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The map label for this gene is hfq

Identifier: 114797999

GI number: 114797999

Start: 2081180

End: 2081428

Strand: Reverse

Name: hfq

Synonym: HNE_2006

Alternate gene names: 114797999

Gene position: 2081428-2081180 (Counterclockwise)

Preceding gene: 114797385

Following gene: 114799526

Centisome position: 56.18

GC content: 57.83

Gene sequence:

>249_bases
ATGTCCGCCGATAAGAAGCAGAACCTCCAGGACACATTCCTCAATGCAGTCCGCAAATCGCGTACGCCGCTCACCGTCTT
CCTCGTAAACGGCGTCAAACTTCAGGGTGTTGTCACCTGGTTTGACAACTTCTGTATCCTGCTTCGGGGCGACGGGCGCC
CGCCGCAACTGGTGTACAAGCACGCAATCTCCACCATTGCGCCAAGCGCGCCTGTCCAGCTCTTCGACGAGGAAATGGGC
GGAGACTGA

Upstream 100 bases:

>100_bases
TCCCTCAGCTTCTGGCGGGGGTAAAGGGGGAACGCCCTTGCGCAGGGGAAGCAATTTCATTAGCTGCGCAGGATAAATAA
CAAAACAAGAAAGAAAAAAG

Downstream 100 bases:

>100_bases
TTCCGAATTGACCGAAAAACTGATTGACCGCCTTCCGGCGCCGGAAATTGCCGGCGTCGTGATCCCGTGGTTCACGCCGA
GAGATCGGCCGGGCCCGGAC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 81

Protein sequence:

>82_residues
MSADKKQNLQDTFLNAVRKSRTPLTVFLVNGVKLQGVVTWFDNFCILLRGDGRPPQLVYKHAISTIAPSAPVQLFDEEMG
GD

Sequences:

>Translated_82_residues
MSADKKQNLQDTFLNAVRKSRTPLTVFLVNGVKLQGVVTWFDNFCILLRGDGRPPQLVYKHAISTIAPSAPVQLFDEEMG
GD
>Mature_81_residues
SADKKQNLQDTFLNAVRKSRTPLTVFLVNGVKLQGVVTWFDNFCILLRGDGRPPQLVYKHAISTIAPSAPVQLFDEEMGG
D

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=77, Percent_Identity=53.2467532467532, Blast_Score=88, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_HYPNA (Q0C0N8)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760705.1
- ProteinModelPortal:   Q0C0N8
- SMR:   Q0C0N8
- STRING:   Q0C0N8
- GeneID:   4289320
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_2006
- NMPDR:   fig|228405.5.peg.1932
- TIGR:   HNE_2006
- eggNOG:   COG1923
- HOGENOM:   HBG645207
- OMA:   KNTVTQM
- PhylomeDB:   Q0C0N8
- ProtClustDB:   PRK00395
- BioCyc:   HNEP81032:HNE_2006-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9106; Mature: 8974

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADKKQNLQDTFLNAVRKSRTPLTVFLVNGVKLQGVVTWFDNFCILLRGDGRPPQLVYK
CCCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHEEEECCCEEEEEECCCCCHHHHHH
HAISTIAPSAPVQLFDEEMGGD
HHHHHCCCCCCHHHHHHHCCCC
>Mature Secondary Structure 
SADKKQNLQDTFLNAVRKSRTPLTVFLVNGVKLQGVVTWFDNFCILLRGDGRPPQLVYK
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCEEEEHEEEECCCEEEEEECCCCCHHHHHH
HAISTIAPSAPVQLFDEEMGGD
HHHHHCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA