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The map label for this gene is murA

Identifier: 114797160

GI number: 114797160

Start: 1378444

End: 1379724

Strand: Direct

Name: murA

Synonym: HNE_1344

Alternate gene names: 114797160

Gene position: 1378444-1379724 (Clockwise)

Preceding gene: 114798086

Following gene: 114797987

Centisome position: 37.2

GC content: 66.74

Gene sequence:

>1281_bases
ATGGATCGTCTTCACATCATTGGCGGCAGCCCTCTCAGCGGCCGCATTCCCGTCTCCGGCGCGAAAAACTCCGCGTTGAA
GCTCATGGTCGCCTGCCTCCTCACGGACCAGCCGATCGAATTCACCAATATGCCGAATCTGGCAGACACGCGCTTTCTGG
CGCAGCTGCTGGAGACGCTGGGGGTTGAGGTTTACTGGCCCAGGGGCTCGTCCACCTGTCACCTCAACGCGGCAGAGCTG
AAATCCACCATCGCGCCCTATGAACAGGTGCGGAAGATGCGGGCGAGCTTCAATGTGCTCGGGCCGCTGGTGGCGCGCTC
CGGCCATGCTACCGTCTCGCTGCCCGGCGGCTGCGCCATTGGCGCCCGCCCGGTGGATCTGCACCTTCAGGCGCTGGAAG
CCATGGGCGCAGATCTGCGCGTGGAGCAGGGCTATGTGAAGGCCGCCGCCATTCATGGCCTGAAAGGCGCGCATATCAAC
TTCTCGACGGTTTCGGTGGGCGCCACCGAGCACACGATGCTCGCCGCCACACTGGCCAAGGGCGAGACGATCCTGGAGAA
CGCTGCGCGCGAGCCCGAGATCGAAGACCTCGCCCACTGCCTCAACCAGATGGGCGCCCAGATCACCGGCGCGGGCACGC
CGATCATCCGCATCAAGGGCGTGGAGGCTCTCAAAGGCACCACCTATTCCGTGATGCCAGACCGGATCGAGGCGGGCACC
TTCGCCATGGCTGCCGCCGCTGCGGGCGGCGACGTGACGCTGGACGGCGCGCCTGTGGCGGCGCTGGGCGCAATGATCGC
CAAGCTGCGCGAAGCGGGCGTGACGGTGGACGCCGACGAAGCTGCCTCCACGATCCGCATCCGCCGCAATGGCACGCCGC
TCAAAGCCGTCAGCCTGTCGACCCAGCCCCATCCCGGCTTCCCGACAGACCTGCAAGCTCAGTTCATGGCGCTGATGACG
CTCGCCAGCGGCACCAGCATCATCCGCGAGACGATCTTCGAGAACCGCTTCATGCACGCGCCCGAGCTTGCCCGCCTTGG
CGCGGACATCACCGTGCGCGGCCAGGAAGCGGTGGTGAAGGGCGTTGCCCAGCTGACCGCCGCACCTGTGATGGCGACCG
ATCTGCGCGCCTCGGTGTCACTCGTCATCGCCGGCCTCGCCGCCCAGGGCGAAACGGTCGTCAACCGCATCTACCACCTC
GACCGGGGCTTCGAGCGCCTGGAAGAGAAGCTGGGGGCCTGCGGGGCACGGATCGAGCGGCGCTCGGGCGAAGAGGAATA
A

Upstream 100 bases:

>100_bases
GGGCGTGCGAGGGCTTGCCCGGTTGCCGTTGCAGTTAAAATCCTGAAACCACACACAATCTGGCCCTTACAAAGCCGCGA
AGCACGGTATATCTGCGGCC

Downstream 100 bases:

>100_bases
CTCAAAGCCCTTTCCACCCTAGGCGGGGTGAGGGGGCTTTGAAAGCCCGCATCTTTCCGTTGAGGTTCCGCGCCGAATAC
GGCTAGGAACGCAATTGACT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MDRLHIIGGSPLSGRIPVSGAKNSALKLMVACLLTDQPIEFTNMPNLADTRFLAQLLETLGVEVYWPRGSSTCHLNAAEL
KSTIAPYEQVRKMRASFNVLGPLVARSGHATVSLPGGCAIGARPVDLHLQALEAMGADLRVEQGYVKAAAIHGLKGAHIN
FSTVSVGATEHTMLAATLAKGETILENAAREPEIEDLAHCLNQMGAQITGAGTPIIRIKGVEALKGTTYSVMPDRIEAGT
FAMAAAAAGGDVTLDGAPVAALGAMIAKLREAGVTVDADEAASTIRIRRNGTPLKAVSLSTQPHPGFPTDLQAQFMALMT
LASGTSIIRETIFENRFMHAPELARLGADITVRGQEAVVKGVAQLTAAPVMATDLRASVSLVIAGLAAQGETVVNRIYHL
DRGFERLEEKLGACGARIERRSGEEE

Sequences:

>Translated_426_residues
MDRLHIIGGSPLSGRIPVSGAKNSALKLMVACLLTDQPIEFTNMPNLADTRFLAQLLETLGVEVYWPRGSSTCHLNAAEL
KSTIAPYEQVRKMRASFNVLGPLVARSGHATVSLPGGCAIGARPVDLHLQALEAMGADLRVEQGYVKAAAIHGLKGAHIN
FSTVSVGATEHTMLAATLAKGETILENAAREPEIEDLAHCLNQMGAQITGAGTPIIRIKGVEALKGTTYSVMPDRIEAGT
FAMAAAAAGGDVTLDGAPVAALGAMIAKLREAGVTVDADEAASTIRIRRNGTPLKAVSLSTQPHPGFPTDLQAQFMALMT
LASGTSIIRETIFENRFMHAPELARLGADITVRGQEAVVKGVAQLTAAPVMATDLRASVSLVIAGLAAQGETVVNRIYHL
DRGFERLEEKLGACGARIERRSGEEE
>Mature_426_residues
MDRLHIIGGSPLSGRIPVSGAKNSALKLMVACLLTDQPIEFTNMPNLADTRFLAQLLETLGVEVYWPRGSSTCHLNAAEL
KSTIAPYEQVRKMRASFNVLGPLVARSGHATVSLPGGCAIGARPVDLHLQALEAMGADLRVEQGYVKAAAIHGLKGAHIN
FSTVSVGATEHTMLAATLAKGETILENAAREPEIEDLAHCLNQMGAQITGAGTPIIRIKGVEALKGTTYSVMPDRIEAGT
FAMAAAAAGGDVTLDGAPVAALGAMIAKLREAGVTVDADEAASTIRIRRNGTPLKAVSLSTQPHPGFPTDLQAQFMALMT
LASGTSIIRETIFENRFMHAPELARLGADITVRGQEAVVKGVAQLTAAPVMATDLRASVSLVIAGLAAQGETVVNRIYHL
DRGFERLEEKLGACGARIERRSGEEE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=424, Percent_Identity=51.8867924528302, Blast_Score=417, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_HYPNA (Q0C2I2)

Other databases:

- EMBL:   CP000158
- RefSeq:   YP_760061.1
- ProteinModelPortal:   Q0C2I2
- SMR:   Q0C2I2
- STRING:   Q0C2I2
- GeneID:   4287619
- GenomeReviews:   CP000158_GR
- KEGG:   hne:HNE_1344
- NMPDR:   fig|228405.5.peg.1305
- TIGR:   HNE_1344
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   ICGDTDG
- PhylomeDB:   Q0C2I2
- ProtClustDB:   PRK09369
- BioCyc:   HNEP81032:HNE_1344-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44849; Mature: 44849

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLHIIGGSPLSGRIPVSGAKNSALKLMVACLLTDQPIEFTNMPNLADTRFLAQLLETL
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GVEVYWPRGSSTCHLNAAELKSTIAPYEQVRKMRASFNVLGPLVARSGHATVSLPGGCAI
CCEEEECCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GARPVDLHLQALEAMGADLRVEQGYVKAAAIHGLKGAHINFSTVSVGATEHTMLAATLAK
CCCCHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHC
GETILENAAREPEIEDLAHCLNQMGAQITGAGTPIIRIKGVEALKGTTYSVMPDRIEAGT
CHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCHHHCCCEEEECCCCCCCCH
FAMAAAAAGGDVTLDGAPVAALGAMIAKLREAGVTVDADEAASTIRIRRNGTPLKAVSLS
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCEEEEEEC
TQPHPGFPTDLQAQFMALMTLASGTSIIRETIFENRFMHAPELARLGADITVRGQEAVVK
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHCCCCEEECCHHHHHH
GVAQLTAAPVMATDLRASVSLVIAGLAAQGETVVNRIYHLDRGFERLEEKLGACGARIER
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGEEE
CCCCCC
>Mature Secondary Structure
MDRLHIIGGSPLSGRIPVSGAKNSALKLMVACLLTDQPIEFTNMPNLADTRFLAQLLETL
CCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GVEVYWPRGSSTCHLNAAELKSTIAPYEQVRKMRASFNVLGPLVARSGHATVSLPGGCAI
CCEEEECCCCCEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GARPVDLHLQALEAMGADLRVEQGYVKAAAIHGLKGAHINFSTVSVGATEHTMLAATLAK
CCCCHHHHHHHHHHCCCCEEEECCHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHC
GETILENAAREPEIEDLAHCLNQMGAQITGAGTPIIRIKGVEALKGTTYSVMPDRIEAGT
CHHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCHHHCCCEEEECCCCCCCCH
FAMAAAAAGGDVTLDGAPVAALGAMIAKLREAGVTVDADEAASTIRIRRNGTPLKAVSLS
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCEEEEEEC
TQPHPGFPTDLQAQFMALMTLASGTSIIRETIFENRFMHAPELARLGADITVRGQEAVVK
CCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHCCCCEEECCHHHHHH
GVAQLTAAPVMATDLRASVSLVIAGLAAQGETVVNRIYHLDRGFERLEEKLGACGARIER
HHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSGEEE
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA