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The map label for this gene is ggt1 [H]

Identifier: 114798236

GI number: 114798236

Start: 2952673

End: 2954583

Strand: Direct

Name: ggt1 [H]

Synonym: HNE_2791

Alternate gene names: 114798236

Gene position: 2952673-2954583 (Clockwise)

Preceding gene: 114799433

Following gene: 114797491

Centisome position: 79.69

GC content: 65.46

Gene sequence:

>1911_bases
ATGAAATACGCTTTGCTGACCGGCGCCGCCTGCGCGCTCGCCCTTGCCGCCTGCGCCCAGACGCCCGAGCCTGCGCCCCA
GGCGCTGGAACCCGCGCCTGTCACCGCCGCGCCGGAAACCACCCCGGCTGCGCGCGAGAATGCAGCCTTCCCGATGACCG
GCCAGCGCCCTGAAAGCGGCCGCCCCATCGCCACCCGCTCGGCCGTCGTCGCCCCCAACGGCGCCGCCGCCACAGCCCAC
CCCCTCGCCACGCAAACTGCTCTGGATGTGCTCAAGGCCGGCGGCACGGCCGTTGACGCCGCCATCGCCGCCAACGCCAT
GCTCGGCCTTGTCGAGCCCACCGGCAACGGCATCGGCGGCGATCTCTATGCCATCGTCTGGGACCCTGAAACAGAGCAGC
TCTACGGCTATAACGGCTCGGGCCGCTCGGCGATGGATGCCACGCTTGAAGATGCCCAGGCCAAGGCCGATCAGTTCAAG
GACGGCAAATCCCTCCCTTCCTACGGCGCCATCACCGTCACCGTGCCGGGCACGGTCGATGGCTGGTTCGCCCTGCATGA
AAAATTCGGCCAGCGTCCGATGGCGGACAATCTCGCCCCGGCCGTAAAATATGCCCGCGAGGGCGCGCCGATCCCGGAGA
TGATCGCCTGGTACTGGTCGCGCGGCCCGCTGCGCTTTGAGCCCGCCTTCGAGCGCGGCGAGCTGGAAGAATTCGCCAAC
GCCAAGAAAACCTATTTTGACCCCACCCCTGTCGCGGGCTCCCTCTTTAAAAATCCCGACCTTGCCAACACGCTGGAGAC
GATCGGAAAAAAGGGCCGCGACGAATTCTATAAAGGCGTCATGGCCAAAGACATGGCGGCCTATTTCAGCCGCATCGGCG
GCAAGCTCGATTATGATGATTTCAACGCCCATACCGGCGACTGGGTTGAGCCGATCTGCGTCGAATACCGCAGCGAAGTG
AAAGTCTGCGAGCTTGGCCCCAACACGCAAGGCGTCGCCGCCCTCCAGATGCTGGAAATGCTTGAGCGCTTTGATCTCAA
ATCCATGGGCTTCGGTTCGCCCGATGCCGTCACCGCCATGGTCGAGGCCAAGCGCCTCGCCTTCGCTGACCGCGCGCTCG
GCTATGCAGACCCCGCTTTCTCCGGCATCGACCCGTCGATCTTCGTTGCCCCCGGCTATAACGCCAAACGCGCCGAAGCC
ATCGACGTCACCCGCGCCATGCCGGAAGTCGCTCCGGGCACGGAGATCACAGACGCGGCCCTGCGCGACGGCGACACCAC
CTACCTCACCGTCACCGACAAGGACGGCATGATGGTGTCCCTCATCCAGTCCAACTATCGCGGCATGGGCTCGGGCCTCG
TTGCCGATGGCATGGGCTTCATGTTCCAGGACCGGGGCGAATTGTTCAGTCTTGATGCGAACCACCCCAACGTCTTCGCC
CCCGGCAAGCGCCCCTTCCACACGATCATTCCGGCCTTCGCCTTCCGCAAGGATCTCCCCGGCTGCCAGACCGCCGCCAC
CGCGCCGGATCTCGCCTGCCCGTATGAGCCCTGGCTCAGCTTCGGCCTCATGGGCGGCGCCACCCAGCCCCAGGGCCATG
TCCAGATCATCACCAACCTGATCGACTTTGACATGGGCCTCCAGGAAGCGGGCGACGCGGCCCGCTGGGAACATGATGGC
GGCTGCGAGCCCACCAATGCCCTCGGCGACGACTGCGATACCGGCACCGGCACCGTCATGCTCGAACGCGGCCTGGCGGG
CATTGCCGATGAACTGGAATCCCGCGGCTACGACGTCGCCTGCTGCGAAGCCAATTATGGCGGCTACCAGGCCATCATGC
GCGACTTCCGCTCCGGCGCCTGGATCGCCGCCACCGAAATGCGCAAAGACGGCAACGCGGATGGGTACTAA

Upstream 100 bases:

>100_bases
AGGCTGAGGCCCGCTATGCGCGCCGGGGCGAGGAAATCGCCGGGCGCCTGGCCACACACTATTTTCCAAAAGATACCCGC
CGCGGCGGAGGAGGATTCGA

Downstream 100 bases:

>100_bases
ACCTGCCGCGGCCCCCGAAGCCCCTCGCGACTGCCCCCTCTGCCCGCGCCTCGTGGCATATCGCGAAGCCGTGCGCGCCA
AAGAGCCCAGCTGGTTCAAC

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MKYALLTGAACALALAACAQTPEPAPQALEPAPVTAAPETTPAARENAAFPMTGQRPESGRPIATRSAVVAPNGAAATAH
PLATQTALDVLKAGGTAVDAAIAANAMLGLVEPTGNGIGGDLYAIVWDPETEQLYGYNGSGRSAMDATLEDAQAKADQFK
DGKSLPSYGAITVTVPGTVDGWFALHEKFGQRPMADNLAPAVKYAREGAPIPEMIAWYWSRGPLRFEPAFERGELEEFAN
AKKTYFDPTPVAGSLFKNPDLANTLETIGKKGRDEFYKGVMAKDMAAYFSRIGGKLDYDDFNAHTGDWVEPICVEYRSEV
KVCELGPNTQGVAALQMLEMLERFDLKSMGFGSPDAVTAMVEAKRLAFADRALGYADPAFSGIDPSIFVAPGYNAKRAEA
IDVTRAMPEVAPGTEITDAALRDGDTTYLTVTDKDGMMVSLIQSNYRGMGSGLVADGMGFMFQDRGELFSLDANHPNVFA
PGKRPFHTIIPAFAFRKDLPGCQTAATAPDLACPYEPWLSFGLMGGATQPQGHVQIITNLIDFDMGLQEAGDAARWEHDG
GCEPTNALGDDCDTGTGTVMLERGLAGIADELESRGYDVACCEANYGGYQAIMRDFRSGAWIAATEMRKDGNADGY

Sequences:

>Translated_636_residues
MKYALLTGAACALALAACAQTPEPAPQALEPAPVTAAPETTPAARENAAFPMTGQRPESGRPIATRSAVVAPNGAAATAH
PLATQTALDVLKAGGTAVDAAIAANAMLGLVEPTGNGIGGDLYAIVWDPETEQLYGYNGSGRSAMDATLEDAQAKADQFK
DGKSLPSYGAITVTVPGTVDGWFALHEKFGQRPMADNLAPAVKYAREGAPIPEMIAWYWSRGPLRFEPAFERGELEEFAN
AKKTYFDPTPVAGSLFKNPDLANTLETIGKKGRDEFYKGVMAKDMAAYFSRIGGKLDYDDFNAHTGDWVEPICVEYRSEV
KVCELGPNTQGVAALQMLEMLERFDLKSMGFGSPDAVTAMVEAKRLAFADRALGYADPAFSGIDPSIFVAPGYNAKRAEA
IDVTRAMPEVAPGTEITDAALRDGDTTYLTVTDKDGMMVSLIQSNYRGMGSGLVADGMGFMFQDRGELFSLDANHPNVFA
PGKRPFHTIIPAFAFRKDLPGCQTAATAPDLACPYEPWLSFGLMGGATQPQGHVQIITNLIDFDMGLQEAGDAARWEHDG
GCEPTNALGDDCDTGTGTVMLERGLAGIADELESRGYDVACCEANYGGYQAIMRDFRSGAWIAATEMRKDGNADGY
>Mature_636_residues
MKYALLTGAACALALAACAQTPEPAPQALEPAPVTAAPETTPAARENAAFPMTGQRPESGRPIATRSAVVAPNGAAATAH
PLATQTALDVLKAGGTAVDAAIAANAMLGLVEPTGNGIGGDLYAIVWDPETEQLYGYNGSGRSAMDATLEDAQAKADQFK
DGKSLPSYGAITVTVPGTVDGWFALHEKFGQRPMADNLAPAVKYAREGAPIPEMIAWYWSRGPLRFEPAFERGELEEFAN
AKKTYFDPTPVAGSLFKNPDLANTLETIGKKGRDEFYKGVMAKDMAAYFSRIGGKLDYDDFNAHTGDWVEPICVEYRSEV
KVCELGPNTQGVAALQMLEMLERFDLKSMGFGSPDAVTAMVEAKRLAFADRALGYADPAFSGIDPSIFVAPGYNAKRAEA
IDVTRAMPEVAPGTEITDAALRDGDTTYLTVTDKDGMMVSLIQSNYRGMGSGLVADGMGFMFQDRGELFSLDANHPNVFA
PGKRPFHTIIPAFAFRKDLPGCQTAATAPDLACPYEPWLSFGLMGGATQPQGHVQIITNLIDFDMGLQEAGDAARWEHDG
GCEPTNALGDDCDTGTGTVMLERGLAGIADELESRGYDVACCEANYGGYQAIMRDFRSGAWIAATEMRKDGNADGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=581, Percent_Identity=24.4406196213425, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI73915090, Length=581, Percent_Identity=24.4406196213425, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI73915096, Length=581, Percent_Identity=24.4406196213425, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI73915094, Length=581, Percent_Identity=24.4406196213425, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI113429326, Length=579, Percent_Identity=22.7979274611399, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI113429324, Length=580, Percent_Identity=22.9310344827586, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI109148539, Length=504, Percent_Identity=26.1904761904762, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI153266901, Length=215, Percent_Identity=26.5116279069767, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI153266885, Length=215, Percent_Identity=26.5116279069767, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1789856, Length=567, Percent_Identity=28.7477954144621, Blast_Score=191, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI72000294, Length=435, Percent_Identity=25.2873563218391, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI212646519, Length=437, Percent_Identity=25.4004576659039, Blast_Score=98, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17542894, Length=464, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17506189, Length=450, Percent_Identity=23.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193208247, Length=539, Percent_Identity=21.7068645640074, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193208245, Length=539, Percent_Identity=21.7068645640074, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24642670, Length=507, Percent_Identity=24.0631163708087, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24642666, Length=507, Percent_Identity=24.0631163708087, Blast_Score=100, Evalue=6e-21,
Organism=Drosophila melanogaster, GI45551474, Length=507, Percent_Identity=23.8658777120316, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI161077878, Length=508, Percent_Identity=23.8188976377953, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161077880, Length=508, Percent_Identity=23.8188976377953, Blast_Score=99, Evalue=1e-20,
Organism=Drosophila melanogaster, GI161077496, Length=458, Percent_Identity=23.1441048034935, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI18859893, Length=433, Percent_Identity=25.1732101616628, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859741, Length=518, Percent_Identity=22.007722007722, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 67678; Mature: 67678

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYALLTGAACALALAACAQTPEPAPQALEPAPVTAAPETTPAARENAAFPMTGQRPESG
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPIATRSAVVAPNGAAATAHPLATQTALDVLKAGGTAVDAAIAANAMLGLVEPTGNGIGG
CCEECCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCCCCC
DLYAIVWDPETEQLYGYNGSGRSAMDATLEDAQAKADQFKDGKSLPSYGAITVTVPGTVD
CEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCH
GWFALHEKFGQRPMADNLAPAVKYAREGAPIPEMIAWYWSRGPLRFEPAFERGELEEFAN
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHC
AKKTYFDPTPVAGSLFKNPDLANTLETIGKKGRDEFYKGVMAKDMAAYFSRIGGKLDYDD
CCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FNAHTGDWVEPICVEYRSEVKVCELGPNTQGVAALQMLEMLERFDLKSMGFGSPDAVTAM
CCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHH
VEAKRLAFADRALGYADPAFSGIDPSIFVAPGYNAKRAEAIDVTRAMPEVAPGTEITDAA
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
LRDGDTTYLTVTDKDGMMVSLIQSNYRGMGSGLVADGMGFMFQDRGELFSLDANHPNVFA
HCCCCEEEEEEECCCCCEEHHHHHCCCCCCCCHHHCCCCCEEECCCCEEEEECCCCCEEC
PGKRPFHTIIPAFAFRKDLPGCQTAATAPDLACPYEPWLSFGLMGGATQPQGHVQIITNL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHH
IDFDMGLQEAGDAARWEHDGGCEPTNALGDDCDTGTGTVMLERGLAGIADELESRGYDVA
HHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEE
CCEANYGGYQAIMRDFRSGAWIAATEMRKDGNADGY
EEECCCCHHHHHHHHHCCCCEEEEEHHCCCCCCCCC
>Mature Secondary Structure
MKYALLTGAACALALAACAQTPEPAPQALEPAPVTAAPETTPAARENAAFPMTGQRPESG
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPIATRSAVVAPNGAAATAHPLATQTALDVLKAGGTAVDAAIAANAMLGLVEPTGNGIGG
CCEECCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEECCCCCCCCC
DLYAIVWDPETEQLYGYNGSGRSAMDATLEDAQAKADQFKDGKSLPSYGAITVTVPGTVD
CEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCH
GWFALHEKFGQRPMADNLAPAVKYAREGAPIPEMIAWYWSRGPLRFEPAFERGELEEFAN
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCCCCHHHHHC
AKKTYFDPTPVAGSLFKNPDLANTLETIGKKGRDEFYKGVMAKDMAAYFSRIGGKLDYDD
CCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FNAHTGDWVEPICVEYRSEVKVCELGPNTQGVAALQMLEMLERFDLKSMGFGSPDAVTAM
CCCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHCCHHHCCCCCCHHHHHH
VEAKRLAFADRALGYADPAFSGIDPSIFVAPGYNAKRAEAIDVTRAMPEVAPGTEITDAA
HHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHH
LRDGDTTYLTVTDKDGMMVSLIQSNYRGMGSGLVADGMGFMFQDRGELFSLDANHPNVFA
HCCCCEEEEEEECCCCCEEHHHHHCCCCCCCCHHHCCCCCEEECCCCEEEEECCCCCEEC
PGKRPFHTIIPAFAFRKDLPGCQTAATAPDLACPYEPWLSFGLMGGATQPQGHVQIITNL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHHHH
IDFDMGLQEAGDAARWEHDGGCEPTNALGDDCDTGTGTVMLERGLAGIADELESRGYDVA
HHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHCCCEEE
CCEANYGGYQAIMRDFRSGAWIAATEMRKDGNADGY
EEECCCCHHHHHHHHHCCCCEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]