| Definition | Hyphomonas neptunium ATCC 15444 chromosome, complete genome. |
|---|---|
| Accession | NC_008358 |
| Length | 3,705,021 |
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The map label for this gene is murC [H]
Identifier: 114799440
GI number: 114799440
Start: 1146377
End: 1147786
Strand: Reverse
Name: murC [H]
Synonym: HNE_1136
Alternate gene names: 114799440
Gene position: 1147786-1146377 (Counterclockwise)
Preceding gene: 114797248
Following gene: 114797450
Centisome position: 30.98
GC content: 67.3
Gene sequence:
>1410_bases ATGACTCACCCCACGCGCTACTTCTTTTGCGGCATCGGCGGCTCCGGCATGTTGCCGCTGGCGTTGATCCTGCTCGATCA GGGCCACATCATCGAAGGCTCGGACCGGTCGCTCGATCAGGGGCGCACGCAAGCAAAGTTTGACTATCTGCGCAGCAAGG GCATCCGCCTTTTCCCGCAGGATGGCAGCGGCGTGACGAGCGCCGAGCAGGTCGTCGTGGCATCGGCCGCCGTGGAAGAC ACTGTGCCCGATATTGCCGCCGCCCTGCGCGTCGGCGCGCGGCGGATGAGCCGGGCGCAGATGCTGTCTGCCCTCTTCAA CGCCGCGCCCACAGCCATCGGCGTGGCGGGTACGAGCGGCAAGTCCACCACCACCGGTATGATCGCCTGGATACTCCACC ACGCCGGCAAAAGCCCGACCGTGATGAACGGCGCCGTGATGAAGAACTTCCAGACACCGGACGCCCTCTTCGCCAGCTCG CTGGTGGGCGCCAGCGGCATCTTCGTCTCCGAAGTGGACGAAAGCGACGGCTCGATTGCCGGGTACAACCCGCGCGTTGC GGTCGTCTCGAACATCTCGCTCGACCATAAATCCATGGACGAGTTGCGCGCCCTCTTCGGCGGCTTTGCGGCCCGCGCCG AAACCGTCGTGCTGAACCTCGACAATGACGAGACCGCGCGGATGGCCGGGGACTTTCCGGGGGCGGTCACCTACAGCCTC GAGAACCCCGCCGCCCGCCTCACGGCGCAGAACATCGCGCCCGCGCCCACCCACATCACTTTCTCCGTACACGACCAGAC ATCCGGCGCCACCGCCCCCATTCGCCTCGCCACGCCGGGGCGCCACAACGTCTCAAACGTGCTGGCCGCTATTGCCGCCA CGCTCGCCTGCGGCGTCACGCTGGCAGAGGCTGCCAAGGCTCTCGCCAGCTTCGCGGGCATCTCCCGCCGCTTCGATGTA ATCGGCACGGAAGGCGGCGTGACGGTCATCGACGATTTCGGGCACAACCCGGACAAGATCGCCGCCACCCTGCGCACCGT GAACCAGTTCCCCGGCCGCGTGCTGGTGATGTTCCAGCCCCACGGCTTTGGCCCCTTGCGCAACATGCGGCGCGAGTTTG CGGCCTGTTTTGCCGAGAATCTGGACGCCGAAGACATCCTCCTGATGCCCGAGCCGGCTTACTTCGGCGGCACAGTAGAC CGCTCGGTCGGCAGCCAGGACCTTGCCGCAGACATCCGCGCCCTTGGCCGCGAGGCCCACGCGCTGGGCGACCGGGCCGC CTGCGGCGCGCGCCTGTTCGAACTGGCAAAGCCGGGCGACCGCATCCTCGTCATGGGCGCCCGCGATGATACCCTCACCG TCTTCGCGCAGGAATTGCTCGCCACCTTCAAGGCGCGCGCGGGCGCCTGA
Upstream 100 bases:
>100_bases CCCGCTCGAGATGTGAGTTTCAAATAGTTATGCGCGATACGAAAAGTAACATAATTCACTGATGTGTAGCTCTACATCCC CCTGTTATAAGCTCCCAACC
Downstream 100 bases:
>100_bases AAAACTCCAACGGCGTTGGAGTTTTTTTGGAGGCTTTTCAGGCCCCGCCGCCCTGCCCGATATAGCCCAGCGTGGTGGCC AGACGGATCGTCTGAGAGCG
Product: putative UDP-N-acetylmuramate--L-alanine ligase
Products: NA
Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]
Number of amino acids: Translated: 469; Mature: 468
Protein sequence:
>469_residues MTHPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQDGSGVTSAEQVVVASAAVED TVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSGKSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASS LVGASGIFVSEVDESDGSIAGYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVTLAEAAKALASFAGISRRFDV IGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQPHGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVD RSVGSQDLAADIRALGREAHALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA
Sequences:
>Translated_469_residues MTHPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQDGSGVTSAEQVVVASAAVED TVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSGKSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASS LVGASGIFVSEVDESDGSIAGYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVTLAEAAKALASFAGISRRFDV IGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQPHGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVD RSVGSQDLAADIRALGREAHALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA >Mature_468_residues THPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQDGSGVTSAEQVVVASAAVEDT VPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSGKSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASSL VGASGIFVSEVDESDGSIAGYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSLE NPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVTLAEAAKALASFAGISRRFDVI GTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQPHGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVDR SVGSQDLAADIRALGREAHALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA
Specific function: Cell wall formation [H]
COG id: COG0773
COG function: function code M; UDP-N-acetylmuramate-alanine ligase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the MurCDEF family [H]
Homologues:
Organism=Escherichia coli, GI1790680, Length=460, Percent_Identity=28.2608695652174, Blast_Score=139, Evalue=4e-34, Organism=Escherichia coli, GI1786279, Length=392, Percent_Identity=31.8877551020408, Blast_Score=120, Evalue=1e-28,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004101 - InterPro: IPR013221 - InterPro: IPR000713 - InterPro: IPR016040 - InterPro: IPR005758 [H]
Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]
EC number: =6.3.2.8 [H]
Molecular weight: Translated: 49239; Mature: 49108
Theoretical pI: Translated: 6.44; Mature: 6.44
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTHPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQ CCCCCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCEEEEC DGSGVTSAEQVVVASAAVEDTVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSG CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC KSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASSLVGASGIFVSEVDESDGSIA CCCHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEE GYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCCEEEEEC ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVT CCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH LAEAAKALASFAGISRRFDVIGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQP HHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC HGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVDRSVGSQDLAADIRALGREAH CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH ALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA HCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure THPTRYFFCGIGGSGMLPLALILLDQGHIIEGSDRSLDQGRTQAKFDYLRSKGIRLFPQ CCCCEEEEEECCCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHCCCCEEEEC DGSGVTSAEQVVVASAAVEDTVPDIAAALRVGARRMSRAQMLSALFNAAPTAIGVAGTSG CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC KSTTTGMIAWILHHAGKSPTVMNGAVMKNFQTPDALFASSLVGASGIFVSEVDESDGSIA CCCHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCEE GYNPRVAVVSNISLDHKSMDELRALFGGFAARAETVVLNLDNDETARMAGDFPGAVTYSL CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCHHHHCCCCCCEEEEEC ENPAARLTAQNIAPAPTHITFSVHDQTSGATAPIRLATPGRHNVSNVLAAIAATLACGVT CCCHHHHHHCCCCCCCCEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH LAEAAKALASFAGISRRFDVIGTEGGVTVIDDFGHNPDKIAATLRTVNQFPGRVLVMFQP HHHHHHHHHHHHCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC HGFGPLRNMRREFAACFAENLDAEDILLMPEPAYFGGTVDRSVGSQDLAADIRALGREAH CCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH ALGDRAACGARLFELAKPGDRILVMGARDDTLTVFAQELLATFKARAGA HCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA