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The map label for this gene is ycaN [C]

Identifier: 114799488

GI number: 114799488

Start: 11772

End: 12671

Strand: Reverse

Name: ycaN [C]

Synonym: HNE_0017

Alternate gene names: 114799488

Gene position: 12671-11772 (Counterclockwise)

Preceding gene: 114800166

Following gene: 114798033

Centisome position: 0.34

GC content: 58.22

Gene sequence:

>900_bases
ATGATTCCAGATCTCAATGCTCTTTCGGTCTTTGCTCTGGTTGCCGAGGAGCGCAATTTTCGCGCTGCTGCTGATCGGCT
GGGCGTTACACGGTCTGCTGTCAGCCAGACCATCCGGAAGTTGGAGGAAACGCTGGGGATCGCGTTGGTTCAGCGTACAA
CGCGCAGTGTCAGCCTGACCGAGGCGGGCGAGCGTCTCTATGTCGAGGCGGCCCCCGCGCTTGGAGACTTGCGCAGGGCG
GTGGAACTGACAGGCAGCCTGTCTGGCCGTCCGCAAGGGCAACTGAGATTGGCTGTTTCCTCTATCGCTGAACATTTTCT
GGGCGGAGCGCTTCTCTCCACTTTCGCCAAGGCCCATCCCGGCATCCAGATGGATGTGTTGGTGACAGATGAGGAATTTG
ACATCGTCGCGGAAGGCTATGATGCGGCGGTGCGGCTGGGCGAGGTGATTGAGCAGGATATGATCGCGGTGCCGGTTTCC
GCCGAGCAGCGCCAACTGGCCGTTGGCGCGCCTTCCTATCTGGCAGAGGCAGGGGCACCGGCCCATCCACGCGATCTGGT
GCATCATCGCTGTGTGGGCTGGCGGTCAGCGCCAAAACAGGCACCCTATCGCTGGGAATTTGCAGAGCGTGATGGCCGCG
AATTCAGCGTTTCTGTGTCACCGGAAATCACCACAAACGATATGGCGTTGATGATAAAATTGGCGGTGGCTGGCGCCGGT
ATCACCTTCGGCATGGAAGAAAGTTTCTGGCCGGCGATGAAGAGAGGAGAACTTGTGGCAGTTCTGGAAGACTTCTGTCC
TCATTTTTCCGGCTTCTATCTCTATTATCCGAGCCGCCGCAATCTTGCGCCAAAACTTCGAGCGCTGATCGACCATTTGC
GAAAAGCGCCGCCTCGTTAA

Upstream 100 bases:

>100_bases
GATCCCTGCCCTGCCTAGGGCGACTGCCATTCAGATAGACACGCTGGATTGTTGCGATAAGTTACCCATTCTTTTCCACT
TTGGTGACTTTATCTAATCA

Downstream 100 bases:

>100_bases
AGTATTCGTTCGGGGTCTGCCTACTCATTACCCTTGACCTGAAGCCTGCGGCAGTTCATCCGGGCGCCGAACTTTCCTGA
CCTCCCACAGCGAAGCATGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MIPDLNALSVFALVAEERNFRAAADRLGVTRSAVSQTIRKLEETLGIALVQRTTRSVSLTEAGERLYVEAAPALGDLRRA
VELTGSLSGRPQGQLRLAVSSIAEHFLGGALLSTFAKAHPGIQMDVLVTDEEFDIVAEGYDAAVRLGEVIEQDMIAVPVS
AEQRQLAVGAPSYLAEAGAPAHPRDLVHHRCVGWRSAPKQAPYRWEFAERDGREFSVSVSPEITTNDMALMIKLAVAGAG
ITFGMEESFWPAMKRGELVAVLEDFCPHFSGFYLYYPSRRNLAPKLRALIDHLRKAPPR

Sequences:

>Translated_299_residues
MIPDLNALSVFALVAEERNFRAAADRLGVTRSAVSQTIRKLEETLGIALVQRTTRSVSLTEAGERLYVEAAPALGDLRRA
VELTGSLSGRPQGQLRLAVSSIAEHFLGGALLSTFAKAHPGIQMDVLVTDEEFDIVAEGYDAAVRLGEVIEQDMIAVPVS
AEQRQLAVGAPSYLAEAGAPAHPRDLVHHRCVGWRSAPKQAPYRWEFAERDGREFSVSVSPEITTNDMALMIKLAVAGAG
ITFGMEESFWPAMKRGELVAVLEDFCPHFSGFYLYYPSRRNLAPKLRALIDHLRKAPPR
>Mature_299_residues
MIPDLNALSVFALVAEERNFRAAADRLGVTRSAVSQTIRKLEETLGIALVQRTTRSVSLTEAGERLYVEAAPALGDLRRA
VELTGSLSGRPQGQLRLAVSSIAEHFLGGALLSTFAKAHPGIQMDVLVTDEEFDIVAEGYDAAVRLGEVIEQDMIAVPVS
AEQRQLAVGAPSYLAEAGAPAHPRDLVHHRCVGWRSAPKQAPYRWEFAERDGREFSVSVSPEITTNDMALMIKLAVAGAG
ITFGMEESFWPAMKRGELVAVLEDFCPHFSGFYLYYPSRRNLAPKLRALIDHLRKAPPR

Specific function: May have a role in the regulation of oprD expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=35.0515463917526, Blast_Score=199, Evalue=1e-52,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=34.8432055749129, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=29.3918918918919, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI87081978, Length=299, Percent_Identity=31.7725752508361, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1789639, Length=290, Percent_Identity=29.3103448275862, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=29.757785467128, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=28.3737024221453, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1789173, Length=275, Percent_Identity=28.7272727272727, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788706, Length=305, Percent_Identity=26.2295081967213, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=200, Percent_Identity=25.5, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788748, Length=119, Percent_Identity=34.453781512605, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI157672245, Length=174, Percent_Identity=31.0344827586207, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786448, Length=287, Percent_Identity=24.7386759581882, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787601, Length=123, Percent_Identity=30.0813008130081, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786508, Length=175, Percent_Identity=28, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32722; Mature: 32722

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPDLNALSVFALVAEERNFRAAADRLGVTRSAVSQTIRKLEETLGIALVQRTTRSVSLT
CCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
EAGERLYVEAAPALGDLRRAVELTGSLSGRPQGQLRLAVSSIAEHFLGGALLSTFAKAHP
CCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIQMDVLVTDEEFDIVAEGYDAAVRLGEVIEQDMIAVPVSAEQRQLAVGAPSYLAEAGAP
CCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCHHHHHCCCC
AHPRDLVHHRCVGWRSAPKQAPYRWEFAERDGREFSVSVSPEITTNDMALMIKLAVAGAG
CCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCCCHHHHHEEHHHHCCC
ITFGMEESFWPAMKRGELVAVLEDFCPHFSGFYLYYPSRRNLAPKLRALIDHLRKAPPR
EEECCCCHHCHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIPDLNALSVFALVAEERNFRAAADRLGVTRSAVSQTIRKLEETLGIALVQRTTRSVSLT
CCCCCHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
EAGERLYVEAAPALGDLRRAVELTGSLSGRPQGQLRLAVSSIAEHFLGGALLSTFAKAHP
CCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIQMDVLVTDEEFDIVAEGYDAAVRLGEVIEQDMIAVPVSAEQRQLAVGAPSYLAEAGAP
CCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHEEECCCCCCCEEECCCCHHHHHCCCC
AHPRDLVHHRCVGWRSAPKQAPYRWEFAERDGREFSVSVSPEITTNDMALMIKLAVAGAG
CCHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEEEEECCCCCCCHHHHHEEHHHHCCC
ITFGMEESFWPAMKRGELVAVLEDFCPHFSGFYLYYPSRRNLAPKLRALIDHLRKAPPR
EEECCCCHHCHHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]