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The map label for this gene is htrB [C]

Identifier: 114798797

GI number: 114798797

Start: 710832

End: 711809

Strand: Reverse

Name: htrB [C]

Synonym: HNE_0699

Alternate gene names: 114798797

Gene position: 711809-710832 (Counterclockwise)

Preceding gene: 114799558

Following gene: 114797796

Centisome position: 19.21

GC content: 64.83

Gene sequence:

>978_bases
ATGAACACCCAGCCCCCCCCCTCCAACCCTGGCGGCGCCTATGTCCGCCCGAAGGACATCGATAACCGCGCCACCCTCGG
CCAGCGGATCGCCTGGCGGCTGGAAACGATTGCCTGGGATCTGATTTACTGGGCGCCGATGAAAATGCTGGGGCCGGACA
AGGCGTCAGACTTCGGCGGCTGGCTGGTGAAGAAGATCGGCCCGCTTTTTTCCCAGCACAAGACAACGAAGCGCAATCTG
CGCCTTGCCTTTCCGGACTGGAGCGAGGCGCAGGTGGAAGAGACCGCCCTGGCGGCCTGGGAAAATGCCGGGCGCACGGC
GGGCGAGCTGCCCCACTTGCCGAAGATTGATCCCTACACGTCCGGCCGCGTGGAGATCATCGGGCTGGATGTGCTCGACC
AGATCAATACCAGTTGCAAGGGCGCGGTCTTTGTCTCCGGGCATTTCGCAAACTGGGAGATCATGCCGGCGGCCATCGTC
AAGCGCATTCCCCATGCGGTGATGACCTACCGTGCGCTGAACAATCCGCATATCGACAAGCGCATCGCCGACCTGCGCCA
TGATTACGGCACCGCCGTCAACGCCCCCAAGGGCATCGGCACGCGCGAGCTGATGCGGGCGCTTGCCAAGGGCGCGCCGG
TTGCGCTGATGAATGACCAGAAGTTCAATGAAGGGATTGCGGTGCCCTTCTTCGGCCACCTCGCCATGACCGCGCCGGGG
CCGACCCGGCTGGCGCTGAAATACGGCGTGCCGATTGTGCCGGTCTCAACCGTGCGCACGGGCCCTGCCCGCTTCCGTAT
CGAGTTCCACACGCCTTTCGTGCCCGAGGATACCGGTCATCCGGAGGCGGACATTGAGCGCGCCGTGCAGCGCATCACCG
CCTTCATCGAAGACCAGGTGCGCGCCCACCCCGGCCAATGGTTCTGGCAGCATCGCCGCTGGCCCAAGGAAGCCTGGCGC
GAGGCGGGGATCAGCTGA

Upstream 100 bases:

>100_bases
CGCAATCAGAAATCCTCGCCTGGCCGGTCACCGCCGTGTTCGAGGACACCGCAGCGCTTGACGCCGTGCTCGCCCCGATC
TTCAAACGCGCTGGCAAACC

Downstream 100 bases:

>100_bases
GGCGTTGGCCTACTCTGCCAGCGGGGCCGAGGCGGGATGCATCTCCGGGCCGACAGGCTCAAACCAGATGAAGGGGCCCT
GAGGCACGCTCCCAGGTGGC

Product: lipid A biosynthesis acyltransferase

Products: NA

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Acyltransferase; Acyltransferase HtrB Family; Lipid A Biosynthesis-Lipid IVA Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Bacterial Lipid A Biosynthesis Acyltransferase; Lauroyl Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily; Lipid A Biosynthesis Lauroyl Acyltransferase Protein; Lipid A Biosynthesis Acyltransferase Family; Lipid A Lauroyl Acyltransferase; Lipid A Lauroyl Acyltransferase Protein; Lipid A Acyl Transferase

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MNTQPPPSNPGGAYVRPKDIDNRATLGQRIAWRLETIAWDLIYWAPMKMLGPDKASDFGGWLVKKIGPLFSQHKTTKRNL
RLAFPDWSEAQVEETALAAWENAGRTAGELPHLPKIDPYTSGRVEIIGLDVLDQINTSCKGAVFVSGHFANWEIMPAAIV
KRIPHAVMTYRALNNPHIDKRIADLRHDYGTAVNAPKGIGTRELMRALAKGAPVALMNDQKFNEGIAVPFFGHLAMTAPG
PTRLALKYGVPIVPVSTVRTGPARFRIEFHTPFVPEDTGHPEADIERAVQRITAFIEDQVRAHPGQWFWQHRRWPKEAWR
EAGIS

Sequences:

>Translated_325_residues
MNTQPPPSNPGGAYVRPKDIDNRATLGQRIAWRLETIAWDLIYWAPMKMLGPDKASDFGGWLVKKIGPLFSQHKTTKRNL
RLAFPDWSEAQVEETALAAWENAGRTAGELPHLPKIDPYTSGRVEIIGLDVLDQINTSCKGAVFVSGHFANWEIMPAAIV
KRIPHAVMTYRALNNPHIDKRIADLRHDYGTAVNAPKGIGTRELMRALAKGAPVALMNDQKFNEGIAVPFFGHLAMTAPG
PTRLALKYGVPIVPVSTVRTGPARFRIEFHTPFVPEDTGHPEADIERAVQRITAFIEDQVRAHPGQWFWQHRRWPKEAWR
EAGIS
>Mature_325_residues
MNTQPPPSNPGGAYVRPKDIDNRATLGQRIAWRLETIAWDLIYWAPMKMLGPDKASDFGGWLVKKIGPLFSQHKTTKRNL
RLAFPDWSEAQVEETALAAWENAGRTAGELPHLPKIDPYTSGRVEIIGLDVLDQINTSCKGAVFVSGHFANWEIMPAAIV
KRIPHAVMTYRALNNPHIDKRIADLRHDYGTAVNAPKGIGTRELMRALAKGAPVALMNDQKFNEGIAVPFFGHLAMTAPG
PTRLALKYGVPIVPVSTVRTGPARFRIEFHTPFVPEDTGHPEADIERAVQRITAFIEDQVRAHPGQWFWQHRRWPKEAWR
EAGIS

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.-

Molecular weight: Translated: 36336; Mature: 36336

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQPPPSNPGGAYVRPKDIDNRATLGQRIAWRLETIAWDLIYWAPMKMLGPDKASDFGG
CCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
WLVKKIGPLFSQHKTTKRNLRLAFPDWSEAQVEETALAAWENAGRTAGELPHLPKIDPYT
HHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SGRVEIIGLDVLDQINTSCKGAVFVSGHFANWEIMPAAIVKRIPHAVMTYRALNNPHIDK
CCCEEEEEEHHHHHCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHH
RIADLRHDYGTAVNAPKGIGTRELMRALAKGAPVALMNDQKFNEGIAVPFFGHLAMTAPG
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCEEECCCC
PTRLALKYGVPIVPVSTVRTGPARFRIEFHTPFVPEDTGHPEADIERAVQRITAFIEDQV
CCEEEEECCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RAHPGQWFWQHRRWPKEAWREAGIS
HCCCCHHHHHHCCCHHHHHHHCCCC
>Mature Secondary Structure
MNTQPPPSNPGGAYVRPKDIDNRATLGQRIAWRLETIAWDLIYWAPMKMLGPDKASDFGG
CCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
WLVKKIGPLFSQHKTTKRNLRLAFPDWSEAQVEETALAAWENAGRTAGELPHLPKIDPYT
HHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
SGRVEIIGLDVLDQINTSCKGAVFVSGHFANWEIMPAAIVKRIPHAVMTYRALNNPHIDK
CCCEEEEEEHHHHHCCCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCCHHH
RIADLRHDYGTAVNAPKGIGTRELMRALAKGAPVALMNDQKFNEGIAVPFFGHLAMTAPG
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCCCCCEECCEEECCCC
PTRLALKYGVPIVPVSTVRTGPARFRIEFHTPFVPEDTGHPEADIERAVQRITAFIEDQV
CCEEEEECCCCEEEECCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
RAHPGQWFWQHRRWPKEAWREAGIS
HCCCCHHHHHHCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA