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The map label for this gene is thiL [H]

Identifier: 114798043

GI number: 114798043

Start: 1168608

End: 1169561

Strand: Direct

Name: thiL [H]

Synonym: HNE_1157

Alternate gene names: 114798043

Gene position: 1168608-1169561 (Clockwise)

Preceding gene: 114799515

Following gene: 114797162

Centisome position: 31.54

GC content: 65.93

Gene sequence:

>954_bases
ATGGCCGAGAAGGACTGGATACGCCAGTATTTCGCGCCGCTGGCCAAGGCGCCGGGCGCGGCGGGTCTGACCGACGATAC
GGCTGAAATTTCAAAGGGTTACGGGCCTCTCATTGCGACGGTGGACGCGATGGTGGAGGGCGTGCACTTTTTTGCTGACG
ATCCGGTCGAGACGATTGCGCGCAAGCTGGTGCGGGTGAATGTGTCGGATATTCTGGGCTCTGGCGCGGTTCCGCGGGAG
GCGCTTTTGACCCTCGGATGGCCCCAGGCGGGGCGCAATCCGGGACAGATCGGGACATTTGCGGACAGTTTCGGGACAGA
ACTGGACAGGTGGGGCATCCTCTTGGCTGGCGGCGACACGGTGATGACACCGGGGGGCCTCTTCCTGTCGCTGACCCTGA
CAGGCGAATGCCTGGGGCCTGCGCCGGTGCGCCGGGGCGGGGGCAAGGCGGGGGATGACGTCTGGGTGACCGGGGAGATC
GGCGCGGCAAGGCGGGGGTATCTGTGGAAAACGCAAGGGCTGGGCGAGGCCGGCTGGCTGAACGCGTTGCAGGTGCCGGA
GCTGCCTCCGCTTGAGGCGGCGGGGCTGATTTCCGCCCATGCGAGCGCGGCGATGGATATTTCCGACGGGCTGCTGGGCG
ACCTGTCCAGCCTGGCGGCGGCCAGCGGGCTGGGCGCGCAAATCGACCTCGACCAGGTGCCGTTTGCAGGCGGGGCGGCG
AGCCTTGAGGAAATGATCGATCTTTCGAGCTGGGGCGATGATTATCAGCTGCTGTTTGCGGCGCCGCCTCAAGCGGCTGG
TTTCATTCAGGATTTTGGATTGCGGGTGACCCGGATCGGGCGCCTGGCCGAGGGGGCGGGGCTTGTGGCCTCTCACTGTG
GAAAACCCGTTAACTTGCCGGAAACTCTCGCCTTCGAGCATGGCCGAGTCGGTGGTCCTGCCGCTCGCTCCTGA

Upstream 100 bases:

>100_bases
TGTGCTTCAGGAGCTGGAGGGCATGTCGCCCGCCGAGCTGCGGGCGCAGCGGCGGGAGCGGTTCTATGCCATTGGCCGTG
AGGGCCTTTAAGGGCCTCTG

Downstream 100 bases:

>100_bases
CGCGATGCATCTTGCGCGCGTCCGGCCCGGCTGGCAGGCAAGTCGGTCTAAGAAGAAAAAAAGACCAGACCGGAATCAAT
CCGGCTGAGTTTTCTCGGGG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MAEKDWIRQYFAPLAKAPGAAGLTDDTAEISKGYGPLIATVDAMVEGVHFFADDPVETIARKLVRVNVSDILGSGAVPRE
ALLTLGWPQAGRNPGQIGTFADSFGTELDRWGILLAGGDTVMTPGGLFLSLTLTGECLGPAPVRRGGGKAGDDVWVTGEI
GAARRGYLWKTQGLGEAGWLNALQVPELPPLEAAGLISAHASAAMDISDGLLGDLSSLAAASGLGAQIDLDQVPFAGGAA
SLEEMIDLSSWGDDYQLLFAAPPQAAGFIQDFGLRVTRIGRLAEGAGLVASHCGKPVNLPETLAFEHGRVGGPAARS

Sequences:

>Translated_317_residues
MAEKDWIRQYFAPLAKAPGAAGLTDDTAEISKGYGPLIATVDAMVEGVHFFADDPVETIARKLVRVNVSDILGSGAVPRE
ALLTLGWPQAGRNPGQIGTFADSFGTELDRWGILLAGGDTVMTPGGLFLSLTLTGECLGPAPVRRGGGKAGDDVWVTGEI
GAARRGYLWKTQGLGEAGWLNALQVPELPPLEAAGLISAHASAAMDISDGLLGDLSSLAAASGLGAQIDLDQVPFAGGAA
SLEEMIDLSSWGDDYQLLFAAPPQAAGFIQDFGLRVTRIGRLAEGAGLVASHCGKPVNLPETLAFEHGRVGGPAARS
>Mature_316_residues
AEKDWIRQYFAPLAKAPGAAGLTDDTAEISKGYGPLIATVDAMVEGVHFFADDPVETIARKLVRVNVSDILGSGAVPREA
LLTLGWPQAGRNPGQIGTFADSFGTELDRWGILLAGGDTVMTPGGLFLSLTLTGECLGPAPVRRGGGKAGDDVWVTGEIG
AARRGYLWKTQGLGEAGWLNALQVPELPPLEAAGLISAHASAAMDISDGLLGDLSSLAAASGLGAQIDLDQVPFAGGAAS
LEEMIDLSSWGDDYQLLFAAPPQAAGFIQDFGLRVTRIGRLAEGAGLVASHCGKPVNLPETLAFEHGRVGGPAARS

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=293, Percent_Identity=30.7167235494881, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 32711; Mature: 32580

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKDWIRQYFAPLAKAPGAAGLTDDTAEISKGYGPLIATVDAMVEGVHFFADDPVETIA
CCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
RKLVRVNVSDILGSGAVPREALLTLGWPQAGRNPGQIGTFADSFGTELDRWGILLAGGDT
HHHHHCCHHHHHCCCCCCHHHHEEECCCCCCCCCCCCCCHHHHHCCCHHHCEEEEECCCE
VMTPGGLFLSLTLTGECLGPAPVRRGGGKAGDDVWVTGEIGAARRGYLWKTQGLGEAGWL
EECCCCEEEEEEEECCCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCC
NALQVPELPPLEAAGLISAHASAAMDISDGLLGDLSSLAAASGLGAQIDLDQVPFAGGAA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHH
SLEEMIDLSSWGDDYQLLFAAPPQAAGFIQDFGLRVTRIGRLAEGAGLVASHCGKPVNLP
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCCCCC
ETLAFEHGRVGGPAARS
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AEKDWIRQYFAPLAKAPGAAGLTDDTAEISKGYGPLIATVDAMVEGVHFFADDPVETIA
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHH
RKLVRVNVSDILGSGAVPREALLTLGWPQAGRNPGQIGTFADSFGTELDRWGILLAGGDT
HHHHHCCHHHHHCCCCCCHHHHEEECCCCCCCCCCCCCCHHHHHCCCHHHCEEEEECCCE
VMTPGGLFLSLTLTGECLGPAPVRRGGGKAGDDVWVTGEIGAARRGYLWKTQGLGEAGWL
EECCCCEEEEEEEECCCCCCCCHHCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCC
NALQVPELPPLEAAGLISAHASAAMDISDGLLGDLSSLAAASGLGAQIDLDQVPFAGGAA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHH
SLEEMIDLSSWGDDYQLLFAAPPQAAGFIQDFGLRVTRIGRLAEGAGLVASHCGKPVNLP
HHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCHHHHHHHHHCCCCHHHHHCCCCCCCC
ETLAFEHGRVGGPAARS
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]