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The map label for this gene is erpA2 [H]

Identifier: 114799698

GI number: 114799698

Start: 2126627

End: 2126968

Strand: Direct

Name: erpA2 [H]

Synonym: HNE_2051

Alternate gene names: 114799698

Gene position: 2126627-2126968 (Clockwise)

Preceding gene: 114799719

Following gene: 114798159

Centisome position: 57.4

GC content: 57.89

Gene sequence:

>342_bases
ATGACCGAGACCATTGCCCCGGATGTGACACTGACTGCTTCTGCTGCGAAGCGGATTAATGCGATTCTCGCCAAACAGGA
CGGCGCCGCCTATCTGCGCGTGTCCGTAGAAGGTGGGGGATGTTCGGGCTTTTCCTACAAGTTTGACTTCGCGCCTGCTG
TAAATGCGGATGATGTCGTGATCGAACGCGACGGGGCAAGTGTGCTGATCGACGAGATGAGCCTGGAGTTTCTGCAGGGG
TCGGAGATCGACTTTTCCACAGAGCTGATCGGCGCGGCGTTCAAGATCAAGAACCCGAACGCGACCGCGGCCTGTGGCTG
CGGGACCAGTTTTTCGGTCTGA

Upstream 100 bases:

>100_bases
CCGAGGGGGCCTCCTCAAAAAAGCGCCCACGGCTGTCTTCGTGACGTGTTGCGTAAGGGGCTCTCTTTTCCATTCAGGAA
TTCGTCCTTATGTTAGGCCC

Downstream 100 bases:

>100_bases
AAAAGCTCTAAAAAACTCCAACGGTTCCTCCAACGAGGGGGCAAAAACTCCAACGCGGTTGGAGTTTTTTTGTGTGGCAG
TTTTGGTCACACGGGGGACA

Product: iron-sulfur cluster assembly accessory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 112

Protein sequence:

>113_residues
MTETIAPDVTLTASAAKRINAILAKQDGAAYLRVSVEGGGCSGFSYKFDFAPAVNADDVVIERDGASVLIDEMSLEFLQG
SEIDFSTELIGAAFKIKNPNATAACGCGTSFSV

Sequences:

>Translated_113_residues
MTETIAPDVTLTASAAKRINAILAKQDGAAYLRVSVEGGGCSGFSYKFDFAPAVNADDVVIERDGASVLIDEMSLEFLQG
SEIDFSTELIGAAFKIKNPNATAACGCGTSFSV
>Mature_112_residues
TETIAPDVTLTASAAKRINAILAKQDGAAYLRVSVEGGGCSGFSYKFDFAPAVNADDVVIERDGASVLIDEMSLEFLQGS
EIDFSTELIGAAFKIKNPNATAACGCGTSFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG [H]

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family [H]

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=45.7943925233645, Blast_Score=104, Evalue=2e-23,
Organism=Homo sapiens, GI52426768, Length=105, Percent_Identity=31.4285714285714, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786351, Length=114, Percent_Identity=41.2280701754386, Blast_Score=103, Evalue=2e-24,
Organism=Escherichia coli, GI1788877, Length=105, Percent_Identity=41.9047619047619, Blast_Score=92, Evalue=7e-21,
Organism=Escherichia coli, GI1787974, Length=105, Percent_Identity=40, Blast_Score=91, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=38.8888888888889, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146411, Length=105, Percent_Identity=38.0952380952381, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI193209025, Length=105, Percent_Identity=38.0952380952381, Blast_Score=85, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6323001, Length=105, Percent_Identity=38.0952380952381, Blast_Score=80, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325324, Length=135, Percent_Identity=31.1111111111111, Blast_Score=74, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24649697, Length=106, Percent_Identity=46.2264150943396, Blast_Score=94, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24642263, Length=105, Percent_Identity=37.1428571428571, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063 [H]

Pfam domain/function: PF01521 Fe-S_biosyn [H]

EC number: NA

Molecular weight: Translated: 11732; Mature: 11601

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETIAPDVTLTASAAKRINAILAKQDGAAYLRVSVEGGGCSGFSYKFDFAPAVNADDVV
CCCCCCCCEEEEHHHHHHHEEEEECCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCEE
IERDGASVLIDEMSLEFLQGSEIDFSTELIGAAFKIKNPNATAACGCGTSFSV
EEECCCEEEEECCEEEECCCCCCCCCHHEEEEEEEECCCCCCEEECCCCCCCC
>Mature Secondary Structure 
TETIAPDVTLTASAAKRINAILAKQDGAAYLRVSVEGGGCSGFSYKFDFAPAVNADDVV
CCCCCCCEEEEHHHHHHHEEEEECCCCCEEEEEEECCCCCCCCCEEEECCCCCCCCCEE
IERDGASVLIDEMSLEFLQGSEIDFSTELIGAAFKIKNPNATAACGCGTSFSV
EEECCCEEEEECCEEEECCCCCCCCCHHEEEEEEEECCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA