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The map label for this gene is sufC [H]

Identifier: 114797142

GI number: 114797142

Start: 2774502

End: 2775263

Strand: Reverse

Name: sufC [H]

Synonym: HNE_2616

Alternate gene names: 114797142

Gene position: 2775263-2774502 (Counterclockwise)

Preceding gene: 114800533

Following gene: 114797340

Centisome position: 74.91

GC content: 62.2

Gene sequence:

>762_bases
ATGTTGAAGATCGAAAATCTGAGCGCCACCGTTGGTGAGCCTGACGCCGCAAAGACCATCATCAATGGTCTCTCGCTGGA
AGTGCCTGCGGGCGAAGTTCACGCGATCATGGGGCCGAACGGAGCAGGGAAATCCACCCTCTCCTATGTTCTCACCGGCC
GTGAAGGCTATGAGGTCACCGGCGGCAGCGCCACGCTCGACGGGCAGGACATCCTCGCCCTGGACCCGGAAGACCGCGCC
TCCGCCGGCCTCTTCCTGTCTTTCCAATACCCCATCGAAATCCCCGGCGTGCCGGTGATGACCTTCGTGCGCACCGCCAT
GAACGCCCAGCGCAAGGCGCGCGGCGAGCCGGAAATCTCCGCGCCGGACTATCTGAAAAAGTCGCGCGATGTGGCCAAGA
TGCTGAACCTGGACGCCGATATGCTGAAGCGCCCGGTCAATGTCGGCTTTTCGGGCGGCGAGAAAAAGCGCCTCGAAATC
TATCAGATGCTGATGCTGGAGCCCCGCTTCATGGTGCTCGACGAGACCGATTCCGGCCTCGACATTGACGCCCTGCGCAC
CGTCGCCGAGGGCGTCAACGCGCTGCGCGCGCCAGAGCGCGGCATGCTCGTCATCACCCACTATCAGCGCCTGCTCGACT
ATATCAAACCGGACAAGGTGCACGTTCTGGCCAAGGGCCGTATCATCAAGTCCGGCGGGCCGGAACTTGCTTTGCGCCTT
GAAAAAGAGGGCTATGACGGCGTGCTCGCGGAGGCTGTGTGA

Upstream 100 bases:

>100_bases
TACGGCCAAACCCGGCCTGCATGGCAGTCATCTGCCCTAAGGCGCGGCTTTTCCGCGCTTTGCGCTTTCAAATCATCGCG
GGGCGCCCTAAATCCCCGCC

Downstream 100 bases:

>100_bases
GCACCGCCCTGAAGGATATGATCCGCAATCCAACCGTTGCGGAACTTGAACTGGTCGCGCGCTACGCCGCCCTGAAGCCG
GACCCGCGCCGGGAACGCCT

Product: FeS assembly ATPase SufC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MLKIENLSATVGEPDAAKTIINGLSLEVPAGEVHAIMGPNGAGKSTLSYVLTGREGYEVTGGSATLDGQDILALDPEDRA
SAGLFLSFQYPIEIPGVPVMTFVRTAMNAQRKARGEPEISAPDYLKKSRDVAKMLNLDADMLKRPVNVGFSGGEKKRLEI
YQMLMLEPRFMVLDETDSGLDIDALRTVAEGVNALRAPERGMLVITHYQRLLDYIKPDKVHVLAKGRIIKSGGPELALRL
EKEGYDGVLAEAV

Sequences:

>Translated_253_residues
MLKIENLSATVGEPDAAKTIINGLSLEVPAGEVHAIMGPNGAGKSTLSYVLTGREGYEVTGGSATLDGQDILALDPEDRA
SAGLFLSFQYPIEIPGVPVMTFVRTAMNAQRKARGEPEISAPDYLKKSRDVAKMLNLDADMLKRPVNVGFSGGEKKRLEI
YQMLMLEPRFMVLDETDSGLDIDALRTVAEGVNALRAPERGMLVITHYQRLLDYIKPDKVHVLAKGRIIKSGGPELALRL
EKEGYDGVLAEAV
>Mature_253_residues
MLKIENLSATVGEPDAAKTIINGLSLEVPAGEVHAIMGPNGAGKSTLSYVLTGREGYEVTGGSATLDGQDILALDPEDRA
SAGLFLSFQYPIEIPGVPVMTFVRTAMNAQRKARGEPEISAPDYLKKSRDVAKMLNLDADMLKRPVNVGFSGGEKKRLEI
YQMLMLEPRFMVLDETDSGLDIDALRTVAEGVNALRAPERGMLVITHYQRLLDYIKPDKVHVLAKGRIIKSGGPELALRL
EKEGYDGVLAEAV

Specific function: Has low ATPase activity. The SufBCD complex acts synergistically with SufE to stimulate the cysteine desulfurase activity of SufS. The SufBCD complex contributes to the assembly or repair of oxygen-labile iron-sulfur clusters under oxidative stress. May f

COG id: COG0396

COG function: function code O; ABC-type transport system involved in Fe-S cluster assembly, ATPase component

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI156105685, Length=222, Percent_Identity=29.7297297297297, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI171184400, Length=226, Percent_Identity=30.0884955752212, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI148612844, Length=227, Percent_Identity=30.8370044052863, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI255708477, Length=227, Percent_Identity=30.8370044052863, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI42741659, Length=221, Percent_Identity=28.0542986425339, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI21536378, Length=242, Percent_Identity=27.6859504132231, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1787972, Length=251, Percent_Identity=56.1752988047809, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI48994883, Length=239, Percent_Identity=28.4518828451883, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789864, Length=231, Percent_Identity=26.4069264069264, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787370, Length=221, Percent_Identity=26.6968325791855, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1788761, Length=240, Percent_Identity=24.5833333333333, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786319, Length=191, Percent_Identity=31.413612565445, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788225, Length=224, Percent_Identity=27.2321428571429, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786398, Length=233, Percent_Identity=26.1802575107296, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787029, Length=244, Percent_Identity=25.8196721311475, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082267, Length=175, Percent_Identity=29.1428571428571, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790525, Length=218, Percent_Identity=28.8990825688073, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=29.1866028708134, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789891, Length=216, Percent_Identity=26.8518518518519, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787143, Length=216, Percent_Identity=25.9259259259259, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789672, Length=240, Percent_Identity=26.25, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787500, Length=240, Percent_Identity=25.4166666666667, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1789593, Length=221, Percent_Identity=23.0769230769231, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788506, Length=239, Percent_Identity=26.3598326359833, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1790467, Length=236, Percent_Identity=27.1186440677966, Blast_Score=61, Evalue=6e-11,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=27.0142180094787, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=227, Percent_Identity=30.3964757709251, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=226, Percent_Identity=31.4159292035398, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI193209708, Length=220, Percent_Identity=29.0909090909091, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=238, Percent_Identity=27.7310924369748, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17543740, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115535101, Length=243, Percent_Identity=30.4526748971193, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71984940, Length=215, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI212646699, Length=223, Percent_Identity=29.5964125560538, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193208177, Length=226, Percent_Identity=26.5486725663717, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71992290, Length=227, Percent_Identity=26.8722466960352, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319856, Length=259, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85724864, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580555, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI85816269, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24580553, Length=238, Percent_Identity=31.0924369747899, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24641565, Length=232, Percent_Identity=27.5862068965517, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28574533, Length=238, Percent_Identity=27.3109243697479, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010230 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 27423; Mature: 27423

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIENLSATVGEPDAAKTIINGLSLEVPAGEVHAIMGPNGAGKSTLSYVLTGREGYEVT
CEEECCCCCCCCCCHHHHHHHCCCEEECCCCCEEEEECCCCCCCCEEEEEEECCCCEEEE
GGSATLDGQDILALDPEDRASAGLFLSFQYPIEIPGVPVMTFVRTAMNAQRKARGEPEIS
CCCEEECCCEEEEECCCCCCCCCEEEEEECCEECCCCHHHHHHHHHHHHHHHHCCCCCCC
APDYLKKSRDVAKMLNLDADMLKRPVNVGFSGGEKKRLEIYQMLMLEPRFMVLDETDSGL
CCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
DIDALRTVAEGVNALRAPERGMLVITHYQRLLDYIKPDKVHVLAKGRIIKSGGPELALRL
CHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCEEEEEEECEEEECCCCEEEEEE
EKEGYDGVLAEAV
ECCCCCCCHHCCC
>Mature Secondary Structure
MLKIENLSATVGEPDAAKTIINGLSLEVPAGEVHAIMGPNGAGKSTLSYVLTGREGYEVT
CEEECCCCCCCCCCHHHHHHHCCCEEECCCCCEEEEECCCCCCCCEEEEEEECCCCEEEE
GGSATLDGQDILALDPEDRASAGLFLSFQYPIEIPGVPVMTFVRTAMNAQRKARGEPEIS
CCCEEECCCEEEEECCCCCCCCCEEEEEECCEECCCCHHHHHHHHHHHHHHHHCCCCCCC
APDYLKKSRDVAKMLNLDADMLKRPVNVGFSGGEKKRLEIYQMLMLEPRFMVLDETDSGL
CCHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCC
DIDALRTVAEGVNALRAPERGMLVITHYQRLLDYIKPDKVHVLAKGRIIKSGGPELALRL
CHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCEEEEEEECEEEECCCCEEEEEE
EKEGYDGVLAEAV
ECCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 10322040 [H]