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The map label for this gene is ftsK2 [H]

Identifier: 114332438

GI number: 114332438

Start: 2616631

End: 2618937

Strand: Direct

Name: ftsK2 [H]

Synonym: Neut_2488

Alternate gene names: 114332438

Gene position: 2616631-2618937 (Clockwise)

Preceding gene: 114332437

Following gene: 114332439

Centisome position: 98.33

GC content: 51.19

Gene sequence:

>2307_bases
ATGAGTTTCACGGACAAACCGATGGCGAAAAAAATTGCCAGCAATCCTTTGCCACCCAGAACCAGCCGATTGTTACGTGA
AGCAGTTTCTCTGGTGTTGGGTGGAATCGCACTTTACCTCACCCTGATTTTAATCAGCTTTGATCGTACCGATCCAGGCT
GGTCGCATAGCGGCACATTCCAGCAGATCAGTAATGCAGGGGGTAGTGCCGGTGCGTGGCTGGCAGATATGATGCTTTAT
TTTTTCGGTATTTCAGCATGGTGGTGGGTAATATTTTTTTTCGCCACTGTCTGGTGGGGTTATCGACGCATTGATATTGC
CAGCGTATATGATCCACGTGTACTCATGCTGTCTTTTACAGGATTTATCACTTTACTGACCGCCAGCAGTGGAATTGAGG
CGCTGCGTTTCCATACGTTGCGCCTATCACTTCCGCTGGCTCCCGGTGGCCTGCTGGGAGAAATGCTCAGCAAACAGCTA
TCGTTATTGCTCGGTTTTACCGGCGCGACACTGGCTCTGATGATTATTTTTGCAATCGGGCTCAGTTTGTTTTCCGGACT
GTCATGGGTGCGCCTGTCCGAAAAAATCGGTGGTGCAGTCGAGGCCGCCTGTTTTTCTGTCAGGGATGCATGTGTGAGAT
GGCTGGATCAGCGGGCTGGAAGGGTTTTGTCCGGTGTGTCGGAGTTTCAGACTGGCGAGATCAGGAAGCAATCCCTTCCC
TCCGTTCCGCTGCATATTGAAATGCCTGAAACTGCTATTCCCAAATCTCAGCGGGTCAGCAACAAGGAAAAACAGATTCC
GTTGTTTTCCAATTCACCCGATGCGATTCTCCCCCCGCTTTATTTGCTGGATGAACCGCAGGATAACGTTGAAGTATTAT
CCAGTGATAAACTGGAATATACCTCGCGCCTAATTGAACGCAGGCTGATGGAGTTTGGTGTGGAAGTCAAGGTGGTAGCT
GCCTACCCTGGCCCGGTCATTACACGTTATGAAATCGAACCGGCTGTTGGCGTCAAAGGTAATCAGATCGTCAATCTAGT
CAGGGATCTGGCGCGTGCCTTGACGGTCGCCAGTATTCGTGTTGTGGAAACAATTCCGGGTAAAACCGTCATGGGACTGG
AAATCCCCAATCCGAAACGCCAGATGGTTCGCCTGCATGAGATTCTTGCATCCAAAGTCTATGCGGATAACTCGTCTCCT
CTGACCATTGCGCTTGGCAAGGATATCAGTGGGCGCCCTGTGGTGTCTGATCTGGCTAAAATGCCGCATGCCCTGGTGGC
TGGCACGACCGGTTCCGGCAAATCTGTCGCGATCAACGCTGTCATTCTAAGCCTGGTCTACAAAGCTTCACCGGATAATA
TCCGCCTGATTTTGATTGACCCGAAAATGCTGGAATTATCCGTCTATGAAGGTATTCCGCATTTGTTGACCCCAGTAGTT
ACCGATATGCGTGATGCTGCCAGTGCGCTCAACTGGTGCGTTGCTGAAATGGAGCGACGCTACAAGTTGATGTCGGCTCT
GGGCGTGCGCAACCTGGCCGGTTACAACCAGAAAGTGCGAGAAGCGGCAAAGAATGAGGAGCCGCTGACCAATCCGCTCA
GCTCGGTACCCGATTCTCCCGAACTGCTGGAAGAAATGCCTTTGATCGTGGTGGTGATCGATGAGCTTGCTGATCTGATG
ATGATTGTGGGTAAGAAAGTCGAGAAGCTGATTGCACGGCTTGCCCAGAAAGCACGCGCTGCCGGTATCCATTTGCTGCT
TGCGACACAACGCCCGTCGGTGGATGTGATTACGGGGTTGATCAAGGCCAATATCCCAACACGTATCGCATTCCAGGTTT
CCAGTAAGATTGATTCCCGGACCATTCTTGATCAAATGGGGGCAGAAGCACTGCTTGGACAAGGTGACATGCTTTATCTT
CCACCTGGCAGCGGCTACCCCCAGCGTGTACATGGTGCATTTGTGGCAGATCATGAAGTGCACAAGGTGGTGGAATACCT
TAAACAGCATGGTGAGGCGAACTACGTTGAGGAAATTCTTCAGGCTGGTGAGGAGGGAGGAGGCACTGATGAAAATAGCA
GTGATAACAGCAAATCTGCTGGTGGAGAAGCGGACCCGCTCTATGACGAAGCAGTCGGTATCGTGATCAAATCCCGTCGC
GCCTCAATTTCACTGGTGCAACGGCAGTTGCGTATTGGGTACAACCGTGCTGCCCGGTTGATTGAAGAAATGGAGCGTAC
CGGTCTCGTTTCCAGCATGCAAAGTAATGGTAACCGGGAAGTACTGGTTCCCGAGCGAAATGAATAA

Upstream 100 bases:

>100_bases
GAAAATCGTTCTCATAGCGGCGTAGTTTTTTCTGTGGCACATAAAAGCACAGCTGGTTTTGTGAACCGGCCTGAATTTTG
AAGTTAAAGATGATGTATAC

Downstream 100 bases:

>100_bases
GTAAAATCTGGTTCATACAGTTTCGTTTCCGATCAATCAACTTAAACAGATAATTTATCATGTCCCGTTTACTGTTCGTT
TTCGCGTTATCAATCTGTCT

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 768; Mature: 767

Protein sequence:

>768_residues
MSFTDKPMAKKIASNPLPPRTSRLLREAVSLVLGGIALYLTLILISFDRTDPGWSHSGTFQQISNAGGSAGAWLADMMLY
FFGISAWWWVIFFFATVWWGYRRIDIASVYDPRVLMLSFTGFITLLTASSGIEALRFHTLRLSLPLAPGGLLGEMLSKQL
SLLLGFTGATLALMIIFAIGLSLFSGLSWVRLSEKIGGAVEAACFSVRDACVRWLDQRAGRVLSGVSEFQTGEIRKQSLP
SVPLHIEMPETAIPKSQRVSNKEKQIPLFSNSPDAILPPLYLLDEPQDNVEVLSSDKLEYTSRLIERRLMEFGVEVKVVA
AYPGPVITRYEIEPAVGVKGNQIVNLVRDLARALTVASIRVVETIPGKTVMGLEIPNPKRQMVRLHEILASKVYADNSSP
LTIALGKDISGRPVVSDLAKMPHALVAGTTGSGKSVAINAVILSLVYKASPDNIRLILIDPKMLELSVYEGIPHLLTPVV
TDMRDAASALNWCVAEMERRYKLMSALGVRNLAGYNQKVREAAKNEEPLTNPLSSVPDSPELLEEMPLIVVVIDELADLM
MIVGKKVEKLIARLAQKARAAGIHLLLATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYL
PPGSGYPQRVHGAFVADHEVHKVVEYLKQHGEANYVEEILQAGEEGGGTDENSSDNSKSAGGEADPLYDEAVGIVIKSRR
ASISLVQRQLRIGYNRAARLIEEMERTGLVSSMQSNGNREVLVPERNE

Sequences:

>Translated_768_residues
MSFTDKPMAKKIASNPLPPRTSRLLREAVSLVLGGIALYLTLILISFDRTDPGWSHSGTFQQISNAGGSAGAWLADMMLY
FFGISAWWWVIFFFATVWWGYRRIDIASVYDPRVLMLSFTGFITLLTASSGIEALRFHTLRLSLPLAPGGLLGEMLSKQL
SLLLGFTGATLALMIIFAIGLSLFSGLSWVRLSEKIGGAVEAACFSVRDACVRWLDQRAGRVLSGVSEFQTGEIRKQSLP
SVPLHIEMPETAIPKSQRVSNKEKQIPLFSNSPDAILPPLYLLDEPQDNVEVLSSDKLEYTSRLIERRLMEFGVEVKVVA
AYPGPVITRYEIEPAVGVKGNQIVNLVRDLARALTVASIRVVETIPGKTVMGLEIPNPKRQMVRLHEILASKVYADNSSP
LTIALGKDISGRPVVSDLAKMPHALVAGTTGSGKSVAINAVILSLVYKASPDNIRLILIDPKMLELSVYEGIPHLLTPVV
TDMRDAASALNWCVAEMERRYKLMSALGVRNLAGYNQKVREAAKNEEPLTNPLSSVPDSPELLEEMPLIVVVIDELADLM
MIVGKKVEKLIARLAQKARAAGIHLLLATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYL
PPGSGYPQRVHGAFVADHEVHKVVEYLKQHGEANYVEEILQAGEEGGGTDENSSDNSKSAGGEADPLYDEAVGIVIKSRR
ASISLVQRQLRIGYNRAARLIEEMERTGLVSSMQSNGNREVLVPERNE
>Mature_767_residues
SFTDKPMAKKIASNPLPPRTSRLLREAVSLVLGGIALYLTLILISFDRTDPGWSHSGTFQQISNAGGSAGAWLADMMLYF
FGISAWWWVIFFFATVWWGYRRIDIASVYDPRVLMLSFTGFITLLTASSGIEALRFHTLRLSLPLAPGGLLGEMLSKQLS
LLLGFTGATLALMIIFAIGLSLFSGLSWVRLSEKIGGAVEAACFSVRDACVRWLDQRAGRVLSGVSEFQTGEIRKQSLPS
VPLHIEMPETAIPKSQRVSNKEKQIPLFSNSPDAILPPLYLLDEPQDNVEVLSSDKLEYTSRLIERRLMEFGVEVKVVAA
YPGPVITRYEIEPAVGVKGNQIVNLVRDLARALTVASIRVVETIPGKTVMGLEIPNPKRQMVRLHEILASKVYADNSSPL
TIALGKDISGRPVVSDLAKMPHALVAGTTGSGKSVAINAVILSLVYKASPDNIRLILIDPKMLELSVYEGIPHLLTPVVT
DMRDAASALNWCVAEMERRYKLMSALGVRNLAGYNQKVREAAKNEEPLTNPLSSVPDSPELLEEMPLIVVVIDELADLMM
IVGKKVEKLIARLAQKARAAGIHLLLATQRPSVDVITGLIKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLP
PGSGYPQRVHGAFVADHEVHKVVEYLKQHGEANYVEEILQAGEEGGGTDENSSDNSKSAGGEADPLYDEAVGIVIKSRRA
SISLVQRQLRIGYNRAARLIEEMERTGLVSSMQSNGNREVLVPERNE

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=503, Percent_Identity=62.8230616302187, Blast_Score=600, Evalue=1e-172,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 84006; Mature: 83874

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTDKPMAKKIASNPLPPRTSRLLREAVSLVLGGIALYLTLILISFDRTDPGWSHSGTF
CCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
QQISNAGGSAGAWLADMMLYFFGISAWWWVIFFFATVWWGYRRIDIASVYDPRVLMLSFT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCEEEEEHHH
GFITLLTASSGIEALRFHTLRLSLPLAPGGLLGEMLSKQLSLLLGFTGATLALMIIFAIG
HHHHHHHCCCCHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LSLFSGLSWVRLSEKIGGAVEAACFSVRDACVRWLDQRAGRVLSGVSEFQTGEIRKQSLP
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
SVPLHIEMPETAIPKSQRVSNKEKQIPLFSNSPDAILPPLYLLDEPQDNVEVLSSDKLEY
CCCEEEECCCHHCCCHHHCCCHHHCCCCCCCCCCCCCCCHHEECCCCCCHHHHCCCHHHH
TSRLIERRLMEFGVEVKVVAAYPGPVITRYEIEPAVGVKGNQIVNLVRDLARALTVASIR
HHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VVETIPGKTVMGLEIPNPKRQMVRLHEILASKVYADNSSPLTIALGKDISGRPVVSDLAK
EEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
MPHALVAGTTGSGKSVAINAVILSLVYKASPDNIRLILIDPKMLELSVYEGIPHLLTPVV
CCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHHHHCCHHHHHHHH
TDMRDAASALNWCVAEMERRYKLMSALGVRNLAGYNQKVREAAKNEEPLTNPLSSVPDSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHCCCCCH
ELLEEMPLIVVVIDELADLMMIVGKKVEKLIARLAQKARAAGIHLLLATQRPSVDVITGL
HHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGSGYPQRVHGAFVADHEV
HHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHCCCCCEEEECCCCCCCHHHCCCCCCHHHH
HKVVEYLKQHGEANYVEEILQAGEEGGGTDENSSDNSKSAGGEADPLYDEAVGIVIKSRR
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEECCCH
ASISLVQRQLRIGYNRAARLIEEMERTGLVSSMQSNGNREVLVPERNE
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC
>Mature Secondary Structure 
SFTDKPMAKKIASNPLPPRTSRLLREAVSLVLGGIALYLTLILISFDRTDPGWSHSGTF
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
QQISNAGGSAGAWLADMMLYFFGISAWWWVIFFFATVWWGYRRIDIASVYDPRVLMLSFT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEEEEECCCCEEEEEHHH
GFITLLTASSGIEALRFHTLRLSLPLAPGGLLGEMLSKQLSLLLGFTGATLALMIIFAIG
HHHHHHHCCCCHHHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LSLFSGLSWVRLSEKIGGAVEAACFSVRDACVRWLDQRAGRVLSGVSEFQTGEIRKQSLP
HHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
SVPLHIEMPETAIPKSQRVSNKEKQIPLFSNSPDAILPPLYLLDEPQDNVEVLSSDKLEY
CCCEEEECCCHHCCCHHHCCCHHHCCCCCCCCCCCCCCCHHEECCCCCCHHHHCCCHHHH
TSRLIERRLMEFGVEVKVVAAYPGPVITRYEIEPAVGVKGNQIVNLVRDLARALTVASIR
HHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VVETIPGKTVMGLEIPNPKRQMVRLHEILASKVYADNSSPLTIALGKDISGRPVVSDLAK
EEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHH
MPHALVAGTTGSGKSVAINAVILSLVYKASPDNIRLILIDPKMLELSVYEGIPHLLTPVV
CCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEHHHHHCCHHHHHHHH
TDMRDAASALNWCVAEMERRYKLMSALGVRNLAGYNQKVREAAKNEEPLTNPLSSVPDSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHCCCCCH
ELLEEMPLIVVVIDELADLMMIVGKKVEKLIARLAQKARAAGIHLLLATQRPSVDVITGL
HHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHH
IKANIPTRIAFQVSSKIDSRTILDQMGAEALLGQGDMLYLPPGSGYPQRVHGAFVADHEV
HHCCCCCEEEEEEHHCCHHHHHHHHHCHHHHCCCCCEEEECCCCCCCHHHCCCCCCHHHH
HKVVEYLKQHGEANYVEEILQAGEEGGGTDENSSDNSKSAGGEADPLYDEAVGIVIKSRR
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEECCCH
ASISLVQRQLRIGYNRAARLIEEMERTGLVSSMQSNGNREVLVPERNE
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]