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The map label for this gene is lipB [H]

Identifier: 114798446

GI number: 114798446

Start: 1857062

End: 1857865

Strand: Reverse

Name: lipB [H]

Synonym: HNE_1810

Alternate gene names: 114798446

Gene position: 1857865-1857062 (Counterclockwise)

Preceding gene: 114798238

Following gene: 114797193

Centisome position: 50.14

GC content: 57.84

Gene sequence:

>804_bases
GTGAGTGATGCACGGATCATCCTGCTGGGCACTGGATCTTCAGGCGGCGTCCCGCGTGTCGGGGGCGACTGGGGCGCGTG
TGATCCGGCTGAACCGAAAAATCGCCGGAGGAGATGCTGCGCGCTTGTTCAGAGGTTCGGCGCGGGCGACGCGCTTACCA
ACATCCTGATTGATACGTCACCGGACCTGAGGGAACAGCTTCTCGAAGCGGAGGTGATGCATCTGGACGCCGTGATTTAC
ACGCATGATCATGCAGACCAGTCGCACGGTATTGATGACGTTCGCGCGCTTGCCATTCGGCAGAGGCGCGCGATCCCTGT
GTATTTTGATCCGTATGCCCGCAACAGTCTGATGACGCGGTTTGAGTATTGTTTCATTGGGGGGAAGGGCTATCCGGCAA
TTTTGTCGCCGCACACAACCGTCAATGAAGGGCAGGCATTCAGCGTCACCGGAGCAGGCGGCACTGTGGAATTCCTTCCT
GTCTCGATGATCCACGGCCCCATTCCATGCACAGGTTACCGGATTGGAAATGTCGCCTATTGCAATGACGTTAATGAGTT
GCCGGCTACCGCGCTCCGGCAACTTGGTGGGTTGGATGTGCTGATTATTGACGCGTTGCGTCACACGCCGCATCCGTCCC
ACGCGCACCTTGAGCTGGCGCTTGAATGGATCAAGGAACTCCGGCCCAAAAGAGCAGTTCTGACGAACCTGCATGTCGAC
ATGGATTACCAGACGCTGCGCCGGACGCTGCCGGCGAATGTCGAGCCTGGGTTTGATGGCATGACGATCAGCATTGAAAG
CTGA

Upstream 100 bases:

>100_bases
TCGCAGAGGCGCTCGCAGCGCTTAAGGGTATGCCTGTGGATGAGGTCAAAGCGATTACAGAGGCGAATGCTCTGACGCTG
TTTTCCAAGGTGAGCGTGGC

Downstream 100 bases:

>100_bases
TGGGCACCAGGGCGGATGGAGCCGGGCTTCCGCCGCCATTGCAAGAGCTCCAGAATCGCATCTGATTACAAGGCGCTATA
AAGGCAGTGGCCGCTATAAC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MSDARIILLGTGSSGGVPRVGGDWGACDPAEPKNRRRRCCALVQRFGAGDALTNILIDTSPDLREQLLEAEVMHLDAVIY
THDHADQSHGIDDVRALAIRQRRAIPVYFDPYARNSLMTRFEYCFIGGKGYPAILSPHTTVNEGQAFSVTGAGGTVEFLP
VSMIHGPIPCTGYRIGNVAYCNDVNELPATALRQLGGLDVLIIDALRHTPHPSHAHLELALEWIKELRPKRAVLTNLHVD
MDYQTLRRTLPANVEPGFDGMTISIES

Sequences:

>Translated_267_residues
MSDARIILLGTGSSGGVPRVGGDWGACDPAEPKNRRRRCCALVQRFGAGDALTNILIDTSPDLREQLLEAEVMHLDAVIY
THDHADQSHGIDDVRALAIRQRRAIPVYFDPYARNSLMTRFEYCFIGGKGYPAILSPHTTVNEGQAFSVTGAGGTVEFLP
VSMIHGPIPCTGYRIGNVAYCNDVNELPATALRQLGGLDVLIIDALRHTPHPSHAHLELALEWIKELRPKRAVLTNLHVD
MDYQTLRRTLPANVEPGFDGMTISIES
>Mature_266_residues
SDARIILLGTGSSGGVPRVGGDWGACDPAEPKNRRRRCCALVQRFGAGDALTNILIDTSPDLREQLLEAEVMHLDAVIYT
HDHADQSHGIDDVRALAIRQRRAIPVYFDPYARNSLMTRFEYCFIGGKGYPAILSPHTTVNEGQAFSVTGAGGTVEFLPV
SMIHGPIPCTGYRIGNVAYCNDVNELPATALRQLGGLDVLIIDALRHTPHPSHAHLELALEWIKELRPKRAVLTNLHVDM
DYQTLRRTLPANVEPGFDGMTISIES

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG1235

COG function: function code R; Metal-dependent hydrolases of the beta-lactamase superfamily I

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lipB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605 [H]

Pfam domain/function: PF03099 BPL_LipA_LipB; PF00753 Lactamase_B [H]

EC number: =2.3.1.181 [H]

Molecular weight: Translated: 29274; Mature: 29143

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDARIILLGTGSSGGVPRVGGDWGACDPAEPKNRRRRCCALVQRFGAGDALTNILIDTS
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEECCC
PDLREQLLEAEVMHLDAVIYTHDHADQSHGIDDVRALAIRQRRAIPVYFDPYARNSLMTR
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHE
FEYCFIGGKGYPAILSPHTTVNEGQAFSVTGAGGTVEFLPVSMIHGPIPCTGYRIGNVAY
EEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCEEEEEEEEHHCCCCCCCCEEECCEEE
CNDVNELPATALRQLGGLDVLIIDALRHTPHPSHAHLELALEWIKELRPKRAVLTNLHVD
ECCCCCCHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHEEEEEC
MDYQTLRRTLPANVEPGFDGMTISIES
CCHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
SDARIILLGTGSSGGVPRVGGDWGACDPAEPKNRRRRCCALVQRFGAGDALTNILIDTS
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHEEECCC
PDLREQLLEAEVMHLDAVIYTHDHADQSHGIDDVRALAIRQRRAIPVYFDPYARNSLMTR
HHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCEEECCHHHHHHHHE
FEYCFIGGKGYPAILSPHTTVNEGQAFSVTGAGGTVEFLPVSMIHGPIPCTGYRIGNVAY
EEEEEECCCCCCEEECCCCCCCCCCEEEEECCCCEEEEEEEEHHCCCCCCCCEEECCEEE
CNDVNELPATALRQLGGLDVLIIDALRHTPHPSHAHLELALEWIKELRPKRAVLTNLHVD
ECCCCCCHHHHHHHHCCCEEEEEEHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHEEEEEC
MDYQTLRRTLPANVEPGFDGMTISIES
CCHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]