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The map label for this gene is 114798159

Identifier: 114798159

GI number: 114798159

Start: 2127283

End: 2128452

Strand: Direct

Name: 114798159

Synonym: HNE_2052

Alternate gene names: NA

Gene position: 2127283-2128452 (Clockwise)

Preceding gene: 114799698

Following gene: 114797350

Centisome position: 57.42

GC content: 62.48

Gene sequence:

>1170_bases
ATGCCAGTGCCGACACCATTCAAAGTTCAGGTTCCAGACGCAAAGCTTGCCGAGATCCGGGCGCGGGTGGAGGGGTATCG
GTGGTTCCCTGCCCCGGCCAATGAGCAGGGCTTTGCCTATGGCATGTCGACCGAGGTGATGAAGGACATTCAGCGTTATT
GGCTGGAGACGTATGACTGGCGGGCGGCCGAGGCCGAGCTGAACCGGTGGCCACAATTTAGGGCTGAGGTGGACGGGCTG
CCGATCCATTTTGTGCATGTGGTGGGGGAGGCAAAGGGGAAGCGTCCGCTGCTGATCACGCATGGCTGGCCGGGCAGCAT
CTATGAATTCTGGCAGGCGATCGGGCCGCTGGCCTTCCCGTCCCAGCATGGCGGCAAGGCGGAGGATGCGTTTGATCTCG
TGATCCCGTCCCTGCCCGGTTATGGCTTTTCCGGCAAGCCTGCCTCGCCGCTGGGCCAGCGGGCGACGGCGGCGATGTGG
GACACGCTGATGCGGGAGGTGCTGGGCTATTCCAGCTATCTGGCGCAGGGCGGGGATTGGGGGTCGATGGTCACGTCCTG
GATCGGCAAGAACCATGGGCTGAGCGAGGGCAAAGGCGGGGCGAAGGCGATCCATCTCAATATGATGGGCTTCCGGCCGA
CACCGGCAGTTCCTCAGACGGCGGAGGAAACGAAATGGCTGCAGCATTCGCAAATGATGATGCAGGCAGAGGGCGCTTAC
CTGATGCAGCAGGCGACCAAGCCGCAAACGCTGGCGATGGCGCTGATGGATTCGCCGATGGGCACGGCGGCGTGGATTCT
GGAGAAGTTTCACGGCTGGAGCGATCTTACGGAGCGCGGCCTTTTTGAGGTTTACACGCGCGACCAGCTGCTGACGAATG
TGATGATCTACCTCGTCAATGACGCGATTGCGACGAGCGTCTGGTATTATAACGCCCTCTTCCAGGAAGGCGGCAATGGC
CTGCCCGAGGGCGAGCGCTGCGAGACGCCGACGGCTTTTGCGAGCTATCCAGGTGAACGCTACATCGTGGCGCCGCCGAG
GAGCTGGGCGGACCGGGCGTATAATATTACTCGGTGGACGGACATGCCGCGCGGGGGGCATTTTGCGGCGATGGAAGCGC
CGGAGGTTTATGTGGAAGATGTGCGGGCTTGGGCGCGGGAGGTGGGGTAA

Upstream 100 bases:

>100_bases
ACTTCATGGGCGAGGGGTTAAGGGGTCTTGCCGCTGGGGGATGGCTTAGCTGGAACGAGGGTGTGGGCTAGGCTCGTCTG
GCCAGATGAGGGGACATGCC

Downstream 100 bases:

>100_bases
TTCCATCTGTACGCCGCGCTTTCCATAGTGCGCCGGGTAATGGGTTGCACCTTCAGCTGACCCGACTTACGATTTCTGGT
GTGGAACAACTATGGTAAGC

Product: epoxide hydrolase

Products: NA

Alternate protein names: Epoxide hydratase [H]

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MPVPTPFKVQVPDAKLAEIRARVEGYRWFPAPANEQGFAYGMSTEVMKDIQRYWLETYDWRAAEAELNRWPQFRAEVDGL
PIHFVHVVGEAKGKRPLLITHGWPGSIYEFWQAIGPLAFPSQHGGKAEDAFDLVIPSLPGYGFSGKPASPLGQRATAAMW
DTLMREVLGYSSYLAQGGDWGSMVTSWIGKNHGLSEGKGGAKAIHLNMMGFRPTPAVPQTAEETKWLQHSQMMMQAEGAY
LMQQATKPQTLAMALMDSPMGTAAWILEKFHGWSDLTERGLFEVYTRDQLLTNVMIYLVNDAIATSVWYYNALFQEGGNG
LPEGERCETPTAFASYPGERYIVAPPRSWADRAYNITRWTDMPRGGHFAAMEAPEVYVEDVRAWAREVG

Sequences:

>Translated_389_residues
MPVPTPFKVQVPDAKLAEIRARVEGYRWFPAPANEQGFAYGMSTEVMKDIQRYWLETYDWRAAEAELNRWPQFRAEVDGL
PIHFVHVVGEAKGKRPLLITHGWPGSIYEFWQAIGPLAFPSQHGGKAEDAFDLVIPSLPGYGFSGKPASPLGQRATAAMW
DTLMREVLGYSSYLAQGGDWGSMVTSWIGKNHGLSEGKGGAKAIHLNMMGFRPTPAVPQTAEETKWLQHSQMMMQAEGAY
LMQQATKPQTLAMALMDSPMGTAAWILEKFHGWSDLTERGLFEVYTRDQLLTNVMIYLVNDAIATSVWYYNALFQEGGNG
LPEGERCETPTAFASYPGERYIVAPPRSWADRAYNITRWTDMPRGGHFAAMEAPEVYVEDVRAWAREVG
>Mature_388_residues
PVPTPFKVQVPDAKLAEIRARVEGYRWFPAPANEQGFAYGMSTEVMKDIQRYWLETYDWRAAEAELNRWPQFRAEVDGLP
IHFVHVVGEAKGKRPLLITHGWPGSIYEFWQAIGPLAFPSQHGGKAEDAFDLVIPSLPGYGFSGKPASPLGQRATAAMWD
TLMREVLGYSSYLAQGGDWGSMVTSWIGKNHGLSEGKGGAKAIHLNMMGFRPTPAVPQTAEETKWLQHSQMMMQAEGAYL
MQQATKPQTLAMALMDSPMGTAAWILEKFHGWSDLTERGLFEVYTRDQLLTNVMIYLVNDAIATSVWYYNALFQEGGNGL
PEGERCETPTAFASYPGERYIVAPPRSWADRAYNITRWTDMPRGGHFAAMEAPEVYVEDVRAWAREVG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

Organism=Homo sapiens, GI4503583, Length=408, Percent_Identity=33.578431372549, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI209862837, Length=408, Percent_Identity=33.578431372549, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17564944, Length=419, Percent_Identity=34.8448687350835, Blast_Score=241, Evalue=6e-64,
Organism=Caenorhabditis elegans, GI193207462, Length=410, Percent_Identity=26.8292682926829, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI20130139, Length=409, Percent_Identity=32.2738386308068, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24655327, Length=406, Percent_Identity=30.2955665024631, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI19922580, Length=415, Percent_Identity=29.1566265060241, Blast_Score=164, Evalue=8e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 43553; Mature: 43422

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVPTPFKVQVPDAKLAEIRARVEGYRWFPAPANEQGFAYGMSTEVMKDIQRYWLETYDW
CCCCCCCEEECCCHHHHHHHHHHCCEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHCCC
RAAEAELNRWPQFRAEVDGLPIHFVHVVGEAKGKRPLLITHGWPGSIYEFWQAIGPLAFP
CHHHHHHHCCCHHHHHCCCCCEEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCCCC
SQHGGKAEDAFDLVIPSLPGYGFSGKPASPLGQRATAAMWDTLMREVLGYSSYLAQGGDW
CCCCCCCCCHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
GSMVTSWIGKNHGLSEGKGGAKAIHLNMMGFRPTPAVPQTAEETKWLQHSQMMMQAEGAY
HHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
LMQQATKPQTLAMALMDSPMGTAAWILEKFHGWSDLTERGLFEVYTRDQLLTNVMIYLVN
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DAIATSVWYYNALFQEGGNGLPEGERCETPTAFASYPGERYIVAPPRSWADRAYNITRWT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHCEEEEECC
DMPRGGHFAAMEAPEVYVEDVRAWAREVG
CCCCCCCEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PVPTPFKVQVPDAKLAEIRARVEGYRWFPAPANEQGFAYGMSTEVMKDIQRYWLETYDW
CCCCCCEEECCCHHHHHHHHHHCCEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHCCC
RAAEAELNRWPQFRAEVDGLPIHFVHVVGEAKGKRPLLITHGWPGSIYEFWQAIGPLAFP
CHHHHHHHCCCHHHHHCCCCCEEEEEEEECCCCCCCEEEECCCCCHHHHHHHHHCCCCCC
SQHGGKAEDAFDLVIPSLPGYGFSGKPASPLGQRATAAMWDTLMREVLGYSSYLAQGGDW
CCCCCCCCCHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
GSMVTSWIGKNHGLSEGKGGAKAIHLNMMGFRPTPAVPQTAEETKWLQHSQMMMQAEGAY
HHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCHH
LMQQATKPQTLAMALMDSPMGTAAWILEKFHGWSDLTERGLFEVYTRDQLLTNVMIYLVN
HHHHCCCCHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHH
DAIATSVWYYNALFQEGGNGLPEGERCETPTAFASYPGERYIVAPPRSWADRAYNITRWT
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCCCCEEEEECCHHHHHHCEEEEECC
DMPRGGHFAAMEAPEVYVEDVRAWAREVG
CCCCCCCEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226695 [H]