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The map label for this gene is dnaQ [H]

Identifier: 114798147

GI number: 114798147

Start: 3104

End: 3802

Strand: Direct

Name: dnaQ [H]

Synonym: HNE_0005

Alternate gene names: 114798147

Gene position: 3104-3802 (Clockwise)

Preceding gene: 114797191

Following gene: 114799709

Centisome position: 0.08

GC content: 61.52

Gene sequence:

>699_bases
ATGACAGAACGCGTCCGGGAAATCGCCTTCGACACCGAGACCACAGGCCTCAACCCGAATGAGGGCGACAGGATCATCGA
GATCGGCGCGGTTGAGATGATCAATCACATCCCGACCGGCAAGACCTTCCGGCGCCTGATCAATCCGGGCATGGCCGTCT
CCGAAGCCACAATTCGCATCACCGGCATTACGGACGACCATCTTCGCGACAAACCGCCTTTCGAGCATCCCGACATTATT
GATGCGTTTCTGGAATTTACCGGCGACGCCATCATCGTGGCCCACAATGCCAGCTTTGACCGCGGCTTCCTGAATATGGA
ACTGCAACGCTGCGGGCGCGACATCATTCCGGAAGACCGCTGGGTCGATACCGTTCAGATGGCGCGGAAACGCTATCCCG
GCGCCCCGGCCAGCCTGGACGCGCTCTGCAAACGGTTCGACATTTCTCTGGAAAGCCGCACCTTCCACGGGGCGCTGCTC
GATAGTCAGCTCTTGGCGAGTGTCTATCTGGAGCTGCTGGGTGGTCGCGCCCGCGCGTTCAGTTTCGAACCCACGCTGGG
AGGGGAGGGCTACCAACGCCCCGCAGCCCGGCAGCGCCCGGCGCCGCTTGCTTCTCTGGTGACAGATGCAGAGCGCGCCG
CCCATGCCGAGCTTGTTGAAAAGCTTGGGGCAGACGCGCTCTGGAAAACCTTGCCCTGA

Upstream 100 bases:

>100_bases
CAGATTTCATCGTATCGACGGCCCATGGTTTTGACTTTGCACGCGACCATGTCCGCGCCATTATCGCCCTGATGAAGCGA
ATCGCTGACGGAGAGACCCC

Downstream 100 bases:

>100_bases
GGGCGGGTCAGCTCGCGCCGCCATTGCCGTTCTGCGCGCGCTCTGCCGCGCGGCGGTATTGCGACTGATAGAGAGCCACA
AAATCAACGGGGTCGATGAG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MTERVREIAFDTETTGLNPNEGDRIIEIGAVEMINHIPTGKTFRRLINPGMAVSEATIRITGITDDHLRDKPPFEHPDII
DAFLEFTGDAIIVAHNASFDRGFLNMELQRCGRDIIPEDRWVDTVQMARKRYPGAPASLDALCKRFDISLESRTFHGALL
DSQLLASVYLELLGGRARAFSFEPTLGGEGYQRPAARQRPAPLASLVTDAERAAHAELVEKLGADALWKTLP

Sequences:

>Translated_232_residues
MTERVREIAFDTETTGLNPNEGDRIIEIGAVEMINHIPTGKTFRRLINPGMAVSEATIRITGITDDHLRDKPPFEHPDII
DAFLEFTGDAIIVAHNASFDRGFLNMELQRCGRDIIPEDRWVDTVQMARKRYPGAPASLDALCKRFDISLESRTFHGALL
DSQLLASVYLELLGGRARAFSFEPTLGGEGYQRPAARQRPAPLASLVTDAERAAHAELVEKLGADALWKTLP
>Mature_231_residues
TERVREIAFDTETTGLNPNEGDRIIEIGAVEMINHIPTGKTFRRLINPGMAVSEATIRITGITDDHLRDKPPFEHPDIID
AFLEFTGDAIIVAHNASFDRGFLNMELQRCGRDIIPEDRWVDTVQMARKRYPGAPASLDALCKRFDISLESRTFHGALLD
SQLLASVYLELLGGRARAFSFEPTLGGEGYQRPAARQRPAPLASLVTDAERAAHAELVEKLGADALWKTLP

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=242, Percent_Identity=40.495867768595, Blast_Score=161, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25736; Mature: 25604

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERVREIAFDTETTGLNPNEGDRIIEIGAVEMINHIPTGKTFRRLINPGMAVSEATIRI
CCHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHHCCCCEEECEEEEE
TGITDDHLRDKPPFEHPDIIDAFLEFTGDAIIVAHNASFDRGFLNMELQRCGRDIIPEDR
ECCCHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCH
WVDTVQMARKRYPGAPASLDALCKRFDISLESRTFHGALLDSQLLASVYLELLGGRARAF
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
SFEPTLGGEGYQRPAARQRPAPLASLVTDAERAAHAELVEKLGADALWKTLP
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
TERVREIAFDTETTGLNPNEGDRIIEIGAVEMINHIPTGKTFRRLINPGMAVSEATIRI
CHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHHHHHCCCCHHHHHHHCCCCEEECEEEEE
TGITDDHLRDKPPFEHPDIIDAFLEFTGDAIIVAHNASFDRGFLNMELQRCGRDIIPEDR
ECCCHHHHCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCH
WVDTVQMARKRYPGAPASLDALCKRFDISLESRTFHGALLDSQLLASVYLELLGGRARAF
HHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
SFEPTLGGEGYQRPAARQRPAPLASLVTDAERAAHAELVEKLGADALWKTLP
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]