BacMap

Definition	Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession	NC_008358
Length	3,705,021

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The map label for this gene is fabG [H]

Identifier: 114798016

GI number: 114798016

Start: 2914580

End: 2915353

Strand: Reverse

Name: fabG [H]

Synonym: HNE_2754

Alternate gene names: 114798016

Gene position: 2915353-2914580 (Counterclockwise)

Preceding gene: 114797801

Following gene: 114798996

Centisome position: 78.69

GC content: 66.28

Gene sequence:

>774_bases
ATGGATCTCGGCCTCACAGACAAAATCGTGTTCATCGCCGGCGCCAGCCGGGGCATCGGCCACGGCATCGCCCGCAGCCT
GCTGGAAGAGGGTGCCAAGGTTGCCCTCACCGCGCGCGGCGCTGAAGCGCTGGAGGCCACCCGCGCCGATTTCGCTGCCG
AATTTGGCAGTGACAAAGTCTGGTCCTTCGCCGGCGACCTGACCCAGACCGCCGGTATCGAAGCTGCGCTCACCGCCTGC
GACGCAGATTTCGGCCAGATCAACGCCGCCGTCGCCAATGTCGGCCTTTCGCCCTCGCCGCTGGGCGTCGATGTGTCCGA
TGATGACTGGCAGGCCGGCCTCGATCAGAACCTCAACTCCGCCTTCCGCCTCGCGCGCGGCGCCATCCCGCGCATCTCGA
AAGCGGGCGGGGGCAGTTTCCTCTTCATCTCCTCCATCGCCGGCCTCGCCGCGCTGGGCACGCCGCTGATCTACGGCGCC
ACCAAGGCGGCAGTAAATCACCTCTCCACCTCGATTGCCCGTTTCACGGCCGACACGAACGTCCGTGTAAACACTATCGC
GCCCGGCAACATCATCTTCGAAGGCAGCACCTGGGAGAAAAACGCCAACGGCCCGCGCGGCGACGCCTGGGCCCGCTGGA
TACGCCGCGAAGTCCCCATGAAACGCTTCGGCACGCCGCGCGAAATCGGCGACACCGCCGCCTTCCTCCTCTCCGAACGG
GCCAGTTTCATCAATGGCGAAGTCATCGCCGTAGACGGCGGCCAGACGCGCTGA

Upstream 100 bases:

>100_bases
CTGCCAATATCGGGGCTGCATTGGCCTCGCGCGGAGGAAGGGCTGGTCATCTTCCCCCGCCTCGGTCAGCATGCGCGCCA
CATAGGGAAGGAAAAACATC

Downstream 100 bases:

>100_bases
GCGCGTAAAACCTCTCATACGGTTGGAGCTCCGTTGGAGTTTTTCTGGAGTTTTCCGGAAAAAAACTCCAACGGCGCGCG
CCCCTCAGCGTGCCCCACCC

Product: NAD dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MDLGLTDKIVFIAGASRGIGHGIARSLLEEGAKVALTARGAEALEATRADFAAEFGSDKVWSFAGDLTQTAGIEAALTAC
DADFGQINAAVANVGLSPSPLGVDVSDDDWQAGLDQNLNSAFRLARGAIPRISKAGGGSFLFISSIAGLAALGTPLIYGA
TKAAVNHLSTSIARFTADTNVRVNTIAPGNIIFEGSTWEKNANGPRGDAWARWIRREVPMKRFGTPREIGDTAAFLLSER
ASFINGEVIAVDGGQTR

Sequences:

>Translated_257_residues
MDLGLTDKIVFIAGASRGIGHGIARSLLEEGAKVALTARGAEALEATRADFAAEFGSDKVWSFAGDLTQTAGIEAALTAC
DADFGQINAAVANVGLSPSPLGVDVSDDDWQAGLDQNLNSAFRLARGAIPRISKAGGGSFLFISSIAGLAALGTPLIYGA
TKAAVNHLSTSIARFTADTNVRVNTIAPGNIIFEGSTWEKNANGPRGDAWARWIRREVPMKRFGTPREIGDTAAFLLSER
ASFINGEVIAVDGGQTR
>Mature_257_residues
MDLGLTDKIVFIAGASRGIGHGIARSLLEEGAKVALTARGAEALEATRADFAAEFGSDKVWSFAGDLTQTAGIEAALTAC
DADFGQINAAVANVGLSPSPLGVDVSDDDWQAGLDQNLNSAFRLARGAIPRISKAGGGSFLFISSIAGLAALGTPLIYGA
TKAAVNHLSTSIARFTADTNVRVNTIAPGNIIFEGSTWEKNANGPRGDAWARWIRREVPMKRFGTPREIGDTAAFLLSER
ASFINGEVIAVDGGQTR

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.3846153846154, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=27.4193548387097, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI32483357, Length=257, Percent_Identity=28.7937743190661, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=30.4123711340206, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031737, Length=274, Percent_Identity=27.7372262773723, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=191, Percent_Identity=32.4607329842932, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=25.0996015936255, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI15277342, Length=266, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503301, Length=252, Percent_Identity=29.3650793650794, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI66933014, Length=153, Percent_Identity=24.8366013071895, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI31542939, Length=252, Percent_Identity=25, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787335, Length=251, Percent_Identity=33.4661354581673, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=29.296875, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790717, Length=255, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=29.0697674418605, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=29.5275590551181, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=28.3464566929134, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=31.3513513513514, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=27.734375, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=24.609375, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788459, Length=251, Percent_Identity=25.4980079681275, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=23.9382239382239, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787545, Length=259, Percent_Identity=25.8687258687259, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787526, Length=188, Percent_Identity=27.6595744680851, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=31.1023622047244, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=32.4324324324324, Blast_Score=103, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=31.5384615384615, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=31.2267657992565, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=30.6818181818182, Blast_Score=97, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=27.7777777777778, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=265, Percent_Identity=27.9245283018868, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=30.7984790874525, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=29.811320754717, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=30.5660377358491, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=264, Percent_Identity=28.4090909090909, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.1044776119403, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=30.6513409961686, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=256, Percent_Identity=27.34375, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=29.368029739777, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17536025, Length=264, Percent_Identity=29.1666666666667, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=28.740157480315, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=261, Percent_Identity=28.3524904214559, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=29.1338582677165, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=28.4615384615385, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=28.2945736434109, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=248, Percent_Identity=25.8064516129032, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=255, Percent_Identity=27.843137254902, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561272, Length=244, Percent_Identity=29.9180327868852, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=32.2916666666667, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6322227, Length=206, Percent_Identity=28.1553398058252, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324126, Length=256, Percent_Identity=26.171875, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6322226, Length=185, Percent_Identity=28.1081081081081, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=31.25, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355319, Length=255, Percent_Identity=28.6274509803922, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28571526, Length=252, Percent_Identity=29.3650793650794, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643142, Length=255, Percent_Identity=27.0588235294118, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24644339, Length=251, Percent_Identity=25.8964143426295, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=27.4131274131274, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=29.1828793774319, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 26778; Mature: 26778

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLGLTDKIVFIAGASRGIGHGIARSLLEEGAKVALTARGAEALEATRADFAAEFGSDKV
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCH
WSFAGDLTQTAGIEAALTACDADFGQINAAVANVGLSPSPLGVDVSDDDWQAGLDQNLNS
HHHHCCHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCHHH
AFRLARGAIPRISKAGGGSFLFISSIAGLAALGTPLIYGATKAAVNHLSTSIARFTADTN
HHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
VRVNTIAPGNIIFEGSTWEKNANGPRGDAWARWIRREVPMKRFGTPREIGDTAAFLLSER
EEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHH
ASFINGEVIAVDGGQTR
HHHHCCEEEEECCCCCC
>Mature Secondary Structure
MDLGLTDKIVFIAGASRGIGHGIARSLLEEGAKVALTARGAEALEATRADFAAEFGSDKV
CCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHCCCCCH
WSFAGDLTQTAGIEAALTACDADFGQINAAVANVGLSPSPLGVDVSDDDWQAGLDQNLNS
HHHHCCHHHHCCHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCHHH
AFRLARGAIPRISKAGGGSFLFISSIAGLAALGTPLIYGATKAAVNHLSTSIARFTADTN
HHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCC
VRVNTIAPGNIIFEGSTWEKNANGPRGDAWARWIRREVPMKRFGTPREIGDTAAFLLSER
EEEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHH
ASFINGEVIAVDGGQTR
HHHHCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]