANIPVVLAANKAEGRAGEAGVFDAFRLGFGEPVGLSAEHGEGMAELYESIR
NALGPEAYERALEEAEPDYERGAGEDILEKLAHIDIEDTTLSDDDLVAAIEAADIDADVAEAPVQSDRPIRLAIVGRPNA
GKSTLINQLLQSDRMLTGPEAGITRDSITVNWEWEGRQIRLVDTAGLRRKNKVQERLERMSTAETIRSLKYADIVALVMD
AHEAMEKQDLQIADLALREGRGVVLVISKWDTVEDTDGAARHIRDLANRLMPNAGGAPVVFLSGLTGRNIEKLMPAVVKV
YKDWTARAKTGDLNRWLRHTVEHHPPPSVQGKRIKPRYMAQMKARPPTFVLIASRGDQMPEGYKRYLVNGIREAFDMHGV
PIRLFVRQGKNPYAGKVGADGPPRHKRRNN
>Mature_509_residues
PLKLAIVGRPNVGKSTLFNRLVGKKIALVDDQPGVTRDRKMADGRLASLPLSLIDTAGFDNVNDDSLEARMRAQTEAAIA
EADLVLFLVDARVGVTPEDETFAGLLRKANIPVVLAANKAEGRAGEAGVFDAFRLGFGEPVGLSAEHGEGMAELYESIRN
ALGPEAYERALEEAEPDYERGAGEDILEKLAHIDIEDTTLSDDDLVAAIEAADIDADVAEAPVQSDRPIRLAIVGRPNAG
KSTLINQLLQSDRMLTGPEAGITRDSITVNWEWEGRQIRLVDTAGLRRKNKVQERLERMSTAETIRSLKYADIVALVMDA
HEAMEKQDLQIADLALREGRGVVLVISKWDTVEDTDGAARHIRDLANRLMPNAGGAPVVFLSGLTGRNIEKLMPAVVKVY
KDWTARAKTGDLNRWLRHTVEHHPPPSVQGKRIKPRYMAQMKARPPTFVLIASRGDQMPEGYKRYLVNGIREAFDMHGVP
IRLFVRQGKNPYAGKVGADGPPRHKRRNN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=504, Percent_Identity=36.5079365079365, Blast_Score=308, Evalue=4e-85,
Organism=Escherichia coli, GI1788919, Length=194, Percent_Identity=32.9896907216495, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI2367268, Length=242, Percent_Identity=32.6446280991736, Blast_Score=73, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323665, Length=184, Percent_Identity=29.3478260869565, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_HYPNA (Q0C441)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_759502.1
- ProteinModelPortal:   Q0C441
- SMR:   Q0C441
- STRING:   Q0C441
- GeneID:   4287235
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_0774
- NMPDR:   fig|228405.5.peg.757
- TIGR:   HNE_0774
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q0C441
- ProtClustDB:   PRK00093
- BioCyc:   HNEP81032:HNE_0774-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 56051; Mature: 55919

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKLAIVGRPNVGKSTLFNRLVGKKIALVDDQPGVTRDRKMADGRLASLPLSLIDTAGF
CCEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCCCHHHCCCCHHHCCHHHHHCCCC
DNVNDDSLEARMRAQTEAAIAEADLVLFLVDARVGVTPEDETFAGLLRKANIPVVLAANK
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECC
AEGRAGEAGVFDAFRLGFGEPVGLSAEHGEGMAELYESIRNALGPEAYERALEEAEPDYE
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
RGAGEDILEKLAHIDIEDTTLSDDDLVAAIEAADIDADVAEAPVQSDRPIRLAIVGRPNA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCEEEEEEECCCC
GKSTLINQLLQSDRMLTGPEAGITRDSITVNWEWEGRQIRLVDTAGLRRKNKVQERLERM
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHH
STAETIRSLKYADIVALVMDAHEAMEKQDLQIADLALREGRGVVLVISKWDTVEDTDGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHH
RHIRDLANRLMPNAGGAPVVFLSGLTGRNIEKLMPAVVKVYKDWTARAKTGDLNRWLRHT
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VEHHPPPSVQGKRIKPRYMAQMKARPPTFVLIASRGDQMPEGYKRYLVNGIREAFDMHGV
HHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
PIRLFVRQGKNPYAGKVGADGPPRHKRRNN
CEEEEEECCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLKLAIVGRPNVGKSTLFNRLVGKKIALVDDQPGVTRDRKMADGRLASLPLSLIDTAGF
CEEEEEECCCCCCHHHHHHHHHCCEEEEECCCCCCCCCHHHCCCCHHHCCHHHHHCCCC
DNVNDDSLEARMRAQTEAAIAEADLVLFLVDARVGVTPEDETFAGLLRKANIPVVLAANK
CCCCCHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECC
AEGRAGEAGVFDAFRLGFGEPVGLSAEHGEGMAELYESIRNALGPEAYERALEEAEPDYE
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCHH
RGAGEDILEKLAHIDIEDTTLSDDDLVAAIEAADIDADVAEAPVQSDRPIRLAIVGRPNA
CCCCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCEEEEEEECCCC
GKSTLINQLLQSDRMLTGPEAGITRDSITVNWEWEGRQIRLVDTAGLRRKNKVQERLERM
CHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHH
STAETIRSLKYADIVALVMDAHEAMEKQDLQIADLALREGRGVVLVISKWDTVEDTDGAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEEEECCCCCCCCCHHH
RHIRDLANRLMPNAGGAPVVFLSGLTGRNIEKLMPAVVKVYKDWTARAKTGDLNRWLRHT
HHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
VEHHPPPSVQGKRIKPRYMAQMKARPPTFVLIASRGDQMPEGYKRYLVNGIREAFDMHGV
HHCCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
PIRLFVRQGKNPYAGKVGADGPPRHKRRNN
CEEEEEECCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA