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The map label for this gene is yabD [H]

Identifier: 114798238

GI number: 114798238

Start: 1857862

End: 1858638

Strand: Reverse

Name: yabD [H]

Synonym: HNE_1811

Alternate gene names: 114798238

Gene position: 1858638-1857862 (Counterclockwise)

Preceding gene: 114798506

Following gene: 114798446

Centisome position: 50.17

GC content: 57.01

Gene sequence:

>777_bases
ATGTTTGATACGCATGTAAACCTGCATGGCGAAGCTTTTGCAGACGATCTGCAGGACGTTCTGGGCCGGGCGCGCGAAGC
GGGCGTGCGGCGGTTCCTGGCTATATGCGATCGGTTCGACAATTTCCCGGCCGTGCACGCGATTGCCAAAGCCGAGAACG
ACATGTGGTGCTCCGTAGGCACCCATCCTCACCATGCGAAGGACTTCACCAGCCTGACGCCTGAAATGCTGATCGATGCC
GCTCAAGACGACAAGGTTGTTGCCATAGGCGAAACCGGGCTGGATTTTCATTACGGATACAGTCCGGAGAAGGAGCAGGT
CGCAAGCCTGTTGACGCATATTGTTGCGGCCCGGAAAACAGACCTTCCGCTAATCCTGCACACGCGGGAGGCGGATGATC
AGATGGCCGATATTCTTGAGACGGAGATAGCCAAAGGCGCATTCCGGCCGTTATTGCATTGCTACACTGGCGGTGAAGGC
CTGGCGAAGCGCGCGCTCGCGTGTGGCGCATATTTTTCCGTATCGGGAATATTGTCATTCAAGAGCGCAAAGGATGTCCG
TTCGGTTATGAGTGAGGTTCCCATGGAGCGGATCATTCTGGAGACGGATTGCCCTTATCTGGCACCTGTGCCGATGCGGG
GACGGCGCAACGAGCCAGCGTATCTGGCCCATGTCGCAGAGGCGCTCGCAGCGCTTAAGGGTATGCCTGTGGATGAGGTC
AAAGCGATTACAGAGGCGAATGCTCTGACGCTGTTTTCCAAGGTGAGCGTGGCGTGA

Upstream 100 bases:

>100_bases
TCTGGCGATGCGGAGACCTTGAACATGGACGCCGCCCAAGTGGCCTCCAAGATAATCGCGGCGATGTATGACGCCGCCCC
AGCCAAGTGAATGATCTTTG

Downstream 100 bases:

>100_bases
GTGATGCACGGATCATCCTGCTGGGCACTGGATCTTCAGGCGGCGTCCCGCGTGTCGGGGGCGACTGGGGCGCGTGTGAT
CCGGCTGAACCGAAAAATCG

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MFDTHVNLHGEAFADDLQDVLGRAREAGVRRFLAICDRFDNFPAVHAIAKAENDMWCSVGTHPHHAKDFTSLTPEMLIDA
AQDDKVVAIGETGLDFHYGYSPEKEQVASLLTHIVAARKTDLPLILHTREADDQMADILETEIAKGAFRPLLHCYTGGEG
LAKRALACGAYFSVSGILSFKSAKDVRSVMSEVPMERIILETDCPYLAPVPMRGRRNEPAYLAHVAEALAALKGMPVDEV
KAITEANALTLFSKVSVA

Sequences:

>Translated_258_residues
MFDTHVNLHGEAFADDLQDVLGRAREAGVRRFLAICDRFDNFPAVHAIAKAENDMWCSVGTHPHHAKDFTSLTPEMLIDA
AQDDKVVAIGETGLDFHYGYSPEKEQVASLLTHIVAARKTDLPLILHTREADDQMADILETEIAKGAFRPLLHCYTGGEG
LAKRALACGAYFSVSGILSFKSAKDVRSVMSEVPMERIILETDCPYLAPVPMRGRRNEPAYLAHVAEALAALKGMPVDEV
KAITEANALTLFSKVSVA
>Mature_258_residues
MFDTHVNLHGEAFADDLQDVLGRAREAGVRRFLAICDRFDNFPAVHAIAKAENDMWCSVGTHPHHAKDFTSLTPEMLIDA
AQDDKVVAIGETGLDFHYGYSPEKEQVASLLTHIVAARKTDLPLILHTREADDQMADILETEIAKGAFRPLLHCYTGGEG
LAKRALACGAYFSVSGILSFKSAKDVRSVMSEVPMERIILETDCPYLAPVPMRGRRNEPAYLAHVAEALAALKGMPVDEV
KAITEANALTLFSKVSVA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=31.6363636363636, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=30.5970149253731, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=30.5970149253731, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI226061614, Length=260, Percent_Identity=29.6153846153846, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI225903424, Length=208, Percent_Identity=30.2884615384615, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI14042943, Length=267, Percent_Identity=25.0936329588015, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI226061595, Length=229, Percent_Identity=29.6943231441048, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI225903439, Length=242, Percent_Identity=23.5537190082645, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787342, Length=256, Percent_Identity=35.546875, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI48994985, Length=259, Percent_Identity=32.8185328185328, Blast_Score=148, Evalue=4e-37,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=29.9610894941634, Blast_Score=115, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17559024, Length=294, Percent_Identity=31.2925170068027, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=265, Percent_Identity=27.1698113207547, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=30.3738317757009, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17543026, Length=214, Percent_Identity=26.6355140186916, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI221330018, Length=271, Percent_Identity=26.9372693726937, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24586117, Length=271, Percent_Identity=26.9372693726937, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648690, Length=285, Percent_Identity=27.0175438596491, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28205; Mature: 28205

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDTHVNLHGEAFADDLQDVLGRAREAGVRRFLAICDRFDNFPAVHAIAKAENDMWCSVG
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECC
THPHHAKDFTSLTPEMLIDAAQDDKVVAIGETGLDFHYGYSPEKEQVASLLTHIVAARKT
CCCCCHHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
DLPLILHTREADDQMADILETEIAKGAFRPLLHCYTGGEGLAKRALACGAYFSVSGILSF
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KSAKDVRSVMSEVPMERIILETDCPYLAPVPMRGRRNEPAYLAHVAEALAALKGMPVDEV
HHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
KAITEANALTLFSKVSVA
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFDTHVNLHGEAFADDLQDVLGRAREAGVRRFLAICDRFDNFPAVHAIAKAENDMWCSVG
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEECC
THPHHAKDFTSLTPEMLIDAAQDDKVVAIGETGLDFHYGYSPEKEQVASLLTHIVAARKT
CCCCCHHHHHHCCHHHHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
DLPLILHTREADDQMADILETEIAKGAFRPLLHCYTGGEGLAKRALACGAYFSVSGILSF
CCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KSAKDVRSVMSEVPMERIILETDCPYLAPVPMRGRRNEPAYLAHVAEALAALKGMPVDEV
HHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
KAITEANALTLFSKVSVA
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]