| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is cpnA [H]
Identifier: 114799226
GI number: 114799226
Start: 2026788
End: 2027606
Strand: Direct
Name: cpnA [H]
Synonym: HNE_1957
Alternate gene names: 114799226
Gene position: 2026788-2027606 (Clockwise)
Preceding gene: 114797961
Following gene: 114797690
Centisome position: 54.7
GC content: 62.76
Gene sequence:
>819_bases ATGGCATCAGTTAAAGGCAAGGTCTCAATCGTCACTGGCGGAGCGAGCGGCATAGGCCGCTCCGCTGCGCTGGTTCTGGC GCGTGAAGGCGCGGCCGTTATGGTTACCGACATCGACGAGGCTGGGGCGCAATCGGTAGCCGCCGAGATCAACAAGGCCG GCGGCAAAGCAGCTGCCATGAAGCAGGACGTGACCGACGAAGCTGTCTGGGACGGCGTATTTGCCGACACCAAGAGCCTG CTCGGCATGCCGTCCATCCTCGTCAACAATGCCGGGATCGCCATTGGCGGGGCCATCATGGACTATTCGCTGGCTGATTG GCGCAAGCAGATGGAGGTAAATACCGACAGCGTGTTTCTGGGCACCCGCGCTGCGATGCGCACGATGAAGGGCACCGGCG GATCAATCGTGAACATCTCGTCTGTGGCGGGTCTTCGCGGCGCGTCCGGAGCAAGCGCCTACTGTGCCTCCAAGGGGGCC GTGCGCCTGTTCACCAAGGCTGCCGCTATGGAATGCGCGCAGCTTGGCCTGAATATCCGCGTGAACTCGGTTCATCCCGG CATCATCGACACGCCGATCTGGCAGAAATCGCTGACCCGCATGACCGAGACGATGCAGAAAGAACAATCGGCTGTGATCA CGGCGGCCTTCGGTGGCAATGGACTGGACCCGAAAGTAATTGCGGCGGGCAGCGCGCCGATGGGGCGGCCCGGCGCGCCG GACGAGGTGGCTGAGCTGATCCTGTTCCTCGCCTCGGATGCCTCCAGCTACATCACGGGTCAGGAGCATGTTGTGGATGG CGGGCTGACAGCACGCTAG
Upstream 100 bases:
>100_bases AACACCAATAATACCCTCGCGTCAAGCGCGTTGGCTGCTGGTCTTCGGCCCAAAAGCTGGCCAGAACTGGGCAAAACATA ACATAGGTAGGGAGGACTCA
Downstream 100 bases:
>100_bases AAAGGCGTGCCATCCTTTCGTGTGTAGAGAGGCGGCGTGTCATCATACCGGCCCGAATGCAGGTGCATATCGATATCGGA ATAGCCGCACTCGTCACGAT
Product: putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 272; Mature: 271
Protein sequence:
>272_residues MASVKGKVSIVTGGASGIGRSAALVLAREGAAVMVTDIDEAGAQSVAAEINKAGGKAAAMKQDVTDEAVWDGVFADTKSL LGMPSILVNNAGIAIGGAIMDYSLADWRKQMEVNTDSVFLGTRAAMRTMKGTGGSIVNISSVAGLRGASGASAYCASKGA VRLFTKAAAMECAQLGLNIRVNSVHPGIIDTPIWQKSLTRMTETMQKEQSAVITAAFGGNGLDPKVIAAGSAPMGRPGAP DEVAELILFLASDASSYITGQEHVVDGGLTAR
Sequences:
>Translated_272_residues MASVKGKVSIVTGGASGIGRSAALVLAREGAAVMVTDIDEAGAQSVAAEINKAGGKAAAMKQDVTDEAVWDGVFADTKSL LGMPSILVNNAGIAIGGAIMDYSLADWRKQMEVNTDSVFLGTRAAMRTMKGTGGSIVNISSVAGLRGASGASAYCASKGA VRLFTKAAAMECAQLGLNIRVNSVHPGIIDTPIWQKSLTRMTETMQKEQSAVITAAFGGNGLDPKVIAAGSAPMGRPGAP DEVAELILFLASDASSYITGQEHVVDGGLTAR >Mature_271_residues ASVKGKVSIVTGGASGIGRSAALVLAREGAAVMVTDIDEAGAQSVAAEINKAGGKAAAMKQDVTDEAVWDGVFADTKSLL GMPSILVNNAGIAIGGAIMDYSLADWRKQMEVNTDSVFLGTRAAMRTMKGTGGSIVNISSVAGLRGASGASAYCASKGAV RLFTKAAAMECAQLGLNIRVNSVHPGIIDTPIWQKSLTRMTETMQKEQSAVITAAFGGNGLDPKVIAAGSAPMGRPGAPD EVAELILFLASDASSYITGQEHVVDGGLTAR
Specific function: Reduces cyclopentanol to cyclopentanone. The enzyme also shows considerable activity toward cyclohexanol [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=264, Percent_Identity=36.7424242424242, Blast_Score=130, Evalue=2e-30, Organism=Homo sapiens, GI15277342, Length=276, Percent_Identity=34.4202898550725, Blast_Score=128, Evalue=5e-30, Organism=Homo sapiens, GI66933014, Length=270, Percent_Identity=34.0740740740741, Blast_Score=109, Evalue=2e-24, Organism=Homo sapiens, GI31542939, Length=237, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI32483357, Length=268, Percent_Identity=32.4626865671642, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI59889578, Length=240, Percent_Identity=30.4166666666667, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI224922801, Length=178, Percent_Identity=36.5168539325843, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI4758504, Length=220, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI19923817, Length=271, Percent_Identity=31.3653136531365, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI7705925, Length=273, Percent_Identity=28.2051282051282, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI142976729, Length=210, Percent_Identity=29.0476190476191, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI40807363, Length=198, Percent_Identity=32.8282828282828, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI210032110, Length=209, Percent_Identity=27.7511961722488, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI109715829, Length=259, Percent_Identity=26.2548262548263, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI126723750, Length=271, Percent_Identity=27.6752767527675, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI83715985, Length=192, Percent_Identity=31.7708333333333, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI4503817, Length=202, Percent_Identity=31.1881188118812, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI4504505, Length=213, Percent_Identity=32.3943661971831, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI10190704, Length=271, Percent_Identity=29.520295202952, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI20149619, Length=205, Percent_Identity=29.7560975609756, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI32455239, Length=213, Percent_Identity=30.9859154929577, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI5031765, Length=213, Percent_Identity=30.9859154929577, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI5031737, Length=262, Percent_Identity=27.0992366412214, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI50726952, Length=204, Percent_Identity=30.3921568627451, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI310128830, Length=265, Percent_Identity=25.2830188679245, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI310115468, Length=265, Percent_Identity=25.2830188679245, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=30.1075268817204, Blast_Score=65, Evalue=9e-11, Organism=Homo sapiens, GI25282469, Length=216, Percent_Identity=26.8518518518519, Blast_Score=65, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=268, Percent_Identity=35.8208955223881, Blast_Score=132, Evalue=3e-32, Organism=Escherichia coli, GI1788459, Length=271, Percent_Identity=35.4243542435424, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI87082100, Length=275, Percent_Identity=35.2727272727273, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI87082160, Length=272, Percent_Identity=32.7205882352941, Blast_Score=115, Evalue=4e-27, Organism=Escherichia coli, GI2367175, Length=260, Percent_Identity=35.7692307692308, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1790717, Length=270, Percent_Identity=29.6296296296296, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1789378, Length=268, Percent_Identity=31.7164179104478, Blast_Score=106, Evalue=2e-24, Organism=Escherichia coli, GI1787905, Length=266, Percent_Identity=32.7067669172932, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1789208, Length=276, Percent_Identity=32.9710144927536, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1789057, Length=271, Percent_Identity=30.9963099630996, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1786812, Length=273, Percent_Identity=34.0659340659341, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI2367365, Length=272, Percent_Identity=28.6764705882353, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=184, Percent_Identity=27.7173913043478, Blast_Score=64, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17555706, Length=267, Percent_Identity=38.5767790262172, Blast_Score=134, Evalue=6e-32, Organism=Caenorhabditis elegans, GI25147288, Length=270, Percent_Identity=36.6666666666667, Blast_Score=132, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=36.4620938628159, Blast_Score=128, Evalue=3e-30, Organism=Caenorhabditis elegans, GI71994604, Length=269, Percent_Identity=36.0594795539033, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI71994600, Length=269, Percent_Identity=34.9442379182156, Blast_Score=123, Evalue=1e-28, Organism=Caenorhabditis elegans, GI17538480, Length=272, Percent_Identity=34.5588235294118, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=35.7400722021661, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17562990, Length=283, Percent_Identity=33.2155477031802, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17559104, Length=279, Percent_Identity=34.0501792114695, Blast_Score=117, Evalue=8e-27, Organism=Caenorhabditis elegans, GI17560220, Length=286, Percent_Identity=33.2167832167832, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI17562910, Length=284, Percent_Identity=32.7464788732394, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI17562908, Length=285, Percent_Identity=32.6315789473684, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17560332, Length=277, Percent_Identity=33.2129963898917, Blast_Score=110, Evalue=6e-25, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=32.8413284132841, Blast_Score=110, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=279, Percent_Identity=32.6164874551971, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562904, Length=277, Percent_Identity=31.0469314079422, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI72000259, Length=275, Percent_Identity=32, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17563726, Length=275, Percent_Identity=31.2727272727273, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=35.5, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI193204405, Length=284, Percent_Identity=32.3943661971831, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI17538486, Length=277, Percent_Identity=32.4909747292419, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17561402, Length=275, Percent_Identity=31.6363636363636, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=32.6007326007326, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538182, Length=284, Percent_Identity=32.0422535211268, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI115534694, Length=264, Percent_Identity=31.8181818181818, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17560676, Length=274, Percent_Identity=31.3868613138686, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=32.2751322751323, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203117, Length=192, Percent_Identity=31.7708333333333, Blast_Score=89, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17536025, Length=281, Percent_Identity=31.3167259786477, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=30.5699481865285, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17544670, Length=282, Percent_Identity=26.9503546099291, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=281, Percent_Identity=30.2491103202847, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17568967, Length=214, Percent_Identity=31.7757009345794, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17508651, Length=270, Percent_Identity=26.2962962962963, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=28.4210526315789, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17561272, Length=286, Percent_Identity=30.0699300699301, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=263, Percent_Identity=26.615969581749, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=273, Percent_Identity=26.3736263736264, Blast_Score=65, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=260, Percent_Identity=26.1538461538462, Blast_Score=63, Evalue=5e-11, Organism=Drosophila melanogaster, GI28571526, Length=269, Percent_Identity=38.2899628252788, Blast_Score=135, Evalue=2e-32, Organism=Drosophila melanogaster, GI23397609, Length=273, Percent_Identity=37.3626373626374, Blast_Score=134, Evalue=4e-32, Organism=Drosophila melanogaster, GI21357041, Length=276, Percent_Identity=35.8695652173913, Blast_Score=132, Evalue=3e-31, Organism=Drosophila melanogaster, GI24639444, Length=268, Percent_Identity=35.0746268656716, Blast_Score=131, Evalue=6e-31, Organism=Drosophila melanogaster, GI24644339, Length=269, Percent_Identity=35.3159851301115, Blast_Score=121, Evalue=6e-28, Organism=Drosophila melanogaster, GI21355319, Length=275, Percent_Identity=33.0909090909091, Blast_Score=114, Evalue=5e-26, Organism=Drosophila melanogaster, GI24644337, Length=270, Percent_Identity=32.962962962963, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI24640492, Length=209, Percent_Identity=29.6650717703349, Blast_Score=95, Evalue=6e-20, Organism=Drosophila melanogaster, GI17737361, Length=204, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24643142, Length=272, Percent_Identity=30.5147058823529, Blast_Score=83, Evalue=1e-16, Organism=Drosophila melanogaster, GI281364892, Length=192, Percent_Identity=32.2916666666667, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24649181, Length=259, Percent_Identity=28.1853281853282, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI18859837, Length=233, Percent_Identity=32.618025751073, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24641232, Length=211, Percent_Identity=30.3317535545024, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI21356301, Length=232, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI28571387, Length=205, Percent_Identity=28.2926829268293, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=30, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584752, Length=189, Percent_Identity=30.6878306878307, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.163 [H]
Molecular weight: Translated: 27675; Mature: 27544
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 4.4 %Met (Translated Protein) 5.1 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 4.1 %Met (Mature Protein) 4.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MASVKGKVSIVTGGASGIGRSAALVLAREGAAVMVTDIDEAGAQSVAAEINKAGGKAAAM CCCCCCEEEEEECCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCHHHH KQDVTDEAVWDGVFADTKSLLGMPSILVNNAGIAIGGAIMDYSLADWRKQMEVNTDSVFL HHCCCHHHHHCCHHHHHHHHHCCCHHEECCCCEEECHHHHHCHHHHHHHHHCCCCCEEEE GTRAAMRTMKGTGGSIVNISSVAGLRGASGASAYCASKGAVRLFTKAAAMECAQLGLNIR EHHHHHHHHCCCCCCEEEEHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEE VNSVHPGIIDTPIWQKSLTRMTETMQKEQSAVITAAFGGNGLDPKVIAAGSAPMGRPGAP EECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCCCCCCCH DEVAELILFLASDASSYITGQEHVVDGGLTAR HHHHHHHHHHHCCCCHHCCCCCEEECCCCCCC >Mature Secondary Structure ASVKGKVSIVTGGASGIGRSAALVLAREGAAVMVTDIDEAGAQSVAAEINKAGGKAAAM CCCCCEEEEEECCCCCCCCCEEEEEEECCCEEEEEECCHHHHHHHHHHHHHCCCCHHHH KQDVTDEAVWDGVFADTKSLLGMPSILVNNAGIAIGGAIMDYSLADWRKQMEVNTDSVFL HHCCCHHHHHCCHHHHHHHHHCCCHHEECCCCEEECHHHHHCHHHHHHHHHCCCCCEEEE GTRAAMRTMKGTGGSIVNISSVAGLRGASGASAYCASKGAVRLFTKAAAMECAQLGLNIR EHHHHHHHHCCCCCCEEEEHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEE VNSVHPGIIDTPIWQKSLTRMTETMQKEQSAVITAAFGGNGLDPKVIAAGSAPMGRPGAP EECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCCCCCCCH DEVAELILFLASDASSYITGQEHVVDGGLTAR HHHHHHHHHHHCCCCHHCCCCCEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12406764 [H]