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The map label for this gene is pksS [H]

Identifier: 114798086

GI number: 114798086

Start: 1377163

End: 1378389

Strand: Direct

Name: pksS [H]

Synonym: HNE_1343

Alternate gene names: 114798086

Gene position: 1377163-1378389 (Clockwise)

Preceding gene: 114799109

Following gene: 114797160

Centisome position: 37.17

GC content: 67.07

Gene sequence:

>1227_bases
ATGCCTGCCGCGCCCGCCCTGCAAAAACTGACAGTTGGGGGGCAAGCCTTCCTGCGCGATCCCCACGCCCGTCTGACCTG
CGCGCTGGAGGCCGGCCCGCTGGCGCAGACGCGCCTGCTGGTGTTTGGCAGGATCACCGCCGTGCTGAGCCATGCCGGCA
TCACCGAGATGATGAAGGATGCCGGGCGCTTTACGGTGGACGCCCGCAATGCGGGGCATTCTTCGGCGCTGGGCATGCCA
TTCCTGCCCAAATCCCTGAAATTACTGGCCGAAAACCTGCTCACCCTGGACGAGCCCCACCATACCCGCCTGCGGCGGCT
GGCGGACGCCCCGTTCCGGCGAGCGGCGATTGAGGGCATGCGCCCGGCGGTCGAGGCCCAATGCGCGCGGCTGCTGGATG
AGATGGCGCGGTCTGGGAACACCGATCTGGTCTCGGGCCTCTGCCGGCCCCTGCCGATCCAGGTGATCTGCGACCTGCTG
GGGCTGTCAGATGCGCGCCGCGAAGGGCTGGTACGGGTGTTTTCCGGCTTTTCGGGCGCGGGCACCCTGGAGGCCATCGG
CGTGTTAATGAAGACCGGCTGGGTGCAGAGCGAGCTGCGCCAGGAGTTTGCCGAGGTGCGCGCCGTCCCGCGCCCCGGCC
TGATTACAGAGCTGGTCCATGCCGAAGCCGAAGACGGCCGCCTGACGGAGGATGAACTCCTCTCGATGGTCTTCATCCTG
TTTGCGGCAGGCCATGAGACGACGACGCATTTCATCTCTTCCAGCGTCTGGACGATGCTGACGCAGCCCGGCGCGCGCGA
GGCCATCGCGGCGATGGATGGGGAGGCGCTGAACGTAGCGGTCGACGAGCTGATGCGCTTCAGCGGCCCGGTGCAGTTCA
CCAAGCCGCGCTATGCGCGTGAGGATACCGAGTTTCTGGGCCAGCCGATCAAGCGCGGGAAGCCTGTGATGGCGCTGCTC
GCGGCGGGCAATCTGGACCCGGCGGCGTTTGACGATCCCCTGACGCTGAACCTTGGCCGCCGGCCCAACCGTCATCTCAG
CTGGGGATGGGGCCCGCATCTCTGCCTCGGCATGCATCTGGCCAAGGCTGAATGCGAGATTGCGCTGCGCCAGATTCTGG
AGCGCTGGCCGGGCGTGGAGATCGACGGCGACCCTGCCGCGCTCAAATGGAGCCAGCGGCCGGGCGTGCGAGGGCTTGCC
CGGTTGCCGTTGCAGTTAAAATCCTGA

Upstream 100 bases:

>100_bases
CCGCCGGGCCGAAGCGCTGAGGGCGAATCTGCGCCGCCGCAAGGCCGCCGCCCGCAAGGATGCCGCGCCCCCGCCGGATG
GAAAATCAGGCTAGCGCCCC

Downstream 100 bases:

>100_bases
AACCACACACAATCTGGCCCTTACAAAGCCGCGAAGCACGGTATATCTGCGGCCATGGATCGTCTTCACATCATTGGCGG
CAGCCCTCTCAGCGGCCGCA

Product: cytochrome P450 family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MPAAPALQKLTVGGQAFLRDPHARLTCALEAGPLAQTRLLVFGRITAVLSHAGITEMMKDAGRFTVDARNAGHSSALGMP
FLPKSLKLLAENLLTLDEPHHTRLRRLADAPFRRAAIEGMRPAVEAQCARLLDEMARSGNTDLVSGLCRPLPIQVICDLL
GLSDARREGLVRVFSGFSGAGTLEAIGVLMKTGWVQSELRQEFAEVRAVPRPGLITELVHAEAEDGRLTEDELLSMVFIL
FAAGHETTTHFISSSVWTMLTQPGAREAIAAMDGEALNVAVDELMRFSGPVQFTKPRYAREDTEFLGQPIKRGKPVMALL
AAGNLDPAAFDDPLTLNLGRRPNRHLSWGWGPHLCLGMHLAKAECEIALRQILERWPGVEIDGDPAALKWSQRPGVRGLA
RLPLQLKS

Sequences:

>Translated_408_residues
MPAAPALQKLTVGGQAFLRDPHARLTCALEAGPLAQTRLLVFGRITAVLSHAGITEMMKDAGRFTVDARNAGHSSALGMP
FLPKSLKLLAENLLTLDEPHHTRLRRLADAPFRRAAIEGMRPAVEAQCARLLDEMARSGNTDLVSGLCRPLPIQVICDLL
GLSDARREGLVRVFSGFSGAGTLEAIGVLMKTGWVQSELRQEFAEVRAVPRPGLITELVHAEAEDGRLTEDELLSMVFIL
FAAGHETTTHFISSSVWTMLTQPGAREAIAAMDGEALNVAVDELMRFSGPVQFTKPRYAREDTEFLGQPIKRGKPVMALL
AAGNLDPAAFDDPLTLNLGRRPNRHLSWGWGPHLCLGMHLAKAECEIALRQILERWPGVEIDGDPAALKWSQRPGVRGLA
RLPLQLKS
>Mature_407_residues
PAAPALQKLTVGGQAFLRDPHARLTCALEAGPLAQTRLLVFGRITAVLSHAGITEMMKDAGRFTVDARNAGHSSALGMPF
LPKSLKLLAENLLTLDEPHHTRLRRLADAPFRRAAIEGMRPAVEAQCARLLDEMARSGNTDLVSGLCRPLPIQVICDLLG
LSDARREGLVRVFSGFSGAGTLEAIGVLMKTGWVQSELRQEFAEVRAVPRPGLITELVHAEAEDGRLTEDELLSMVFILF
AAGHETTTHFISSSVWTMLTQPGAREAIAAMDGEALNVAVDELMRFSGPVQFTKPRYAREDTEFLGQPIKRGKPVMALLA
AGNLDPAAFDDPLTLNLGRRPNRHLSWGWGPHLCLGMHLAKAECEIALRQILERWPGVEIDGDPAALKWSQRPGVRGLAR
LPLQLKS

Specific function: Involved in the metabolism of the antibiotic polyketide bacillaene which is involved in secondary metabolism. The substrate is dihydrobacillaene [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44448; Mature: 44317

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAPALQKLTVGGQAFLRDPHARLTCALEAGPLAQTRLLVFGRITAVLSHAGITEMMKD
CCCCCCHHHHHCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
AGRFTVDARNAGHSSALGMPFLPKSLKLLAENLLTLDEPHHTRLRRLADAPFRRAAIEGM
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCC
RPAVEAQCARLLDEMARSGNTDLVSGLCRPLPIQVICDLLGLSDARREGLVRVFSGFSGA
CHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
GTLEAIGVLMKTGWVQSELRQEFAEVRAVPRPGLITELVHAEAEDGRLTEDELLSMVFIL
CHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
FAAGHETTTHFISSSVWTMLTQPGAREAIAAMDGEALNVAVDELMRFSGPVQFTKPRYAR
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EDTEFLGQPIKRGKPVMALLAAGNLDPAAFDDPLTLNLGRRPNRHLSWGWGPHLCLGMHL
CCHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
AKAECEIALRQILERWPGVEIDGDPAALKWSQRPGVRGLARLPLQLKS
HHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
PAAPALQKLTVGGQAFLRDPHARLTCALEAGPLAQTRLLVFGRITAVLSHAGITEMMKD
CCCCCHHHHHCCCHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
AGRFTVDARNAGHSSALGMPFLPKSLKLLAENLLTLDEPHHTRLRRLADAPFRRAAIEGM
CCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHCC
RPAVEAQCARLLDEMARSGNTDLVSGLCRPLPIQVICDLLGLSDARREGLVRVFSGFSGA
CHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCC
GTLEAIGVLMKTGWVQSELRQEFAEVRAVPRPGLITELVHAEAEDGRLTEDELLSMVFIL
CHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHH
FAAGHETTTHFISSSVWTMLTQPGAREAIAAMDGEALNVAVDELMRFSGPVQFTKPRYAR
HHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
EDTEFLGQPIKRGKPVMALLAAGNLDPAAFDDPLTLNLGRRPNRHLSWGWGPHLCLGMHL
CCHHHHCCHHHCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHH
AKAECEIALRQILERWPGVEIDGDPAALKWSQRPGVRGLARLPLQLKS
HHHHHHHHHHHHHHHCCCCEECCCCCEEEECCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]