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The map label for this gene is yogA [H]

Identifier: 114797977

GI number: 114797977

Start: 88934

End: 89938

Strand: Direct

Name: yogA [H]

Synonym: HNE_0100

Alternate gene names: 114797977

Gene position: 88934-89938 (Clockwise)

Preceding gene: 114797267

Following gene: 114799640

Centisome position: 2.4

GC content: 62.09

Gene sequence:

>1005_bases
ATGAAAGTAGCAGCCGTCAAAAAGCCCGGCGGGCTTCAGAACCTCGTTATCGAGACGCGGGACGACCCCAAACCCAATGC
TGGTGAAGTGCTGGTTCGCGTGCGCGCCAGCTCGCTCAACTATCACGATTTCGTCGTTGTGCTCGGCGGTATCCCGACAC
CCGATGGCCGCATCCCGATGTCGGACGGGGCAGGGGAAGTCGTCGCTGTGGGCGAAGGCGTTACCAAATGGAAAGTGGGC
GACAAGGTAATCTCCCTATTCTTCCCGAGTTGGCAGTCCGGCCAGATCGAAGCGGCCGGTTTTGCCAGTGTGCCCGGCGA
CGGCGCGGATGGGTTCGGCGCCGAATTTGTCGCCGCGCCGGAAACGTCGTTCACCCGCATGCCGGCTGGCTGGAGCTTTG
AGGAGGCCGCCACGCTTCCCTGTGCTGCGCTGACTGCCTGGCGGGGCATGTTCGTTGAAACCAAGACCAAGCCTGGCGAT
TGGGTGCTGGTGCAGGGCACCGGCGGGGTCTCCATCTTCGCGCTGCAATTTGCCAAGATGGCAGGCGCCCGCGTCATCGC
CACATCGTCGTCGAATGAGAAGATGGAAAAACTCAAACAGCTCGGCGCCGATCACGTCATCAACTACAAAGACACGCCCG
AGTGGGGCCGCAAGGCGTTCGAGCTTACAGGCGGGCGCGGCGTGGATGAGGTCGTTGAGATCGGCGGCCCCGGCACGATG
GCTCAGTCGATCAATGCCTGCCGTCCGGGTGGCCATATCTCCCTGATCGGCGTTCTGACTGGCGTGTCCGGCGAGGTGCC
AACTGCGGCCCTGTTCTCGCGGAACATCACGGTTTCCGGCATTACCGTCGGCTCACGCCGCCACCAGGAAGACATGGTCG
AAGCCATTGAGGCCTCATCCATGCGTCCTGTGATCGACAGCAAATTCCCGCTGGACCAGATCGCCGCTGCCTTTGCCCAC
CAGGCCAGCCAGAAGCATTTCGGCAAGATCGTCCTGACGATCTAA

Upstream 100 bases:

>100_bases
GTGCGCCGCAAAGCCTTACGCGAGGCGAGGCTCGCCGCCTCTTGACTTCCCCAAGGGCGCTGCTCGTCCGGTCGCGCCAC
ATCCAAGGGAGGATCAGATC

Downstream 100 bases:

>100_bases
CGGCTGATAAAAACTTGAGCCTTGGGAAGCGCCCGCCTATTCGGCGGGCGTTTCTTTTATGCGCAAGTCTTCCAGAATGC
TGTCGCCGTCGGCCGTGTCA

Product: class III alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKVAAVKKPGGLQNLVIETRDDPKPNAGEVLVRVRASSLNYHDFVVVLGGIPTPDGRIPMSDGAGEVVAVGEGVTKWKVG
DKVISLFFPSWQSGQIEAAGFASVPGDGADGFGAEFVAAPETSFTRMPAGWSFEEAATLPCAALTAWRGMFVETKTKPGD
WVLVQGTGGVSIFALQFAKMAGARVIATSSSNEKMEKLKQLGADHVINYKDTPEWGRKAFELTGGRGVDEVVEIGGPGTM
AQSINACRPGGHISLIGVLTGVSGEVPTAALFSRNITVSGITVGSRRHQEDMVEAIEASSMRPVIDSKFPLDQIAAAFAH
QASQKHFGKIVLTI

Sequences:

>Translated_334_residues
MKVAAVKKPGGLQNLVIETRDDPKPNAGEVLVRVRASSLNYHDFVVVLGGIPTPDGRIPMSDGAGEVVAVGEGVTKWKVG
DKVISLFFPSWQSGQIEAAGFASVPGDGADGFGAEFVAAPETSFTRMPAGWSFEEAATLPCAALTAWRGMFVETKTKPGD
WVLVQGTGGVSIFALQFAKMAGARVIATSSSNEKMEKLKQLGADHVINYKDTPEWGRKAFELTGGRGVDEVVEIGGPGTM
AQSINACRPGGHISLIGVLTGVSGEVPTAALFSRNITVSGITVGSRRHQEDMVEAIEASSMRPVIDSKFPLDQIAAAFAH
QASQKHFGKIVLTI
>Mature_334_residues
MKVAAVKKPGGLQNLVIETRDDPKPNAGEVLVRVRASSLNYHDFVVVLGGIPTPDGRIPMSDGAGEVVAVGEGVTKWKVG
DKVISLFFPSWQSGQIEAAGFASVPGDGADGFGAEFVAAPETSFTRMPAGWSFEEAATLPCAALTAWRGMFVETKTKPGD
WVLVQGTGGVSIFALQFAKMAGARVIATSSSNEKMEKLKQLGADHVINYKDTPEWGRKAFELTGGRGVDEVVEIGGPGTM
AQSINACRPGGHISLIGVLTGVSGEVPTAALFSRNITVSGITVGSRRHQEDMVEAIEASSMRPVIDSKFPLDQIAAAFAH
QASQKHFGKIVLTI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=352, Percent_Identity=28.125, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI22538444, Length=352, Percent_Identity=28.125, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI18379349, Length=332, Percent_Identity=26.8072289156627, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI194239674, Length=315, Percent_Identity=25.0793650793651, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI13236495, Length=315, Percent_Identity=25.0793650793651, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI41872631, Length=321, Percent_Identity=26.4797507788162, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI24308257, Length=365, Percent_Identity=23.013698630137, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI194239676, Length=313, Percent_Identity=26.1980830670927, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI47519420, Length=363, Percent_Identity=24.7933884297521, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI28557745, Length=370, Percent_Identity=26.7567567567568, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI156627571, Length=353, Percent_Identity=26.0623229461756, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082125, Length=335, Percent_Identity=28.6567164179104, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081918, Length=316, Percent_Identity=27.2151898734177, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790485, Length=250, Percent_Identity=29.6, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1787863, Length=355, Percent_Identity=25.6338028169014, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=335, Percent_Identity=26.2686567164179, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=216, Percent_Identity=28.7037037037037, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=286, Percent_Identity=26.5734265734266, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562582, Length=288, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=292, Percent_Identity=28.0821917808219, Blast_Score=92, Evalue=9e-20,
Organism=Saccharomyces cerevisiae, GI6319520, Length=348, Percent_Identity=27.0114942528736, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323961, Length=291, Percent_Identity=25.7731958762887, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6319621, Length=295, Percent_Identity=26.7796610169492, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=291, Percent_Identity=25.4295532646048, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323099, Length=338, Percent_Identity=24.5562130177515, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320033, Length=290, Percent_Identity=24.8275862068966, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319955, Length=306, Percent_Identity=24.8366013071895, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322619, Length=308, Percent_Identity=25.3246753246753, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221330659, Length=223, Percent_Identity=28.6995515695067, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI19920632, Length=223, Percent_Identity=28.2511210762332, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581345, Length=223, Percent_Identity=27.8026905829596, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 35179; Mature: 35179

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAAVKKPGGLQNLVIETRDDPKPNAGEVLVRVRASSLNYHDFVVVLGGIPTPDGRIPM
CCEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEC
SDGAGEVVAVGEGVTKWKVGDKVISLFFPSWQSGQIEAAGFASVPGDGADGFGAEFVAAP
CCCCCCEEEECCCCEEEECCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEECC
ETSFTRMPAGWSFEEAATLPCAALTAWRGMFVETKTKPGDWVLVQGTGGVSIFALQFAKM
CCCCEECCCCCCHHHHCCCCHHHHHHHCCEEEEECCCCCCEEEEECCCCEEEHHHHHHHH
AGARVIATSSSNEKMEKLKQLGADHVINYKDTPEWGRKAFELTGGRGVDEVVEIGGPGTM
CCCEEEEECCCHHHHHHHHHCCCCEEECCCCCCHHCCEEEEECCCCCHHHHHCCCCCCHH
AQSINACRPGGHISLIGVLTGVSGEVPTAALFSRNITVSGITVGSRRHQEDMVEAIEASS
HHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCC
MRPVIDSKFPLDQIAAAFAHQASQKHFGKIVLTI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MKVAAVKKPGGLQNLVIETRDDPKPNAGEVLVRVRASSLNYHDFVVVLGGIPTPDGRIPM
CCEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEEECCCCCCEEEEEECCCCCCCCCEEC
SDGAGEVVAVGEGVTKWKVGDKVISLFFPSWQSGQIEAAGFASVPGDGADGFGAEFVAAP
CCCCCCEEEECCCCEEEECCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCEEEECC
ETSFTRMPAGWSFEEAATLPCAALTAWRGMFVETKTKPGDWVLVQGTGGVSIFALQFAKM
CCCCEECCCCCCHHHHCCCCHHHHHHHCCEEEEECCCCCCEEEEECCCCEEEHHHHHHHH
AGARVIATSSSNEKMEKLKQLGADHVINYKDTPEWGRKAFELTGGRGVDEVVEIGGPGTM
CCCEEEEECCCHHHHHHHHHCCCCEEECCCCCCHHCCEEEEECCCCCHHHHHCCCCCCHH
AQSINACRPGGHISLIGVLTGVSGEVPTAALFSRNITVSGITVGSRRHQEDMVEAIEASS
HHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHCCCEEEEEEEECCCCCHHHHHHHHHHCC
MRPVIDSKFPLDQIAAAFAHQASQKHFGKIVLTI
CCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]