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The map label for this gene is lepB [H]

Identifier: 114798259

GI number: 114798259

Start: 1900020

End: 1900796

Strand: Reverse

Name: lepB [H]

Synonym: HNE_1842

Alternate gene names: 114798259

Gene position: 1900796-1900020 (Counterclockwise)

Preceding gene: 114799081

Following gene: 114800175

Centisome position: 51.3

GC content: 61.0

Gene sequence:

>777_bases
TTGCGCGAATGGGGCGCGACACTTGCGATCGTCGCGCCCGCCTTTCTCCTCTTCACCGGCCTGCTCTACGAGCAGCGGGT
GATTCCCTCCGAAAGCATGGTTCCGACGCTTGAAGTCGGTGACCGGGTTGCGGTTTCCAAATTTGCCTTCGGGTATGGCC
GGTATTCCCTGCCGCTGAGTATCGGGCGTTACCTGCCACTTGGTGGCGGTCGCTTTTTTGCCAGCACGCCCGAACGCGGC
GATGTGGTTGTGTTTGAACACACCCATTCGGAACGGGTCATGATCAAGCGGGTGGTCGGCTTGCCCGGCGATACCGTTCA
GATGATCAATGAGGAGCTGGTGATCAATGGCCAGCCGATTGAGGCAGAGTTCGTACGGACGGTGCGGTATGTGCCCGACC
GGACCGATGTGGTGGATACCGCGCATGAATGGCGCGAAACCATCGGCGACAAGACCTGGCTGACGCATCGCGGCCTTCGC
GGCCACACGGTGGATGACACGGCGCTCTTTGTCGTGCCCGAGGGGCATATGTTCCTGGTGGGGGACAATCGAAATAATTC
CTATGACAGCCGTGAGCTGTCGGGCCATTGCCCCCCTGTGAACGGTGTTGTGGATCGCGCGGGCTGCCCGCTGCGCGTGC
CGGCCGATGACGCCTCGATCGGGTTTGTGCCCCTGGACCATCTGATCGGGCGTGCTGATACGGTTCTGATGACGTTCCAT
CGCTGCAAGCTGCAGGATGATGAGCCCTGCCAGAAACGCGTATGGCGCGGACTTTGA

Upstream 100 bases:

>100_bases
TGCCGGATTGCCTGTGATTGGGGTTTGAATGACTGAGGAAAACAGCGTGCCGGACGAGGCACCGCCGCAGGCGGGTCTTT
GGGCAAAGGTCAAGCAGGAG

Downstream 100 bases:

>100_bases
GGCGCCAATCCATATCTTGCCCGCTCGGGCCAACACCGCTAGTCGGGGTCTGACCGGGGCGCTGGGCCCTGTGGCAACAC
GGAAATTTGGCGATGCCCAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MREWGATLAIVAPAFLLFTGLLYEQRVIPSESMVPTLEVGDRVAVSKFAFGYGRYSLPLSIGRYLPLGGGRFFASTPERG
DVVVFEHTHSERVMIKRVVGLPGDTVQMINEELVINGQPIEAEFVRTVRYVPDRTDVVDTAHEWRETIGDKTWLTHRGLR
GHTVDDTALFVVPEGHMFLVGDNRNNSYDSRELSGHCPPVNGVVDRAGCPLRVPADDASIGFVPLDHLIGRADTVLMTFH
RCKLQDDEPCQKRVWRGL

Sequences:

>Translated_258_residues
MREWGATLAIVAPAFLLFTGLLYEQRVIPSESMVPTLEVGDRVAVSKFAFGYGRYSLPLSIGRYLPLGGGRFFASTPERG
DVVVFEHTHSERVMIKRVVGLPGDTVQMINEELVINGQPIEAEFVRTVRYVPDRTDVVDTAHEWRETIGDKTWLTHRGLR
GHTVDDTALFVVPEGHMFLVGDNRNNSYDSRELSGHCPPVNGVVDRAGCPLRVPADDASIGFVPLDHLIGRADTVLMTFH
RCKLQDDEPCQKRVWRGL
>Mature_258_residues
MREWGATLAIVAPAFLLFTGLLYEQRVIPSESMVPTLEVGDRVAVSKFAFGYGRYSLPLSIGRYLPLGGGRFFASTPERG
DVVVFEHTHSERVMIKRVVGLPGDTVQMINEELVINGQPIEAEFVRTVRYVPDRTDVVDTAHEWRETIGDKTWLTHRGLR
GHTVDDTALFVVPEGHMFLVGDNRNNSYDSRELSGHCPPVNGVVDRAGCPLRVPADDASIGFVPLDHLIGRADTVLMTFH
RCKLQDDEPCQKRVWRGL

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=286, Percent_Identity=30.0699300699301, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 28840; Mature: 28840

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREWGATLAIVAPAFLLFTGLLYEQRVIPSESMVPTLEVGDRVAVSKFAFGYGRYSLPLS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHCCCCEECCEE
IGRYLPLGGGRFFASTPERGDVVVFEHTHSERVMIKRVVGLPGDTVQMINEELVINGQPI
CCCEEECCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHCCCEEEECCCCC
EAEFVRTVRYVPDRTDVVDTAHEWRETIGDKTWLTHRGLRGHTVDDTALFVVPEGHMFLV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCEEEE
GDNRNNSYDSRELSGHCPPVNGVVDRAGCPLRVPADDASIGFVPLDHLIGRADTVLMTFH
ECCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECCCCCCCCCEEEHHHHHCCHHHEEEEEE
RCKLQDDEPCQKRVWRGL
HHCCCCCCHHHHHHHCCC
>Mature Secondary Structure
MREWGATLAIVAPAFLLFTGLLYEQRVIPSESMVPTLEVGDRVAVSKFAFGYGRYSLPLS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHCCCCEECCEE
IGRYLPLGGGRFFASTPERGDVVVFEHTHSERVMIKRVVGLPGDTVQMINEELVINGQPI
CCCEEECCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHHHCCCEEEECCCCC
EAEFVRTVRYVPDRTDVVDTAHEWRETIGDKTWLTHRGLRGHTVDDTALFVVPEGHMFLV
HHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEEECCCEEEE
GDNRNNSYDSRELSGHCPPVNGVVDRAGCPLRVPADDASIGFVPLDHLIGRADTVLMTFH
ECCCCCCCCCCCCCCCCCCCCCHHHCCCCCEECCCCCCCCCEEEHHHHHCCHHHEEEEEE
RCKLQDDEPCQKRVWRGL
HHCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA