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The map label for this gene is acdA [H]

Identifier: 114797450

GI number: 114797450

Start: 1144302

End: 1145477

Strand: Reverse

Name: acdA [H]

Synonym: HNE_1134

Alternate gene names: 114797450

Gene position: 1145477-1144302 (Counterclockwise)

Preceding gene: 114799440

Following gene: 114798178

Centisome position: 30.92

GC content: 63.52

Gene sequence:

>1176_bases
ATGAGACTAGATCTGTCATCGCAGGATATTGAATTTCAGCAAGAAGTGCGAGCCTTCCTTCGGGACAAGCTGAGCCCGGA
ACTCGCCGCTGCCGGGCGGCTGGCCACCAGCGTGTTCATCGAGCCGGAATTCACCCTGCCCTGGCAGCGCATTCTGCATG
AGCGCGGCTGGGTCGCCCCGCATTGGCCGAAGGAATATGGTGGCACGGGCTGGACCGAGATGCAGCGATATATCTTTGCC
AGCGAGTGCGCCCGCGCGGGCGCGCCGGGGCTGGCGCCTATGGGGCTGGGTATGGTTGGGCCCTGCATCATTGGGTACGG
CACGCCCGAGCAGAAAGCCCATTACCTGCCGCGTATTCTCTCCGGGGAGGACTATTGGTGCCAGGGCTATTCAGAGCCGG
GATCGGGGTCGGACCTGGCGTCTTTGCAGCTTCGGGCGGTGAGTGATGGGGACGATTATGTGCTGAACGGCACGAAGATC
TGGACCACCCATGCCCACCACGCCAACAAGATGTTCTGCCTGGTGCGGACCGACCCCGAGGCCAAGGCGCAGAAGGGGAT
AACCTTCCTCCTGCTCGACATGTCTATCCCCGGTATCAAGGTGGACCCGATCATTACCCTCGCGGGCGAGCATGAGCTGA
ACCAGGTGTTCTTCGACGATGTGCGGGTGCCCAGGTCTGGCCGGCTCGGCGAGGAGAATGATGGCTGGTCGGTGGCAAAA
TACCTTTTGGAATTCGAGCGTTCCGGCGGATCGTCCGCCGGGCTGGAGGCCGGGCTCGGCCGGCTGCAGCGCTATGTGAC
GGGGCTTGGATGCCCTGACCTGATGCGGCTGGCGGCAGATCTTGGCACCCGCGTGGAGGCCATCAAGGGCACGGAGCAAC
GCATTCTCTCGGCGGTTTCCAGCGGAAAGCCGCCGGGGCCGGCCGCGTCGATGCTGAAGATCCAGCGGACGGAGCTGATG
CAGGCGGTGGATGAACTCGGCGTGCTGGCGAGCGGGATGTATGGCGGCGTTCAGCAGCTGGAAGCGGTGCATCCGCTGGG
CAATGTGGCGCCCATTGGACCGGCGGAGCTGGTGACGGCGATGCCCCGCTATCTCAACAACCGGGCGGGGTCGATCTATG
GCGGATCGAATGAGGTTCAGCGGAACATCATTGCGAAGGGGGTTTTGGGGCTCTGA

Upstream 100 bases:

>100_bases
CATTTTTGGCGAGCCCTATCAATTCCGTCAGCTTGCCCCATGCTGTCTTGCTTGCTCTGTCATGAGGGAAGCCAGAGATA
ATAAGCCGGGAGGCGCGACC

Downstream 100 bases:

>100_bases
AACTCAGAGAAACCTCAATACCCTGATTTTTCTGGACAAAACTGGACAGTTTGGCGCCAAAACGGGCGCAGGCGCGGACA
ATTGCCGGACAAACCCGGGC

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MRLDLSSQDIEFQQEVRAFLRDKLSPELAAAGRLATSVFIEPEFTLPWQRILHERGWVAPHWPKEYGGTGWTEMQRYIFA
SECARAGAPGLAPMGLGMVGPCIIGYGTPEQKAHYLPRILSGEDYWCQGYSEPGSGSDLASLQLRAVSDGDDYVLNGTKI
WTTHAHHANKMFCLVRTDPEAKAQKGITFLLLDMSIPGIKVDPIITLAGEHELNQVFFDDVRVPRSGRLGEENDGWSVAK
YLLEFERSGGSSAGLEAGLGRLQRYVTGLGCPDLMRLAADLGTRVEAIKGTEQRILSAVSSGKPPGPAASMLKIQRTELM
QAVDELGVLASGMYGGVQQLEAVHPLGNVAPIGPAELVTAMPRYLNNRAGSIYGGSNEVQRNIIAKGVLGL

Sequences:

>Translated_391_residues
MRLDLSSQDIEFQQEVRAFLRDKLSPELAAAGRLATSVFIEPEFTLPWQRILHERGWVAPHWPKEYGGTGWTEMQRYIFA
SECARAGAPGLAPMGLGMVGPCIIGYGTPEQKAHYLPRILSGEDYWCQGYSEPGSGSDLASLQLRAVSDGDDYVLNGTKI
WTTHAHHANKMFCLVRTDPEAKAQKGITFLLLDMSIPGIKVDPIITLAGEHELNQVFFDDVRVPRSGRLGEENDGWSVAK
YLLEFERSGGSSAGLEAGLGRLQRYVTGLGCPDLMRLAADLGTRVEAIKGTEQRILSAVSSGKPPGPAASMLKIQRTELM
QAVDELGVLASGMYGGVQQLEAVHPLGNVAPIGPAELVTAMPRYLNNRAGSIYGGSNEVQRNIIAKGVLGL
>Mature_391_residues
MRLDLSSQDIEFQQEVRAFLRDKLSPELAAAGRLATSVFIEPEFTLPWQRILHERGWVAPHWPKEYGGTGWTEMQRYIFA
SECARAGAPGLAPMGLGMVGPCIIGYGTPEQKAHYLPRILSGEDYWCQGYSEPGSGSDLASLQLRAVSDGDDYVLNGTKI
WTTHAHHANKMFCLVRTDPEAKAQKGITFLLLDMSIPGIKVDPIITLAGEHELNQVFFDDVRVPRSGRLGEENDGWSVAK
YLLEFERSGGSSAGLEAGLGRLQRYVTGLGCPDLMRLAADLGTRVEAIKGTEQRILSAVSSGKPPGPAASMLKIQRTELM
QAVDELGVLASGMYGGVQQLEAVHPLGNVAPIGPAELVTAMPRYLNNRAGSIYGGSNEVQRNIIAKGVLGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=394, Percent_Identity=29.1878172588832, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI187960098, Length=410, Percent_Identity=26.8292682926829, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI4557231, Length=410, Percent_Identity=26.8292682926829, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI226958412, Length=401, Percent_Identity=26.6832917705736, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI4501859, Length=402, Percent_Identity=25.1243781094527, Blast_Score=102, Evalue=8e-22,
Organism=Homo sapiens, GI226958414, Length=343, Percent_Identity=27.4052478134111, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4501857, Length=408, Percent_Identity=24.2647058823529, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI21361497, Length=247, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI76496475, Length=222, Percent_Identity=34.2342342342342, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4557235, Length=222, Percent_Identity=34.2342342342342, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7656849, Length=403, Percent_Identity=23.0769230769231, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI4503943, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI7669494, Length=180, Percent_Identity=30, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI48976061, Length=170, Percent_Identity=28.8235294117647, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI211971008, Length=170, Percent_Identity=28.8235294117647, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI87081958, Length=236, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17506239, Length=398, Percent_Identity=29.1457286432161, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17570075, Length=418, Percent_Identity=25.3588516746411, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=256, Percent_Identity=32.03125, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=349, Percent_Identity=30.0859598853868, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=266, Percent_Identity=29.6992481203008, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=255, Percent_Identity=30.1960784313725, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32563615, Length=194, Percent_Identity=37.1134020618557, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=254, Percent_Identity=26.7716535433071, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71985184, Length=365, Percent_Identity=25.2054794520548, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17505929, Length=212, Percent_Identity=26.8867924528302, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=263, Percent_Identity=26.2357414448669, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=207, Percent_Identity=29.4685990338164, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=224, Percent_Identity=23.2142857142857, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646207, Length=394, Percent_Identity=28.9340101522843, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI21356377, Length=396, Percent_Identity=27.020202020202, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363737, Length=213, Percent_Identity=35.2112676056338, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21355753, Length=207, Percent_Identity=34.7826086956522, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24660351, Length=250, Percent_Identity=30.4, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=25.4691689008043, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 42404; Mature: 42404

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDLSSQDIEFQQEVRAFLRDKLSPELAAAGRLATSVFIEPEFTLPWQRILHERGWVAP
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCCC
HWPKEYGGTGWTEMQRYIFASECARAGAPGLAPMGLGMVGPCIIGYGTPEQKAHYLPRIL
CCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCEEEECCCCHHHHHHHHHHH
SGEDYWCQGYSEPGSGSDLASLQLRAVSDGDDYVLNGTKIWTTHAHHANKMFCLVRTDPE
CCCCCEECCCCCCCCCCCEEEEEEEEECCCCCEEECCEEEEEEECCCCCEEEEEEECCCH
AKAQKGITFLLLDMSIPGIKVDPIITLAGEHELNQVFFDDVRVPRSGRLGEENDGWSVAK
HHHHCCCEEEEEECCCCCEEECCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
YLLEFERSGGSSAGLEAGLGRLQRYVTGLGCPDLMRLAADLGTRVEAIKGTEQRILSAVS
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHH
SGKPPGPAASMLKIQRTELMQAVDELGVLASGMYGGVQQLEAVHPLGNVAPIGPAELVTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
MPRYLNNRAGSIYGGSNEVQRNIIAKGVLGL
HHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLDLSSQDIEFQQEVRAFLRDKLSPELAAAGRLATSVFIEPEFTLPWQRILHERGWVAP
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEEECCCCCCCHHHHHHHCCCCCC
HWPKEYGGTGWTEMQRYIFASECARAGAPGLAPMGLGMVGPCIIGYGTPEQKAHYLPRIL
CCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCEEEECCCCHHHHHHHHHHH
SGEDYWCQGYSEPGSGSDLASLQLRAVSDGDDYVLNGTKIWTTHAHHANKMFCLVRTDPE
CCCCCEECCCCCCCCCCCEEEEEEEEECCCCCEEECCEEEEEEECCCCCEEEEEEECCCH
AKAQKGITFLLLDMSIPGIKVDPIITLAGEHELNQVFFDDVRVPRSGRLGEENDGWSVAK
HHHHCCCEEEEEECCCCCEEECCEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
YLLEFERSGGSSAGLEAGLGRLQRYVTGLGCPDLMRLAADLGTRVEAIKGTEQRILSAVS
HHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHCCHHHHHHHHHH
SGKPPGPAASMLKIQRTELMQAVDELGVLASGMYGGVQQLEAVHPLGNVAPIGPAELVTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
MPRYLNNRAGSIYGGSNEVQRNIIAKGVLGL
HHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]