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The map label for this gene is groES

Identifier: 114797690

GI number: 114797690

Start: 2030725

End: 2031015

Strand: Direct

Name: groES

Synonym: HNE_1961

Alternate gene names: 114797690

Gene position: 2030725-2031015 (Clockwise)

Preceding gene: 114799226

Following gene: 114800428

Centisome position: 54.81

GC content: 55.33

Gene sequence:

>291_bases
ATGAAACTTCGCCCCCTCCACGACCGCGTTGTCGTGCGCCGTGTGAAAGAAGAAGAGAAAACCAAAGGCGGGATCATTAT
CCCCGATAACGCCAAGGAAAAGCCGCAGGAAGGCATCATTGTCGCCGTCGGCAATGGCGCAATCGGTGACGACAATGAGC
GCGTGCCGCTCGACGTCAAAAAAGGCGACCGCGTCCTGTTCGGCAAATGGTCCGGCACCGAAGTGAAGATCGACGGTGAA
GACCTGCTGATCATGAAGGAAAGCGACATCATGGGCATTCTGGACAAGTAA

Upstream 100 bases:

>100_bases
GCTCGGGCGAGTGCTAACAGACGCGCGCCCCAGGCTGCGCCGGCGGGATCTCCGTCAATCTCATTCACCCGAGGAAGCTT
TGATCGAAGAGGCAGTAAAG

Downstream 100 bases:

>100_bases
GTCCGGCCCCGTCCCGCTCCCTGAAACCAAGATATAAACACAAGAGGTAACTCACATGGCTGCAAAACACGTTGTTTTCG
GCGCCGAAGCCCGCGAGCGG

Product: chaperonin, 10 kDa

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKLRPLHDRVVVRRVKEEEKTKGGIIIPDNAKEKPQEGIIVAVGNGAIGDDNERVPLDVKKGDRVLFGKWSGTEVKIDGE
DLLIMKESDIMGILDK

Sequences:

>Translated_96_residues
MKLRPLHDRVVVRRVKEEEKTKGGIIIPDNAKEKPQEGIIVAVGNGAIGDDNERVPLDVKKGDRVLFGKWSGTEVKIDGE
DLLIMKESDIMGILDK
>Mature_96_residues
MKLRPLHDRVVVRRVKEEEKTKGGIIIPDNAKEKPQEGIIVAVGNGAIGDDNERVPLDVKKGDRVLFGKWSGTEVKIDGE
DLLIMKESDIMGILDK

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=41.7582417582418, Blast_Score=68, Evalue=1e-12,
Organism=Homo sapiens, GI169210012, Length=91, Percent_Identity=39.5604395604396, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=48.9583333333333, Blast_Score=87, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=42.3913043478261, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=93, Percent_Identity=33.3333333333333, Blast_Score=60, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21356029, Length=97, Percent_Identity=39.1752577319588, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21358317, Length=96, Percent_Identity=36.4583333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_HYPNA (Q0C0T1)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760662.1
- ProteinModelPortal:   Q0C0T1
- SMR:   Q0C0T1
- STRING:   Q0C0T1
- GeneID:   4287896
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1961
- NMPDR:   fig|228405.5.peg.1890
- TIGR:   HNE_1961
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- PhylomeDB:   Q0C0T1
- BioCyc:   HNEP81032:HNE_1961-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10662; Mature: 10662

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRPLHDRVVVRRVKEEEKTKGGIIIPDNAKEKPQEGIIVAVGNGAIGDDNERVPLDVK
CCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEC
KGDRVLFGKWSGTEVKIDGEDLLIMKESDIMGILDK
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEECC
>Mature Secondary Structure
MKLRPLHDRVVVRRVKEEEKTKGGIIIPDNAKEKPQEGIIVAVGNGAIGDDNERVPLDVK
CCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEC
KGDRVLFGKWSGTEVKIDGEDLLIMKESDIMGILDK
CCCEEEEECCCCCEEEECCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA