The gene/protein map for NC_008358 is currently unavailable.
Definition Hyphomonas neptunium ATCC 15444 chromosome, complete genome.
Accession NC_008358
Length 3,705,021

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The map label for this gene is fadB1 [H]

Identifier: 114797149

GI number: 114797149

Start: 1885030

End: 1885806

Strand: Reverse

Name: fadB1 [H]

Synonym: HNE_1827

Alternate gene names: 114797149

Gene position: 1885806-1885030 (Counterclockwise)

Preceding gene: 114799926

Following gene: 114798417

Centisome position: 50.9

GC content: 57.27

Gene sequence:

>777_bases
ATGACCGATTACAAGACGATTACGTTTGAGCAGAAGGGCCGCGTAGCCCTGGTGACCCTCAATCGCCCTGACGCGCTCAA
TGCACTGAACGCTGAAGTTATGCAGGAAGTGGTGGATTGTTTCGCTGCGATTGATCGCAACAAGGACATTGCCGTCAGCG
TCCTGACCGGGGCCGGGCGGGCGTTTGCCGCTGGCGCTGACATCAAGGAAATGCAGCCGCAATCTTTCTCTGACATGTAT
GTGGAAGACTATTTCGCAGGCTGGGACCGTTTTGCGGCTTCGCGCAAGCCGGTTATTGCTGCGGTTAATGGCTTCGCGCT
GGGCGGCGGATGCGAACTCGCGATGATGTGTGACCTGATCATTGCGTCTGATAAAGCCAAGTTCGGTCAGCCCGAAATCA
AGCTCGGCGTGACACCGGGTATGGGCGGCTCCATCCGTCTGACGAAAGCTGTCGGCAAGGCCAAGGCTATGGATCTCGTA
CTCACAGGGCGGATGATTGACGGCACTGAAGCCGACCGGATCGGCCTTGTTTCCCGCGTTGTGCCTCATGATACGTTGAT
GGAGGTTGCACTGGCGGCGGCAGAAGAGATCGCGGCATTCTCCGTGCCTTCGTTGATGGCGGCCAAGGAAATGGTTGCCC
GCGCGCTAGAACTTCCGACAACGGAAGGGGTGAAATTCGAACGCCGCCTGTTCCAGGGCCTGTTTGGCACTGCCGACCAG
AAAGAAGGCATGAGCGCATTCAGTGAGAAGCGCCCTGCAAAGTTTGAGGACAAGTAA

Upstream 100 bases:

>100_bases
CGTGCGCTTCTGGACCAAGATCAAGACAATCACGCAGCGCTGGCCCGAGGGCGACATCGGCGACCAGGCGTTCGTCATTC
CGACTATGGGGTAAACCGAC

Downstream 100 bases:

>100_bases
GATGACCAAGATCGCCTTCATCGGCCTCGGCAACATGGGCGGTGGCATGTGCGCCAACCTCGTGAAGGCGGGACATGCGG
TGGCCGCCTTTGACCTGAAC

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MTDYKTITFEQKGRVALVTLNRPDALNALNAEVMQEVVDCFAAIDRNKDIAVSVLTGAGRAFAAGADIKEMQPQSFSDMY
VEDYFAGWDRFAASRKPVIAAVNGFALGGGCELAMMCDLIIASDKAKFGQPEIKLGVTPGMGGSIRLTKAVGKAKAMDLV
LTGRMIDGTEADRIGLVSRVVPHDTLMEVALAAAEEIAAFSVPSLMAAKEMVARALELPTTEGVKFERRLFQGLFGTADQ
KEGMSAFSEKRPAKFEDK

Sequences:

>Translated_258_residues
MTDYKTITFEQKGRVALVTLNRPDALNALNAEVMQEVVDCFAAIDRNKDIAVSVLTGAGRAFAAGADIKEMQPQSFSDMY
VEDYFAGWDRFAASRKPVIAAVNGFALGGGCELAMMCDLIIASDKAKFGQPEIKLGVTPGMGGSIRLTKAVGKAKAMDLV
LTGRMIDGTEADRIGLVSRVVPHDTLMEVALAAAEEIAAFSVPSLMAAKEMVARALELPTTEGVKFERRLFQGLFGTADQ
KEGMSAFSEKRPAKFEDK
>Mature_257_residues
TDYKTITFEQKGRVALVTLNRPDALNALNAEVMQEVVDCFAAIDRNKDIAVSVLTGAGRAFAAGADIKEMQPQSFSDMYV
EDYFAGWDRFAASRKPVIAAVNGFALGGGCELAMMCDLIIASDKAKFGQPEIKLGVTPGMGGSIRLTKAVGKAKAMDLVL
TGRMIDGTEADRIGLVSRVVPHDTLMEVALAAAEEIAAFSVPSLMAAKEMVARALELPTTEGVKFERRLFQGLFGTADQK
EGMSAFSEKRPAKFEDK

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=259, Percent_Identity=49.8069498069498, Blast_Score=251, Evalue=4e-67,
Organism=Homo sapiens, GI70995211, Length=263, Percent_Identity=31.1787072243346, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI31542718, Length=243, Percent_Identity=30.4526748971193, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI4502327, Length=262, Percent_Identity=30.5343511450382, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI20127408, Length=183, Percent_Identity=36.6120218579235, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI25453481, Length=261, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI51538573, Length=261, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4757968, Length=261, Percent_Identity=27.2030651340996, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI49355787, Length=261, Percent_Identity=27.2030651340996, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI4757966, Length=250, Percent_Identity=28, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI51538581, Length=250, Percent_Identity=28, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI68989263, Length=175, Percent_Identity=33.7142857142857, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI37594469, Length=222, Percent_Identity=28.3783783783784, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI37594471, Length=222, Percent_Identity=28.3783783783784, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI150378541, Length=246, Percent_Identity=29.2682926829268, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI45643119, Length=221, Percent_Identity=27.1493212669683, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260275230, Length=221, Percent_Identity=27.1493212669683, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI260274832, Length=221, Percent_Identity=27.1493212669683, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI221136756, Length=261, Percent_Identity=26.4367816091954, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI221136753, Length=261, Percent_Identity=26.4367816091954, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI221307494, Length=261, Percent_Identity=26.4367816091954, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI116235487, Length=197, Percent_Identity=30.9644670050761, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI213417737, Length=233, Percent_Identity=24.8927038626609, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI157694516, Length=233, Percent_Identity=24.8927038626609, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI62530384, Length=209, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI261878539, Length=83, Percent_Identity=40.9638554216867, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787659, Length=252, Percent_Identity=42.8571428571429, Blast_Score=205, Evalue=2e-54,
Organism=Escherichia coli, GI221142681, Length=253, Percent_Identity=35.1778656126482, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1787660, Length=259, Percent_Identity=35.5212355212355, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1790281, Length=188, Percent_Identity=32.4468085106383, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=31.1284046692607, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788682, Length=197, Percent_Identity=32.994923857868, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082183, Length=258, Percent_Identity=27.1317829457364, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554946, Length=248, Percent_Identity=49.5967741935484, Blast_Score=245, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI25145438, Length=252, Percent_Identity=46.4285714285714, Blast_Score=226, Evalue=8e-60,
Organism=Caenorhabditis elegans, GI17540306, Length=237, Percent_Identity=36.2869198312236, Blast_Score=127, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17560910, Length=261, Percent_Identity=30.2681992337165, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17540714, Length=185, Percent_Identity=35.6756756756757, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17558304, Length=215, Percent_Identity=30.6976744186047, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17549921, Length=207, Percent_Identity=31.4009661835749, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI25144276, Length=217, Percent_Identity=33.1797235023041, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508953, Length=217, Percent_Identity=33.1797235023041, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17508951, Length=217, Percent_Identity=33.1797235023041, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25144160, Length=222, Percent_Identity=30.1801801801802, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25144157, Length=222, Percent_Identity=30.1801801801802, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17534483, Length=188, Percent_Identity=31.9148936170213, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17536985, Length=276, Percent_Identity=26.8115942028986, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=225, Percent_Identity=27.5555555555556, Blast_Score=86, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320241, Length=199, Percent_Identity=27.1356783919598, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=53.0612244897959, Blast_Score=264, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=53.0612244897959, Blast_Score=264, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24650670, Length=212, Percent_Identity=34.4339622641509, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653139, Length=245, Percent_Identity=33.0612244897959, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI21357171, Length=212, Percent_Identity=33.0188679245283, Blast_Score=118, Evalue=5e-27,
Organism=Drosophila melanogaster, GI19922422, Length=248, Percent_Identity=27.8225806451613, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI19920382, Length=238, Percent_Identity=32.3529411764706, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24654903, Length=213, Percent_Identity=27.2300469483568, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19921000, Length=174, Percent_Identity=35.632183908046, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571729, Length=193, Percent_Identity=27.979274611399, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28571730, Length=193, Percent_Identity=27.979274611399, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583077, Length=174, Percent_Identity=35.632183908046, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583079, Length=174, Percent_Identity=35.632183908046, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24583165, Length=178, Percent_Identity=26.9662921348315, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19921018, Length=182, Percent_Identity=25.8241758241758, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27726; Mature: 27595

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTDYKTITFEQKGRVALVTLNRPDALNALNAEVMQEVVDCFAAIDRNKDIAVSVLTGAGR
CCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AFAAGADIKEMQPQSFSDMYVEDYFAGWDRFAASRKPVIAAVNGFALGGGCELAMMCDLI
EEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCHHHHHHHHH
IASDKAKFGQPEIKLGVTPGMGGSIRLTKAVGKAKAMDLVLTGRMIDGTEADRIGLVSRV
HCCCCCCCCCCCEEEEECCCCCCCEEEHHHHCCHHHEEEEEECCEECCCCCHHHHHHHHH
VPHDTLMEVALAAAEEIAAFSVPSLMAAKEMVARALELPTTEGVKFERRLFQGLFGTADQ
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
KEGMSAFSEKRPAKFEDK
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDYKTITFEQKGRVALVTLNRPDALNALNAEVMQEVVDCFAAIDRNKDIAVSVLTGAGR
CCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
AFAAGADIKEMQPQSFSDMYVEDYFAGWDRFAASRKPVIAAVNGFALGGGCELAMMCDLI
EEECCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCEEECCCCHHHHHHHHH
IASDKAKFGQPEIKLGVTPGMGGSIRLTKAVGKAKAMDLVLTGRMIDGTEADRIGLVSRV
HCCCCCCCCCCCEEEEECCCCCCCEEEHHHHCCHHHEEEEEECCEECCCCCHHHHHHHHH
VPHDTLMEVALAAAEEIAAFSVPSLMAAKEMVARALELPTTEGVKFERRLFQGLFGTADQ
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
KEGMSAFSEKRPAKFEDK
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]