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The map label for this gene is sodB [H]

Identifier: 114797796

GI number: 114797796

Start: 708830

End: 709492

Strand: Reverse

Name: sodB [H]

Synonym: HNE_0696

Alternate gene names: 114797796

Gene position: 709492-708830 (Counterclockwise)

Preceding gene: 114798797

Following gene: 114797080

Centisome position: 19.15

GC content: 60.03

Gene sequence:

>663_bases
GTGCGAAACCGCTTCCGAGCGAAAGAGACCAAAACGCGCAAAGAGGACACCGCCATGGCCTTCACCCTTCCCGAACTTCC
CTATGCCCGCAATGCGCTTGCCCCGCACATTTCGGAAGAGACCCTGAACTTCCACTACGGCAAGCACCATCAGGCCTATG
TGACCAACCTGAACGGCCTCGTTGAGGGCACCGACCTTGCCGGCAAATCGCTGGAAGAGATCATCAAGATTTCTGCGGCC
GACAAGTCCAAGGCCGGCATCTTCAACAACTCCGCCCAGGTGTGGAACCACACCTTCTACTGGCACTCGATGAAGCCCGG
TGGCGGCGGCAAGCCCCACGGCAAGGCAGCCGAGCTGATTGAGCGCGACCTTGGCGGCTATGACGCCTTCGTCAAAGAGT
TCAAACAGGCGGGCGCAACCCAGTTCGGTTCGGGCTGGGCGTGGCTCTCCTACAAGGGTGGCAAGCTGGTGATCTCCAAG
ACGCCGAACGCCGAAACCCCGCTGACAGAAGAGGGCACCACGCCCCTGATGACGATGGATGTTTGGGAGCACGCCTACTA
TCTGGATTACCAGAACCGCCGCCCCGATTACATCGATACCTTCCTGGGCAGCCTGGTTAACTGGGACTTCGTGAACCAGA
ACCTCGCCGACGCGGGCGCCTAA

Upstream 100 bases:

>100_bases
GAAATCCACCGGTCCTCGTCTACCCGGCGGACTCTTTTATCAATTTCTTCCCAAGGCGTTTGGGTCAGAGGTCTGGTCTC
GTTTGACATGGACCCCATAT

Downstream 100 bases:

>100_bases
GCCTTTCCTGAATTTGCACGAAATAAGAACGCCCGCCCTTCCCCGGCGGGCGTTTTTGATATAAAGGCGGCTCATCAAAC
GCTCCGGGCATGGGATTCGC

Product: superoxide dismutase, Fe

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRNRFRAKETKTRKEDTAMAFTLPELPYARNALAPHISEETLNFHYGKHHQAYVTNLNGLVEGTDLAGKSLEEIIKISAA
DKSKAGIFNNSAQVWNHTFYWHSMKPGGGGKPHGKAAELIERDLGGYDAFVKEFKQAGATQFGSGWAWLSYKGGKLVISK
TPNAETPLTEEGTTPLMTMDVWEHAYYLDYQNRRPDYIDTFLGSLVNWDFVNQNLADAGA

Sequences:

>Translated_220_residues
MRNRFRAKETKTRKEDTAMAFTLPELPYARNALAPHISEETLNFHYGKHHQAYVTNLNGLVEGTDLAGKSLEEIIKISAA
DKSKAGIFNNSAQVWNHTFYWHSMKPGGGGKPHGKAAELIERDLGGYDAFVKEFKQAGATQFGSGWAWLSYKGGKLVISK
TPNAETPLTEEGTTPLMTMDVWEHAYYLDYQNRRPDYIDTFLGSLVNWDFVNQNLADAGA
>Mature_220_residues
MRNRFRAKETKTRKEDTAMAFTLPELPYARNALAPHISEETLNFHYGKHHQAYVTNLNGLVEGTDLAGKSLEEIIKISAA
DKSKAGIFNNSAQVWNHTFYWHSMKPGGGGKPHGKAAELIERDLGGYDAFVKEFKQAGATQFGSGWAWLSYKGGKLVISK
TPNAETPLTEEGTTPLMTMDVWEHAYYLDYQNRRPDYIDTFLGSLVNWDFVNQNLADAGA

Specific function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems [H]

COG id: COG0605

COG function: function code P; Superoxide dismutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron/manganese superoxide dismutase family [H]

Homologues:

Organism=Homo sapiens, GI67782307, Length=196, Percent_Identity=39.2857142857143, Blast_Score=143, Evalue=9e-35,
Organism=Homo sapiens, GI67782305, Length=196, Percent_Identity=39.2857142857143, Blast_Score=143, Evalue=9e-35,
Organism=Homo sapiens, GI67782309, Length=194, Percent_Identity=33.5051546391753, Blast_Score=107, Evalue=8e-24,
Organism=Escherichia coli, GI1787946, Length=199, Percent_Identity=57.7889447236181, Blast_Score=236, Evalue=9e-64,
Organism=Escherichia coli, GI1790342, Length=200, Percent_Identity=47, Blast_Score=170, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI17569479, Length=200, Percent_Identity=37, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17506561, Length=201, Percent_Identity=35.3233830845771, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321796, Length=216, Percent_Identity=36.1111111111111, Blast_Score=108, Evalue=5e-25,
Organism=Drosophila melanogaster, GI17136812, Length=201, Percent_Identity=35.3233830845771, Blast_Score=124, Evalue=5e-29,

Paralogues:

None

Copy number: 2020 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 900 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001189
- InterPro:   IPR019833
- InterPro:   IPR019832
- InterPro:   IPR019831 [H]

Pfam domain/function: PF02777 Sod_Fe_C; PF00081 Sod_Fe_N [H]

EC number: =1.15.1.1 [H]

Molecular weight: Translated: 24621; Mature: 24621

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00088 SOD_MN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNRFRAKETKTRKEDTAMAFTLPELPYARNALAPHISEETLNFHYGKHHQAYVTNLNGL
CCCCCCCHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCHHHEECCCCCCEEEEECCCCE
VEGTDLAGKSLEEIIKISAADKSKAGIFNNSAQVWNHTFYWHSMKPGGGGKPHGKAAELI
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCCCHHHHHH
ERDLGGYDAFVKEFKQAGATQFGSGWAWLSYKGGKLVISKTPNAETPLTEEGTTPLMTMD
HHHCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEHH
VWEHAYYLDYQNRRPDYIDTFLGSLVNWDFVNQNLADAGA
HHHHEEEEECCCCCCCHHHHHHHHHHCHHHHCCCHHCCCC
>Mature Secondary Structure
MRNRFRAKETKTRKEDTAMAFTLPELPYARNALAPHISEETLNFHYGKHHQAYVTNLNGL
CCCCCCCHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCHHHEECCCCCCEEEEECCCCE
VEGTDLAGKSLEEIIKISAADKSKAGIFNNSAQVWNHTFYWHSMKPGGGGKPHGKAAELI
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEEEEEECCCCCCCCCCHHHHHH
ERDLGGYDAFVKEFKQAGATQFGSGWAWLSYKGGKLVISKTPNAETPLTEEGTTPLMTMD
HHHCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCCCEEEHH
VWEHAYYLDYQNRRPDYIDTFLGSLVNWDFVNQNLADAGA
HHHHEEEEECCCCCCCHHHHHHHHHHCHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]