Click here to switch to the map view.

The map label for this gene is rmlA1 [C]

Identifier: 114798017

GI number: 114798017

Start: 1612283

End: 1613005

Strand: Reverse

Name: rmlA1 [C]

Synonym: HNE_1579

Alternate gene names: 114798017

Gene position: 1613005-1612283 (Counterclockwise)

Preceding gene: 114799011

Following gene: 114797441

Centisome position: 43.54

GC content: 55.05

Gene sequence:

>723_bases
ATGAAAGCCATTCTTCTGAGCGCCGGCCGCGGCTCTCGCCTTCTGCCTTTGACCGAATCCCGTCCGAAATGCCTGCTACC
GGTTCAGGCCACGACGCTGCTTGGGTATCAGCTCGACACGCTCGAAGCCGCAGGCATCCGCGATGTGACTGTGGTGACCG
GCTTTCTTCCCAATCTTGTCGAGGCAGAGCTTGCTCGTCGCACGGGTCCGCTCAAGGCCATGCCGTTCTTCAACCCCTTC
TTTCAGGTAGCGGATAATCTGGCGAGCTGCTGGATGGTCCGGGAACAGATGGATGATGATTTTCTCCTTATCAATGGAGA
CACTCTGTTTTCCCAGGAGCTAATCGAGAAGGTTATCGCCGCGCCACCGGCCCCAATTCTGGTGACCATTGACCAGAAGG
CCGTTTATGATCAGGACGATATGAAAGTCACCCTGTCCGGGACCACGCTGACAGGCATAGGGAAAACTCTTCTCCCGCCA
GACGTTCACGCAGAATCCATTGGCATCCTGCGTTTTGCAGGCAAAGGCCCGGAGGTCTTCCGGGAAAAGCTGGAGCAGAT
GATGCGCACTCAAGACGGCATCCACGCATGGTTTCTCAAGGCAATTAACGCCATTGCAAGCGCCGGCAGCGGCAGTGTCG
AAACTGTCCTGATCAAAGGTCATCTCTGGGCTGAAGTTGATACAGTCGAAGATTTCAATGCGTTGAAAGAGATCGGATTT
TGA

Upstream 100 bases:

>100_bases
CCTCCGGACTCAGGAAAGCGGCGCAGAAACTCCACATAACCATTGCTGACTTCAACACAGTTGAAATTGGATTCCTTTCA
GACAAAGTGACTGTTTCCGC

Downstream 100 bases:

>100_bases
AATCAGGATGGAGACAGGCAATCCATCAATGACGCCCCTTCTCAATCCAAGCGTCCTGGTTTTGGCGATTGGTGAGGCGC
ATCAACTGCTCCATATTCTT

Product: nucleotidyltransferase family protein

Products: dTDPglucose; Diphosphate [C]

Alternate protein names: Nucleotidyltransferase Family Protein; Sugar Nucleotidyltransferase; Glucose-1-Phosphate Cytidylyltransferase; LicC-Like Protein; ADP-Glucose Pyrophosphorylase; Nucleotidyl Transferase WchZ; Phosphoenolpyruvate Phosphomutase; Cholinephosphate Cytidylyltransferase/Choline Kinase; Sugar-1-Phosphate Nucleotidylyltransferase; Sugar Metabolism Cluster Protein; Cholinephosphate Cytidylyltransferase; LicC Protein; Phosphoenolpyruvate Mutase; Sugar Nucleotidyltransferase-Like Protein; Choline Kinase

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKAILLSAGRGSRLLPLTESRPKCLLPVQATTLLGYQLDTLEAAGIRDVTVVTGFLPNLVEAELARRTGPLKAMPFFNPF
FQVADNLASCWMVREQMDDDFLLINGDTLFSQELIEKVIAAPPAPILVTIDQKAVYDQDDMKVTLSGTTLTGIGKTLLPP
DVHAESIGILRFAGKGPEVFREKLEQMMRTQDGIHAWFLKAINAIASAGSGSVETVLIKGHLWAEVDTVEDFNALKEIGF

Sequences:

>Translated_240_residues
MKAILLSAGRGSRLLPLTESRPKCLLPVQATTLLGYQLDTLEAAGIRDVTVVTGFLPNLVEAELARRTGPLKAMPFFNPF
FQVADNLASCWMVREQMDDDFLLINGDTLFSQELIEKVIAAPPAPILVTIDQKAVYDQDDMKVTLSGTTLTGIGKTLLPP
DVHAESIGILRFAGKGPEVFREKLEQMMRTQDGIHAWFLKAINAIASAGSGSVETVLIKGHLWAEVDTVEDFNALKEIGF
>Mature_240_residues
MKAILLSAGRGSRLLPLTESRPKCLLPVQATTLLGYQLDTLEAAGIRDVTVVTGFLPNLVEAELARRTGPLKAMPFFNPF
FQVADNLASCWMVREQMDDDFLLINGDTLFSQELIEKVIAAPPAPILVTIDQKAVYDQDDMKVTLSGTTLTGIGKTLLPP
DVHAESIGILRFAGKGPEVFREKLEQMMRTQDGIHAWFLKAINAIASAGSGSVETVLIKGHLWAEVDTVEDFNALKEIGF

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1213

COG function: function code M; Predicted sugar nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24 [C]

Molecular weight: Translated: 26211; Mature: 26211

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILLSAGRGSRLLPLTESRPKCLLPVQATTLLGYQLDTLEAAGIRDVTVVTGFLPNLV
CCEEEEECCCCCEEECCCCCCCCEEEEEHHHHHHCEEECCCCCCCCCHHHHHHHHHHHHH
EAELARRTGPLKAMPFFNPFFQVADNLASCWMVREQMDDDFLLINGDTLFSQELIEKVIA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHC
APPAPILVTIDQKAVYDQDDMKVTLSGTTLTGIGKTLLPPDVHAESIGILRFAGKGPEVF
CCCCCEEEEECCHHCCCCCCCEEEEECCEEECCCCCCCCCCCCCCCEEEEEECCCCHHHH
REKLEQMMRTQDGIHAWFLKAINAIASAGSGSVETVLIKGHLWAEVDTVEDFNALKEIGF
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECEEEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MKAILLSAGRGSRLLPLTESRPKCLLPVQATTLLGYQLDTLEAAGIRDVTVVTGFLPNLV
CCEEEEECCCCCEEECCCCCCCCEEEEEHHHHHHCEEECCCCCCCCCHHHHHHHHHHHHH
EAELARRTGPLKAMPFFNPFFQVADNLASCWMVREQMDDDFLLINGDTLFSQELIEKVIA
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHC
APPAPILVTIDQKAVYDQDDMKVTLSGTTLTGIGKTLLPPDVHAESIGILRFAGKGPEVF
CCCCCEEEEECCHHCCCCCCCEEEEECCEEECCCCCCCCCCCCCCCEEEEEECCCCHHHH
REKLEQMMRTQDGIHAWFLKAINAIASAGSGSVETVLIKGHLWAEVDTVEDFNALKEIGF
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECEEEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; D-Glucose 1-phosphate; H+ [C]

Specific reaction: dTTP + D-Glucose 1-phosphate + H+ --> dTDPglucose + Diphosphate [C]

General reaction: Nucleotidyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA