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The map label for this gene is zur [H]

Identifier: 114797229

GI number: 114797229

Start: 658000

End: 658563

Strand: Reverse

Name: zur [H]

Synonym: HNE_0655

Alternate gene names: 114797229

Gene position: 658563-658000 (Counterclockwise)

Preceding gene: 114797971

Following gene: 114797914

Centisome position: 17.77

GC content: 60.99

Gene sequence:

>564_bases
GTGATTTGCAGACACCGTCCAGTGCCTCTTGCGGTGATCCCCCTTCACATTCGTCTCAAAACACCAGACATTAGGGGAAT
GGCCCATTCACACGCCCACGATCATGGTTCTGCCAACACGCCCTGCGCCCCGCAGGACGCGGACGCCTTCCTTGCAGAGG
CCGAAGCTCTGGTGGTTCGCAAGGGCCAGCGGATGACGCGCATCCGCCGCAAGGTGCTGCGCCTGCTGCTGGAAAATGAC
GGCCCGGCCAAAGCCTATGACCTTCTGGCCAATCTGGACGGGGAAGGCGCGGCCAAGCCGCCGACGATTTATCGCGCGCT
GGATTTCCTTCAGGAGACCGGCCTCGTCCACAAGATCGAAAGCCTCAACGCCTATGTGGCGTGCGGGCATACAAGCCACA
ATCATTCGGCGGTTTTCCTGATCTGCGAGATCTGCCAGAACGCCGAAGAACTTCATGCCGTGGCCACCAGCCAGGCGCTC
AGACAGGAAACAGAAGCCGCAGGCTTCCAGATGACCCGCGCCGTGATCGAAGTGCGCGGGCGCTGCAGGAGATGTAACGC
ATGA

Upstream 100 bases:

>100_bases
TGACCGATTTCCGCCAGAGCTCAAGCCCTTCCCGCTCCGACAATTGCATCCCGGCCAATCCTCCACGCTACGATTACTGC
GGCACAGCGCTGAATCTCAG

Downstream 100 bases:

>100_bases
TCCCACTCTGGCAGGGTAGCTGTAACCAGTGGGACTGCGATGAGATGGGGCACATGAATGTGCGCGTCTATGTCGAGAAA
CAGCTGGAAGGCATGATCGC

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MICRHRPVPLAVIPLHIRLKTPDIRGMAHSHAHDHGSANTPCAPQDADAFLAEAEALVVRKGQRMTRIRRKVLRLLLEND
GPAKAYDLLANLDGEGAAKPPTIYRALDFLQETGLVHKIESLNAYVACGHTSHNHSAVFLICEICQNAEELHAVATSQAL
RQETEAAGFQMTRAVIEVRGRCRRCNA

Sequences:

>Translated_187_residues
MICRHRPVPLAVIPLHIRLKTPDIRGMAHSHAHDHGSANTPCAPQDADAFLAEAEALVVRKGQRMTRIRRKVLRLLLEND
GPAKAYDLLANLDGEGAAKPPTIYRALDFLQETGLVHKIESLNAYVACGHTSHNHSAVFLICEICQNAEELHAVATSQAL
RQETEAAGFQMTRAVIEVRGRCRRCNA
>Mature_187_residues
MICRHRPVPLAVIPLHIRLKTPDIRGMAHSHAHDHGSANTPCAPQDADAFLAEAEALVVRKGQRMTRIRRKVLRLLLEND
GPAKAYDLLANLDGEGAAKPPTIYRALDFLQETGLVHKIESLNAYVACGHTSHNHSAVFLICEICQNAEELHAVATSQAL
RQETEAAGFQMTRAVIEVRGRCRRCNA

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=138, Percent_Identity=41.304347826087, Blast_Score=98, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 20610; Mature: 20610

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICRHRPVPLAVIPLHIRLKTPDIRGMAHSHAHDHGSANTPCAPQDADAFLAEAEALVVR
CCCCCCCCCEEEEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KGQRMTRIRRKVLRLLLENDGPAKAYDLLANLDGEGAAKPPTIYRALDFLQETGLVHKIE
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHH
SLNAYVACGHTSHNHSAVFLICEICQNAEELHAVATSQALRQETEAAGFQMTRAVIEVRG
HCCEEEEECCCCCCCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RCRRCNA
HHHCCCC
>Mature Secondary Structure
MICRHRPVPLAVIPLHIRLKTPDIRGMAHSHAHDHGSANTPCAPQDADAFLAEAEALVVR
CCCCCCCCCEEEEEEEEEEECCCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
KGQRMTRIRRKVLRLLLENDGPAKAYDLLANLDGEGAAKPPTIYRALDFLQETGLVHKIE
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCHHHHHH
SLNAYVACGHTSHNHSAVFLICEICQNAEELHAVATSQALRQETEAAGFQMTRAVIEVRG
HCCEEEEECCCCCCCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RCRRCNA
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]