Click here to switch to the map view.

The map label for this gene is eamA [H]

Identifier: 114798186

GI number: 114798186

Start: 473796

End: 474698

Strand: Reverse

Name: eamA [H]

Synonym: HNE_0481

Alternate gene names: 114798186

Gene position: 474698-473796 (Counterclockwise)

Preceding gene: 114798941

Following gene: 114800083

Centisome position: 12.81

GC content: 63.34

Gene sequence:

>903_bases
ATGGCCATACGTGACTTCATCCTGCTCTGCGCTGTCTGCCTCGTCTGGGGGCTGAACCTTGTCGTCACGCGCTGGGCCGT
GGCCGACATGGCCATTCCGCCGATCTTCTTTGCCGCGCTGCGTTTCCTCGGCGTGGCGGTCTGCCTCGTGCCCTTCCTCT
TCCCGCGCCCACCCAATTTGCGCACGCTGTTCTTCGTCTCGATCATGATCGGCAGCGTCCACTTCTCGCTCCTCTTCATC
GGTCTCCAACACGCAGACGCTTCCGCTGCCGCTGTCACCGGCCAGCTCGGCGTGCCCTTCTCCACGCTGATGAGCATGCT
GTTCCTCGGAGAAGTCATCCGCTGGCGCCGCGCTATCGGCATCACGCTCGCCTTTCTGGGTGTCATCATCATCGCGCTGG
ACCCGGCAAACTTCTCGGTCTCCTTCGGCCTGCTCTACATCATCGCCTCCGCCTTCATCGGCTCGGCGGGCGGCATCGTG
ATGAAACGCATGCCGCAGATCTCCGGCCTGCGCATGCAGGCCTGGGTCGGCCTTTTCAGCTTTGCGCCGCTCTTTGCGCT
CTCCTTCGCCATCGAGGAAAACCAGCTTGCCACCTACATCGATGGCGGCTGGATGGTCTGGGCCGCCAGTGCCTTCGCCA
TCCTCGGTGTCTCCGTGTTCGGCCATTCGGCCTTCTATACGCTGCTCAAGAAGTATGACGTCTCCCTCCTCTCCCCGCTC
ACGCTGATGACCCCCATCTGGGGCGTCATCTTCGGCATTGCGCTGCTGAACGAACCGCTGACCCCGCGCCTCATCCTCGG
CGCCATCGTTTCGCTGTCGGGCGTGCTTGTCATCGCGCTCCGCCCGAACGAGAAAATGCCTGAAGCGGCCCTCGGCAAGA
AGGCCGGCGCCGGAGACTCGTGA

Upstream 100 bases:

>100_bases
GGGAAGCCAAGCAGTGCCACCCCCGCATAGCTCCCCTGCCGCCCTGACGCGGCGCGCCCCCTGCCCATTGTCACAAAACC
CTGATAGGCCCGAACCCATC

Downstream 100 bases:

>100_bases
TGGAAATCGAAGACACCCCCAGCCCGAACTTTGACGACCGCAAACACCCCGTCACCCTGCTCGTGCTCCATTATACGGGC
ATGGAAAGCGGCGAGGCCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MAIRDFILLCAVCLVWGLNLVVTRWAVADMAIPPIFFAALRFLGVAVCLVPFLFPRPPNLRTLFFVSIMIGSVHFSLLFI
GLQHADASAAAVTGQLGVPFSTLMSMLFLGEVIRWRRAIGITLAFLGVIIIALDPANFSVSFGLLYIIASAFIGSAGGIV
MKRMPQISGLRMQAWVGLFSFAPLFALSFAIEENQLATYIDGGWMVWAASAFAILGVSVFGHSAFYTLLKKYDVSLLSPL
TLMTPIWGVIFGIALLNEPLTPRLILGAIVSLSGVLVIALRPNEKMPEAALGKKAGAGDS

Sequences:

>Translated_300_residues
MAIRDFILLCAVCLVWGLNLVVTRWAVADMAIPPIFFAALRFLGVAVCLVPFLFPRPPNLRTLFFVSIMIGSVHFSLLFI
GLQHADASAAAVTGQLGVPFSTLMSMLFLGEVIRWRRAIGITLAFLGVIIIALDPANFSVSFGLLYIIASAFIGSAGGIV
MKRMPQISGLRMQAWVGLFSFAPLFALSFAIEENQLATYIDGGWMVWAASAFAILGVSVFGHSAFYTLLKKYDVSLLSPL
TLMTPIWGVIFGIALLNEPLTPRLILGAIVSLSGVLVIALRPNEKMPEAALGKKAGAGDS
>Mature_299_residues
AIRDFILLCAVCLVWGLNLVVTRWAVADMAIPPIFFAALRFLGVAVCLVPFLFPRPPNLRTLFFVSIMIGSVHFSLLFIG
LQHADASAAAVTGQLGVPFSTLMSMLFLGEVIRWRRAIGITLAFLGVIIIALDPANFSVSFGLLYIIASAFIGSAGGIVM
KRMPQISGLRMQAWVGLFSFAPLFALSFAIEENQLATYIDGGWMVWAASAFAILGVSVFGHSAFYTLLKKYDVSLLSPLT
LMTPIWGVIFGIALLNEPLTPRLILGAIVSLSGVLVIALRPNEKMPEAALGKKAGAGDS

Specific function: May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O- acetyl-L-serine (OAS)), and for other amino acids and their metabolites [H]

COG id: COG0697

COG function: function code GER; Permeases of the drug/metabolite transporter (DMT) superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DUF6 domains [H]

Homologues:

Organism=Escherichia coli, GI87081929, Length=289, Percent_Identity=26.9896193771626, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000620 [H]

Pfam domain/function: PF00892 DUF6 [H]

EC number: NA

Molecular weight: Translated: 32239; Mature: 32108

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIRDFILLCAVCLVWGLNLVVTRWAVADMAIPPIFFAALRFLGVAVCLVPFLFPRPPNL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
RTLFFVSIMIGSVHFSLLFIGLQHADASAAAVTGQLGVPFSTLMSMLFLGEVIRWRRAIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ITLAFLGVIIIALDPANFSVSFGLLYIIASAFIGSAGGIVMKRMPQISGLRMQAWVGLFS
HHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHH
FAPLFALSFAIEENQLATYIDGGWMVWAASAFAILGVSVFGHSAFYTLLKKYDVSLLSPL
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
TLMTPIWGVIFGIALLNEPLTPRLILGAIVSLSGVLVIALRPNEKMPEAALGKKAGAGDS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure 
AIRDFILLCAVCLVWGLNLVVTRWAVADMAIPPIFFAALRFLGVAVCLVPFLFPRPPNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
RTLFFVSIMIGSVHFSLLFIGLQHADASAAAVTGQLGVPFSTLMSMLFLGEVIRWRRAIG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ITLAFLGVIIIALDPANFSVSFGLLYIIASAFIGSAGGIVMKRMPQISGLRMQAWVGLFS
HHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHH
FAPLFALSFAIEENQLATYIDGGWMVWAASAFAILGVSVFGHSAFYTLLKKYDVSLLSPL
HHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
TLMTPIWGVIFGIALLNEPLTPRLILGAIVSLSGVLVIALRPNEKMPEAALGKKAGAGDS
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEEECCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8383113; 9097039; 9278503; 10844694 [H]