Click here to switch to the map view.

The map label for this gene is hflX [H]

Identifier: 114799526

GI number: 114799526

Start: 2079844

End: 2081172

Strand: Reverse

Name: hflX [H]

Synonym: HNE_2005

Alternate gene names: 114799526

Gene position: 2081172-2079844 (Counterclockwise)

Preceding gene: 114797999

Following gene: 114798359

Centisome position: 56.17

GC content: 64.94

Gene sequence:

>1329_bases
TTGACCGAAAAACTGATTGACCGCCTTCCGGCGCCGGAAATTGCCGGCGTCGTGATCCCGTGGTTCACGCCGAGAGATCG
GCCGGGCCCGGACCGTTTGTCCGAAACGGCCGGCCTCGTCGAGGCTTTGGGGTGTGAACTCGGTTTCATCCGCCCTGACC
ATGTCCGCCAGGTAAACTCTTCCTTCCTTCTGTCGGGCGGCCTGCTCGACCGGATGGCGGAAGATATTGAGCAGACCAAC
GCAACGCTGGCGGTGATCGACGCTTCGCTCACGCCGGTCCAGCAGCGCAACCTCGAAAAACGCCTCGGCGTGAAGGTCAT
CGACCGGACCGGGCTGATCCTCGAAATCTTCGGCCTGCGCGCGCGGACCAAAGAGGGGCGGCTTCAGGTCGAACTTGCGC
GCCTCTTGTATGAGCGCTCGCGCCTTGTGCGCACATGGACCCACCTTGAACGCCAGCGCGGCGGCGGCGGGTTCCTCTCC
GGTCCCGGCGAAAGCCAGCTGGAAGCAGACCGCCGGATGCTGGACGACAAGATCGTCCGCCTGCGCCGTGATCTCGATGA
CGTCAAACGCACCCGCGAAGTGCAGCGGCAGGGCCGCCGGCGCAGTGGCAAGCCTGTGGTGGCGCTCGTGGGCTATACCA
ACTCCGGCAAGTCCACCCTGTTCAACCGGCTCACCGGCTCTGACGTGTTCGCCAAGGATATGCCCTTCGCCACGCTCGAT
CCCACCATCCGCCGGCTCGACCTGCCGACGCTGGGCGAAGCCGCACTTATCGACACGGTCGGTTTCATCACAGACCTGCC
AACGCACCTGATCGACAGCTTCCAGGCCACGCTGGAAGAGTCGCTGCAGGCAGACCTCCTCATCCATGTCCGCGACCGCG
CAAGTGCGTCGGATATGGAGCAGGCGGAAGATGTCGCGCTGGTGCTGGAACGTCTGGAGAAAGAGTCCGGTCTTCCATTG
CCGCCGATGATCGAAGCCTGGAACAAGATGGACGCCCTCGCGCCGGAACGCGCCGAGTCGCTCACGGGCCTCGCCGCCAT
CACGGATGATCCGCCCGCCGCTGCCGTTTCGGCATTGACCGGGGAAGGGGTGGATGCCCTGCTGGCGCTGATCGAAAAAT
CCCTCCTCCGGGGACGGACAGAAATCAGCCTCACCCTGGGCCCCGCAGACGGCAAAGCCCGCGCCTGGCTCCACCAGAAC
GGCGAAGTCCTCACCGAAACCCAACGCGAGGATGGCCAGACGGACCTCACCCTGCGCCTCTCCACCGAACGCCTCGGCCA
ATTCCGCGGCGAATTCCCGGAGCAGGCGGCGGGTGTGTCGATACTCTGA

Upstream 100 bases:

>100_bases
CGCCCGCCGCAACTGGTGTACAAGCACGCAATCTCCACCATTGCGCCAAGCGCGCCTGTCCAGCTCTTCGACGAGGAAAT
GGGCGGAGACTGATTCCGAA

Downstream 100 bases:

>100_bases
AGAGGGCTTGGTTTTAGCCCCGCTCCGCCTTCTTCACCGCCTGCCAGTACGCTTCCTGCTCATCCAGACTGAGCGACGCA
AACGCCACGCCCGCGTCCGC

Product: putative GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTEKLIDRLPAPEIAGVVIPWFTPRDRPGPDRLSETAGLVEALGCELGFIRPDHVRQVNSSFLLSGGLLDRMAEDIEQTN
ATLAVIDASLTPVQQRNLEKRLGVKVIDRTGLILEIFGLRARTKEGRLQVELARLLYERSRLVRTWTHLERQRGGGGFLS
GPGESQLEADRRMLDDKIVRLRRDLDDVKRTREVQRQGRRRSGKPVVALVGYTNSGKSTLFNRLTGSDVFAKDMPFATLD
PTIRRLDLPTLGEAALIDTVGFITDLPTHLIDSFQATLEESLQADLLIHVRDRASASDMEQAEDVALVLERLEKESGLPL
PPMIEAWNKMDALAPERAESLTGLAAITDDPPAAAVSALTGEGVDALLALIEKSLLRGRTEISLTLGPADGKARAWLHQN
GEVLTETQREDGQTDLTLRLSTERLGQFRGEFPEQAAGVSIL

Sequences:

>Translated_442_residues
MTEKLIDRLPAPEIAGVVIPWFTPRDRPGPDRLSETAGLVEALGCELGFIRPDHVRQVNSSFLLSGGLLDRMAEDIEQTN
ATLAVIDASLTPVQQRNLEKRLGVKVIDRTGLILEIFGLRARTKEGRLQVELARLLYERSRLVRTWTHLERQRGGGGFLS
GPGESQLEADRRMLDDKIVRLRRDLDDVKRTREVQRQGRRRSGKPVVALVGYTNSGKSTLFNRLTGSDVFAKDMPFATLD
PTIRRLDLPTLGEAALIDTVGFITDLPTHLIDSFQATLEESLQADLLIHVRDRASASDMEQAEDVALVLERLEKESGLPL
PPMIEAWNKMDALAPERAESLTGLAAITDDPPAAAVSALTGEGVDALLALIEKSLLRGRTEISLTLGPADGKARAWLHQN
GEVLTETQREDGQTDLTLRLSTERLGQFRGEFPEQAAGVSIL
>Mature_441_residues
TEKLIDRLPAPEIAGVVIPWFTPRDRPGPDRLSETAGLVEALGCELGFIRPDHVRQVNSSFLLSGGLLDRMAEDIEQTNA
TLAVIDASLTPVQQRNLEKRLGVKVIDRTGLILEIFGLRARTKEGRLQVELARLLYERSRLVRTWTHLERQRGGGGFLSG
PGESQLEADRRMLDDKIVRLRRDLDDVKRTREVQRQGRRRSGKPVVALVGYTNSGKSTLFNRLTGSDVFAKDMPFATLDP
TIRRLDLPTLGEAALIDTVGFITDLPTHLIDSFQATLEESLQADLLIHVRDRASASDMEQAEDVALVLERLEKESGLPLP
PMIEAWNKMDALAPERAESLTGLAAITDDPPAAAVSALTGEGVDALLALIEKSLLRGRTEISLTLGPADGKARAWLHQNG
EVLTETQREDGQTDLTLRLSTERLGQFRGEFPEQAAGVSIL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=312, Percent_Identity=34.9358974358974, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI310133116, Length=299, Percent_Identity=34.7826086956522, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI310124269, Length=277, Percent_Identity=35.3790613718412, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124267, Length=277, Percent_Identity=35.3790613718412, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124171, Length=277, Percent_Identity=35.3790613718412, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI310124169, Length=277, Percent_Identity=35.3790613718412, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1790615, Length=421, Percent_Identity=41.8052256532066, Blast_Score=283, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17561038, Length=360, Percent_Identity=31.3888888888889, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24650079, Length=362, Percent_Identity=31.767955801105, Blast_Score=145, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48705; Mature: 48574

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKLIDRLPAPEIAGVVIPWFTPRDRPGPDRLSETAGLVEALGCELGFIRPDHVRQVNS
CCHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCC
SFLLSGGLLDRMAEDIEQTNATLAVIDASLTPVQQRNLEKRLGVKVIDRTGLILEIFGLR
HHEECCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHCCEEEECCCCCCHHHHCCH
ARTKEGRLQVELARLLYERSRLVRTWTHLERQRGGGGFLSGPGESQLEADRRMLDDKIVR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRRDLDDVKRTREVQRQGRRRSGKPVVALVGYTNSGKSTLFNRLTGSDVFAKDMPFATLD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHCCCCCCCCC
PTIRRLDLPTLGEAALIDTVGFITDLPTHLIDSFQATLEESLQADLLIHVRDRASASDME
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
QAEDVALVLERLEKESGLPLPPMIEAWNKMDALAPERAESLTGLAAITDDPPAAAVSALT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCEEEECCCCHHHHHHHHC
GEGVDALLALIEKSLLRGRTEISLTLGPADGKARAWLHQNGEVLTETQREDGQTDLTLRL
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEECCCCEEECCCCCCCCCEEEEEE
STERLGQFRGEFPEQAAGVSIL
CHHHHHHHHCCCCHHHCCCCCC
>Mature Secondary Structure 
TEKLIDRLPAPEIAGVVIPWFTPRDRPGPDRLSETAGLVEALGCELGFIRPDHVRQVNS
CHHHHHHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCC
SFLLSGGLLDRMAEDIEQTNATLAVIDASLTPVQQRNLEKRLGVKVIDRTGLILEIFGLR
HHEECCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHCCEEEECCCCCCHHHHCCH
ARTKEGRLQVELARLLYERSRLVRTWTHLERQRGGGGFLSGPGESQLEADRRMLDDKIVR
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LRRDLDDVKRTREVQRQGRRRSGKPVVALVGYTNSGKSTLFNRLTGSDVFAKDMPFATLD
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHCCCCCHHHCCCCCCCCC
PTIRRLDLPTLGEAALIDTVGFITDLPTHLIDSFQATLEESLQADLLIHVRDRASASDME
CHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHH
QAEDVALVLERLEKESGLPLPPMIEAWNKMDALAPERAESLTGLAAITDDPPAAAVSALT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCEEEECCCCHHHHHHHHC
GEGVDALLALIEKSLLRGRTEISLTLGPADGKARAWLHQNGEVLTETQREDGQTDLTLRL
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHEEEECCCCEEECCCCCCCCCEEEEEE
STERLGQFRGEFPEQAAGVSIL
CHHHHHHHHCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]