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The map label for this gene is frc [H]

Identifier: 114798254

GI number: 114798254

Start: 143838

End: 145013

Strand: Reverse

Name: frc [H]

Synonym: HNE_0162

Alternate gene names: 114798254

Gene position: 145013-143838 (Counterclockwise)

Preceding gene: 114797399

Following gene: 114799614

Centisome position: 3.91

GC content: 60.54

Gene sequence:

>1176_bases
ATGACCGATAAGTCCCGTCCCGGCCCACTCTCGGGTATGCGCATCGTCGATATGAGTTCTGTCGTTCTCGGGCCGTTCGC
AACGCTCATTCTCGCCGATCTCGGGGCAGAGGTCATCAAGATCGAACCGCCCAAAAAGCGCGATACCATGCGCTATGCTG
GCGCCTCCCCAACTGGCGATCTCGGCCCCATCTATATGGCGCTCAACCGCAACAAGCGGGCATTGACGCTCGACGCCAAG
ACACCGGAGGGGAAAGCCGCCCTCACCGAGCTTCTGAAAACGGCAGACTGCTTCTTCCACAATGTGCGCCTCGCCGGCAT
GGAACGGCTCGGATTTGGCTATGAACAGGTCAAGGCGCTGAAGGAGGACATCGTCTACGTCCATTGCGCGGGCTTTGGCA
AAGGCGGCCCCTATGAACACCGCCAGGCCTATGATGACCTCATTCAGGGCGCATCGGGCTTTGCAGATCTCAACGCCCTG
CGCTCGGGCGGCCGCCCCGAATACGCGCCCTCTCTCGTCGCAGACAAGACGGCCGGGCTTTTCGCAACCTATGCAACGCT
CGCCGCGCTCCTTCACCGCGCCCGCTCCGGCAAGGGTCAGTTCGTGCAGGTGCCGATGCTGGAGAGTTTCACCTTCTTCA
ACATGGTCGAAAATCTCTATGGCGAGACCTTCCTGCCCGGCAATGGCAAGCTCGCCTATACGCGCTCCATCAATCCCAAT
CGCCGCCCCTACCCCACGAAAGACGGCTTCATCGGGCTTGTTCCGTATTCGGACGAGCAGTGGGAAAAGTTCTTCCAGAT
CGGCGGCATGCCCGACATCTTCAAGGACCCGCGCTTCTCCACTTATCAGGCGCGCACCGAAAATGTCGGCGACCTGTACG
CCCTCATCGAAAAGGTAAGCGCGACGAAGACGACCGCTGAATGGCTGGAACTGATGGACAAGGCCGACATTCCGGCCATG
CGCTACAACACGATGGCCGAAGTGCTGACCGACCCTCACCTTGTAGCTACCGGCTTTTTCACCGAAGCGGAACATCCCGA
GGCGGGAAAGTATAGGACCATGCGCCATCCGGTCCATTTTTCCGAAACGCCCGCCAGCTTGCGCCTGCCGCCCCCGCGGC
CAGGCGCTGATACGGAAAGTATCCTGGAGAGCCTCGGCCTTGGCGCAGAGGGGTAA

Upstream 100 bases:

>100_bases
ATCGAAGAAGCCCGCGTCGCCCTCGCGCTATAACGCAAGGGAATGCCTTGATCTTCGCAGCGCGCTACAGGCACTTACCC
GAAAAATATGGAGGCCCTTA

Downstream 100 bases:

>100_bases
TCAGCCCCCGGAAAGGCGGGCCATCTCGTCTTCAGAGATTTCCGAATTGTCGTAGACACTCTGAACATCGTCGAGCTCAT
CGAGCACATCGAGCATCTTC

Product: L-carnitine dehydratase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 391; Mature: 390

Protein sequence:

>391_residues
MTDKSRPGPLSGMRIVDMSSVVLGPFATLILADLGAEVIKIEPPKKRDTMRYAGASPTGDLGPIYMALNRNKRALTLDAK
TPEGKAALTELLKTADCFFHNVRLAGMERLGFGYEQVKALKEDIVYVHCAGFGKGGPYEHRQAYDDLIQGASGFADLNAL
RSGGRPEYAPSLVADKTAGLFATYATLAALLHRARSGKGQFVQVPMLESFTFFNMVENLYGETFLPGNGKLAYTRSINPN
RRPYPTKDGFIGLVPYSDEQWEKFFQIGGMPDIFKDPRFSTYQARTENVGDLYALIEKVSATKTTAEWLELMDKADIPAM
RYNTMAEVLTDPHLVATGFFTEAEHPEAGKYRTMRHPVHFSETPASLRLPPPRPGADTESILESLGLGAEG

Sequences:

>Translated_391_residues
MTDKSRPGPLSGMRIVDMSSVVLGPFATLILADLGAEVIKIEPPKKRDTMRYAGASPTGDLGPIYMALNRNKRALTLDAK
TPEGKAALTELLKTADCFFHNVRLAGMERLGFGYEQVKALKEDIVYVHCAGFGKGGPYEHRQAYDDLIQGASGFADLNAL
RSGGRPEYAPSLVADKTAGLFATYATLAALLHRARSGKGQFVQVPMLESFTFFNMVENLYGETFLPGNGKLAYTRSINPN
RRPYPTKDGFIGLVPYSDEQWEKFFQIGGMPDIFKDPRFSTYQARTENVGDLYALIEKVSATKTTAEWLELMDKADIPAM
RYNTMAEVLTDPHLVATGFFTEAEHPEAGKYRTMRHPVHFSETPASLRLPPPRPGADTESILESLGLGAEG
>Mature_390_residues
TDKSRPGPLSGMRIVDMSSVVLGPFATLILADLGAEVIKIEPPKKRDTMRYAGASPTGDLGPIYMALNRNKRALTLDAKT
PEGKAALTELLKTADCFFHNVRLAGMERLGFGYEQVKALKEDIVYVHCAGFGKGGPYEHRQAYDDLIQGASGFADLNALR
SGGRPEYAPSLVADKTAGLFATYATLAALLHRARSGKGQFVQVPMLESFTFFNMVENLYGETFLPGNGKLAYTRSINPNR
RPYPTKDGFIGLVPYSDEQWEKFFQIGGMPDIFKDPRFSTYQARTENVGDLYALIEKVSATKTTAEWLELMDKADIPAMR
YNTMAEVLTDPHLVATGFFTEAEHPEAGKYRTMRHPVHFSETPASLRLPPPRPGADTESILESLGLGAEG

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=389, Percent_Identity=29.305912596401, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI300863124, Length=415, Percent_Identity=27.710843373494, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI300863126, Length=384, Percent_Identity=26.8229166666667, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI13376042, Length=415, Percent_Identity=26.0240963855422, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI266456254, Length=400, Percent_Identity=28, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI42794625, Length=400, Percent_Identity=28, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI266458393, Length=208, Percent_Identity=31.7307692307692, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI266458397, Length=208, Percent_Identity=31.7307692307692, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI42822893, Length=137, Percent_Identity=32.1167883211679, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI266458395, Length=137, Percent_Identity=32.1167883211679, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788717, Length=405, Percent_Identity=28.8888888888889, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI87082093, Length=361, Percent_Identity=29.0858725761773, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786222, Length=396, Percent_Identity=28.7878787878788, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI115535051, Length=341, Percent_Identity=24.0469208211144, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32564160, Length=278, Percent_Identity=25.1798561151079, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24648431, Length=394, Percent_Identity=31.9796954314721, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24585488, Length=398, Percent_Identity=26.1306532663317, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 42988; Mature: 42856

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKSRPGPLSGMRIVDMSSVVLGPFATLILADLGAEVIKIEPPKKRDTMRYAGASPTGD
CCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCCC
LGPIYMALNRNKRALTLDAKTPEGKAALTELLKTADCFFHNVRLAGMERLGFGYEQVKAL
CCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KEDIVYVHCAGFGKGGPYEHRQAYDDLIQGASGFADLNALRSGGRPEYAPSLVADKTAGL
HHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
FATYATLAALLHRARSGKGQFVQVPMLESFTFFNMVENLYGETFLPGNGKLAYTRSINPN
HHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCC
RRPYPTKDGFIGLVPYSDEQWEKFFQIGGMPDIFKDPRFSTYQARTENVGDLYALIEKVS
CCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCHHCCCCCCCHHHCCCCHHHHHHHHHHHH
ATKTTAEWLELMDKADIPAMRYNTMAEVLTDPHLVATGFFTEAEHPEAGKYRTMRHPVHF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHCCCCCC
SETPASLRLPPPRPGADTESILESLGLGAEG
CCCCCCEECCCCCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
TDKSRPGPLSGMRIVDMSSVVLGPFATLILADLGAEVIKIEPPKKRDTMRYAGASPTGD
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCEECCCCCCCC
LGPIYMALNRNKRALTLDAKTPEGKAALTELLKTADCFFHNVRLAGMERLGFGYEQVKAL
CCCEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KEDIVYVHCAGFGKGGPYEHRQAYDDLIQGASGFADLNALRSGGRPEYAPSLVADKTAGL
HHCEEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHH
FATYATLAALLHRARSGKGQFVQVPMLESFTFFNMVENLYGETFLPGNGKLAYTRSINPN
HHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCC
RRPYPTKDGFIGLVPYSDEQWEKFFQIGGMPDIFKDPRFSTYQARTENVGDLYALIEKVS
CCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCHHCCCCCCCHHHCCCCHHHHHHHHHHHH
ATKTTAEWLELMDKADIPAMRYNTMAEVLTDPHLVATGFFTEAEHPEAGKYRTMRHPVHF
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHCCCCCC
SETPASLRLPPPRPGADTESILESLGLGAEG
CCCCCCEECCCCCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA