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The map label for this gene is coaE [H]

Identifier: 114797191

GI number: 114797191

Start: 2499

End: 3107

Strand: Direct

Name: coaE [H]

Synonym: HNE_0004

Alternate gene names: 114797191

Gene position: 2499-3107 (Clockwise)

Preceding gene: 114799600

Following gene: 114798147

Centisome position: 0.07

GC content: 61.41

Gene sequence:

>609_bases
ATGATCATCCTTGGGCTGACTGGCTCTATAGGCATGGGAAAATCTGCCACCGCGAACCTTTTCAAGGACGCGGGCATACC
GGTTTATGATGCCGACGCGGCCGTTCATGCGCTCTATGCGGAAGGCGGCGCAGCCGTGGCCCCGCTTGAGGACGCCTTTC
CGGGCGTCGCCCATAAAGGCGCCATTGACCGGCAGAAACTGCGCACCCGCGTGCTCGACGATCCCGAGGCCATGAAGCGG
CTGGAAGGAATCGTCCATCCGCTCGCCGGCGAAGCGCAGCTGGATTTCCGGCGCCGCGCAAAGGATGACGGCGCGCAGTT
TGCGGTTCTCGATATTCCTCTGCTGTTTGAAACGGGCGGCAACCGGCACTGTACCTACACGCTGGTTGTTTCTGCCCCCG
CTGATATTCAGCGGGCTCGCGTGCTCGCCCGGCCGGGAATGACCGAAGAGGTGTTTGAGTCGATTCTTGCCCGTCAGATG
CCGGACGCCGACAAGCGAGCGCGGGCAGATTTCATCGTATCGACGGCCCATGGTTTTGACTTTGCACGCGACCATGTCCG
CGCCATTATCGCCCTGATGAAGCGAATCGCTGACGGAGAGACCCCATGA

Upstream 100 bases:

>100_bases
TGGTTGCTCAGGCAGCTATCAGCTTCGAACACTGGTTTGGTATCAAGCCGGACATGGCCGAGGCGCATGCCCGGTGCCGT
AAGCTTGTGGAGGCCACATC

Downstream 100 bases:

>100_bases
CAGAACGCGTCCGGGAAATCGCCTTCGACACCGAGACCACAGGCCTCAACCCGAATGAGGGCGACAGGATCATCGAGATC
GGCGCGGTTGAGATGATCAA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MIILGLTGSIGMGKSATANLFKDAGIPVYDADAAVHALYAEGGAAVAPLEDAFPGVAHKGAIDRQKLRTRVLDDPEAMKR
LEGIVHPLAGEAQLDFRRRAKDDGAQFAVLDIPLLFETGGNRHCTYTLVVSAPADIQRARVLARPGMTEEVFESILARQM
PDADKRARADFIVSTAHGFDFARDHVRAIIALMKRIADGETP

Sequences:

>Translated_202_residues
MIILGLTGSIGMGKSATANLFKDAGIPVYDADAAVHALYAEGGAAVAPLEDAFPGVAHKGAIDRQKLRTRVLDDPEAMKR
LEGIVHPLAGEAQLDFRRRAKDDGAQFAVLDIPLLFETGGNRHCTYTLVVSAPADIQRARVLARPGMTEEVFESILARQM
PDADKRARADFIVSTAHGFDFARDHVRAIIALMKRIADGETP
>Mature_202_residues
MIILGLTGSIGMGKSATANLFKDAGIPVYDADAAVHALYAEGGAAVAPLEDAFPGVAHKGAIDRQKLRTRVLDDPEAMKR
LEGIVHPLAGEAQLDFRRRAKDDGAQFAVLDIPLLFETGGNRHCTYTLVVSAPADIQRARVLARPGMTEEVFESILARQM
PDADKRARADFIVSTAHGFDFARDHVRAIIALMKRIADGETP

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI110227607, Length=199, Percent_Identity=29.6482412060301, Blast_Score=80, Evalue=9e-16,
Organism=Homo sapiens, GI110227605, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227603, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI110227601, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI205277394, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI191252797, Length=189, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI191252795, Length=189, Percent_Identity=26.984126984127, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786292, Length=207, Percent_Identity=30.9178743961353, Blast_Score=82, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554944, Length=199, Percent_Identity=27.6381909547739, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI25143409, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=197, Percent_Identity=27.9187817258883, Blast_Score=82, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24644728, Length=197, Percent_Identity=27.9187817258883, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658602, Length=202, Percent_Identity=29.7029702970297, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21773; Mature: 21773

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILGLTGSIGMGKSATANLFKDAGIPVYDADAAVHALYAEGGAAVAPLEDAFPGVAHKG
CEEEEECCCCCCCCCHHHHHHHHCCCCEEECCHHHHHHHHCCCCEECCHHHHCCCCCCCC
AIDRQKLRTRVLDDPEAMKRLEGIVHPLAGEAQLDFRRRAKDDGAQFAVLDIPLLFETGG
CCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEEEEEECCC
NRHCTYTLVVSAPADIQRARVLARPGMTEEVFESILARQMPDADKRARADFIVSTAHGFD
CCEEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHEEEEECCCCH
FARDHVRAIIALMKRIADGETP
HHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIILGLTGSIGMGKSATANLFKDAGIPVYDADAAVHALYAEGGAAVAPLEDAFPGVAHKG
CEEEEECCCCCCCCCHHHHHHHHCCCCEEECCHHHHHHHHCCCCEECCHHHHCCCCCCCC
AIDRQKLRTRVLDDPEAMKRLEGIVHPLAGEAQLDFRRRAKDDGAQFAVLDIPLLFETGG
CCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCEEEEEEEEEEEECCC
NRHCTYTLVVSAPADIQRARVLARPGMTEEVFESILARQMPDADKRARADFIVSTAHGFD
CCEEEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHEEEEECCCCH
FARDHVRAIIALMKRIADGETP
HHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]