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The map label for this gene is btuE [C]

Identifier: 114797596

GI number: 114797596

Start: 3239431

End: 3240036

Strand: Direct

Name: btuE [C]

Synonym: HNE_3064

Alternate gene names: 114797596

Gene position: 3239431-3240036 (Clockwise)

Preceding gene: 114800006

Following gene: 114798386

Centisome position: 87.43

GC content: 64.85

Gene sequence:

>606_bases
ATGCGCCTTGCGATCCTTGCCCTTGCCGCCCCCTTTCTGGCGGCCGCCTGCGCTGAGGCAACGGCCGGCCAGCCCACGGC
CAACGCCCCTGCTGCTCCAACAGAATTCCAGGCCGAGGAGCCCGCGCCCGCCATGTCCGCCACCCAGTTCACCAGCATCA
CCGGCCAGCCGCTCGACCTCACCGCCCTCGGCGCGAAGGCCATCCTGGTGGTAAACACCGCCTCGCGGTGCGGGTACACG
CCCCAATATGCCGGCCTCCAGAAACTCTACGAAGCCAACAAGGCGGACGGCCTGGTGATCGTCGGCGTCCCGTCCAATGA
TTTTGGCGGACAGGAGCCAGGCACCGAAGAGGACGTCAAATCCTTCTGCGAGATCAATTACGGCGTCACCTTCCCGCTGA
CGAAGAAGTACGCCGTCACAGGCGCGTCGCAGCACCCCTTCTATACCGGCGCCATCAAGACGCTGGGCGATCCCGCCCTG
CCGAAATGGAACTTCCACAAAATCCTCGTCAGCGCAGATGGCACGCCGCTCAAGGCCTATGCGTCTTCGGTAAAGCCCGA
TGACTCCGGCCTCGCCGCCGACATCGAAGCAGCGCTCGGCATCTGA

Upstream 100 bases:

>100_bases
GGCACCCGCGCCAACCTCACAAGCATTTCATATTTGTCAGGGATGACGCGCCCCCGCTGCGCTTATAGTCTGTTGTGGAA
ATGCCACAGGAGACGCGCTG

Downstream 100 bases:

>100_bases
TAAGGTCAGGCTTGCCCGCCGCCCGGCCTTGACGAAGCGGCATGTCCGGCGCCTATTCTCCCGCGCTGCACAAGAACGCA
AAGTCAGGAAGGAAATAGCC

Product: glutathione peroxidase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRLAILALAAPFLAAACAEATAGQPTANAPAAPTEFQAEEPAPAMSATQFTSITGQPLDLTALGAKAILVVNTASRCGYT
PQYAGLQKLYEANKADGLVIVGVPSNDFGGQEPGTEEDVKSFCEINYGVTFPLTKKYAVTGASQHPFYTGAIKTLGDPAL
PKWNFHKILVSADGTPLKAYASSVKPDDSGLAADIEAALGI

Sequences:

>Translated_201_residues
MRLAILALAAPFLAAACAEATAGQPTANAPAAPTEFQAEEPAPAMSATQFTSITGQPLDLTALGAKAILVVNTASRCGYT
PQYAGLQKLYEANKADGLVIVGVPSNDFGGQEPGTEEDVKSFCEINYGVTFPLTKKYAVTGASQHPFYTGAIKTLGDPAL
PKWNFHKILVSADGTPLKAYASSVKPDDSGLAADIEAALGI
>Mature_201_residues
MRLAILALAAPFLAAACAEATAGQPTANAPAAPTEFQAEEPAPAMSATQFTSITGQPLDLTALGAKAILVVNTASRCGYT
PQYAGLQKLYEANKADGLVIVGVPSNDFGGQEPGTEEDVKSFCEINYGVTFPLTKKYAVTGASQHPFYTGAIKTLGDPAL
PKWNFHKILVSADGTPLKAYASSVKPDDSGLAADIEAALGI

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=139, Percent_Identity=35.9712230215827, Blast_Score=90, Evalue=1e-18,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=31.25, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI75709200, Length=185, Percent_Identity=31.3513513513514, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI90903240, Length=150, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI41406084, Length=172, Percent_Identity=30.8139534883721, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI4557629, Length=150, Percent_Identity=34, Blast_Score=68, Evalue=5e-12,
Organism=Escherichia coli, GI1788003, Length=178, Percent_Identity=31.4606741573034, Blast_Score=108, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17506887, Length=150, Percent_Identity=34, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535473, Length=148, Percent_Identity=35.1351351351351, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71993584, Length=144, Percent_Identity=31.25, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=149, Percent_Identity=44.2953020134228, Blast_Score=133, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6319721, Length=150, Percent_Identity=41.3333333333333, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6322826, Length=150, Percent_Identity=36.6666666666667, Blast_Score=112, Evalue=5e-26,
Organism=Drosophila melanogaster, GI85726443, Length=153, Percent_Identity=35.9477124183007, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24656772, Length=168, Percent_Identity=35.1190476190476, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24656777, Length=168, Percent_Identity=35.1190476190476, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24656767, Length=172, Percent_Identity=36.6279069767442, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 20747; Mature: 20747

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAILALAAPFLAAACAEATAGQPTANAPAAPTEFQAEEPAPAMSATQFTSITGQPLDL
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCEE
TALGAKAILVVNTASRCGYTPQYAGLQKLYEANKADGLVIVGVPSNDFGGQEPGTEEDVK
EECCCEEEEEEECHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHH
SFCEINYGVTFPLTKKYAVTGASQHPFYTGAIKTLGDPALPKWNFHKILVSADGTPLKAY
HHHHCCCCEECCCCCEEEECCCCCCCEEECHHHHCCCCCCCCCCCEEEEEECCCCCHHHH
ASSVKPDDSGLAADIEAALGI
HHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MRLAILALAAPFLAAACAEATAGQPTANAPAAPTEFQAEEPAPAMSATQFTSITGQPLDL
CEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCEE
TALGAKAILVVNTASRCGYTPQYAGLQKLYEANKADGLVIVGVPSNDFGGQEPGTEEDVK
EECCCEEEEEEECHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHH
SFCEINYGVTFPLTKKYAVTGASQHPFYTGAIKTLGDPALPKWNFHKILVSADGTPLKAY
HHHHCCCCEECCCCCEEEECCCCCCCEEECHHHHCCCCCCCCCCCEEEEEECCCCCHHHH
ASSVKPDDSGLAADIEAALGI
HHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]