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The map label for this gene is ppa [H]

Identifier: 114798033

GI number: 114798033

Start: 11123

End: 11662

Strand: Reverse

Name: ppa [H]

Synonym: HNE_0016

Alternate gene names: 114798033

Gene position: 11662-11123 (Counterclockwise)

Preceding gene: 114799488

Following gene: 114800535

Centisome position: 0.31

GC content: 59.81

Gene sequence:

>540_bases
ATGGACCTTTCGAAAATTTCCGCCGGCAACAATCCGCCTGACGACATCAACGTTCTGATCGAAGTGCCGCTGGGCGGGGA
TGCGATCAAATACGAGATCGACAAGGCCTCCGGCGCGATGTTCGTGGACCGCTTCCTCTACACCGAGATGCGCTATCCCT
GTAATTACGGGTTTGTGCCGCACACGCTGAGCCTCGATGGCGATCCGATCGATGTGATGGTGGTGGGCAACCGCCCGCTG
GTGCCGGGCTGTGTGCTGCGCGTGCGCCCGGTCGGCGTGCTGATGATGACTGACGACAAGGGCCAGGACGAGAAGATCCT
CGCCGTGCCCCACCCGAAACTGACGGGCTATTACGACAAGATCTCGACCTATCACGACCTGCCGCAGACGCTTTGCGACA
AGATCCAGCACTTCTTCGAGCACTATAAGGATCTGGAAAAAGGCAAATGGACCCGCATCGATGGCTGGCATGGCATCGAG
AAGGCGCGCGAGCTGATCCGCGACGCCGTTGCCCGCGAGCAGGCAAACCTGAAGGGCTGA

Upstream 100 bases:

>100_bases
TCGGGGTCTGCCTACTCATTACCCTTGACCTGAAGCCTGCGGCAGTTCATCCGGGCGCCGAACTTTCCTGACCTCCCACA
GCGAAGCATGTGAGCCTCCC

Downstream 100 bases:

>100_bases
TCTGTCGGGATTTGTCCAAAGATGACCGAAGCTGGCCTGGAGGGTGCACCCTTCCAGGCCAGTTCTGTTTCTAGGGCGCC
ACGATTTCGAACCGCTGGGA

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MDLSKISAGNNPPDDINVLIEVPLGGDAIKYEIDKASGAMFVDRFLYTEMRYPCNYGFVPHTLSLDGDPIDVMVVGNRPL
VPGCVLRVRPVGVLMMTDDKGQDEKILAVPHPKLTGYYDKISTYHDLPQTLCDKIQHFFEHYKDLEKGKWTRIDGWHGIE
KARELIRDAVAREQANLKG

Sequences:

>Translated_179_residues
MDLSKISAGNNPPDDINVLIEVPLGGDAIKYEIDKASGAMFVDRFLYTEMRYPCNYGFVPHTLSLDGDPIDVMVVGNRPL
VPGCVLRVRPVGVLMMTDDKGQDEKILAVPHPKLTGYYDKISTYHDLPQTLCDKIQHFFEHYKDLEKGKWTRIDGWHGIE
KARELIRDAVAREQANLKG
>Mature_179_residues
MDLSKISAGNNPPDDINVLIEVPLGGDAIKYEIDKASGAMFVDRFLYTEMRYPCNYGFVPHTLSLDGDPIDVMVVGNRPL
VPGCVLRVRPVGVLMMTDDKGQDEKILAVPHPKLTGYYDKISTYHDLPQTLCDKIQHFFEHYKDLEKGKWTRIDGWHGIE
KARELIRDAVAREQANLKG

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=174, Percent_Identity=56.8965517241379, Blast_Score=211, Evalue=2e-56,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20214; Mature: 20214

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSKISAGNNPPDDINVLIEVPLGGDAIKYEIDKASGAMFVDRFLYTEMRYPCNYGFVP
CCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
HTLSLDGDPIDVMVVGNRPLVPGCVLRVRPVGVLMMTDDKGQDEKILAVPHPKLTGYYDK
CEEECCCCCEEEEEECCCCCCCCEEEEEECCEEEEEECCCCCCCEEEEECCCCCCCHHHH
ISTYHDLPQTLCDKIQHFFEHYKDLEKGKWTRIDGWHGIEKARELIRDAVAREQANLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLSKISAGNNPPDDINVLIEVPLGGDAIKYEIDKASGAMFVDRFLYTEMRYPCNYGFVP
CCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCC
HTLSLDGDPIDVMVVGNRPLVPGCVLRVRPVGVLMMTDDKGQDEKILAVPHPKLTGYYDK
CEEECCCCCEEEEEECCCCCCCCEEEEEECCEEEEEECCCCCCCEEEEECCCCCCCHHHH
ISTYHDLPQTLCDKIQHFFEHYKDLEKGKWTRIDGWHGIEKARELIRDAVAREQANLKG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]