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The map label for this gene is lolA

Identifier: 114332439

GI number: 114332439

Start: 2618997

End: 2619617

Strand: Direct

Name: lolA

Synonym: Neut_2489

Alternate gene names: 114332439

Gene position: 2618997-2619617 (Clockwise)

Preceding gene: 114332438

Following gene: 114332440

Centisome position: 98.42

GC content: 47.99

Gene sequence:

>621_bases
ATGTCCCGTTTACTGTTCGTTTTCGCGTTATCAATCTGTCTGTTACCCGTGTCAGCAAAGGCAAGTGCCGTTGAAAGCCT
GAAAGCTTTCGTCAATAAAGCGCTGACCTTCCGAGCCGATTTTTCACAGACACTACTCGACAAAAACTTCCAGGTCGTTA
AAAAAGCCAGTGGCAGCATGATGTTTGAGCGCCCTGGTAAATTTCGCTGGGTATACGACCAGCCCTATCAGCAGCTGATT
GTCGGTGATGGTAAGCAGGTGTGGTTTTATGATCAGGACCTTGCGCAGGTTACAGTACATCGGCTTGATCAAACTTTGGG
TAGCACCCCGGCTGCACTGCTCGCAGGAGGTAATACCATCGAACGTGATTTTAATCTGCAGGAAATCGATGTGCAGGGCG
AAACAGAATGGCTGGAGGCAATTCCCAAAAATCAGGAAAACGCATTTGAGCTGATCCGGCTGGGTTTCTCACAAACAGGC
ATGTTGCGTGAAATGATTTTGCGCGACAGTTTTGATCAGGTGACATGGTTAATTTTTTCCGGGACAGAACAAAATCCAGT
ACTCACGCCTGATTTATTCCAGTTTACGCCGCCTGAAGGGGTGGACGTGATCAGTGACTGA

Upstream 100 bases:

>100_bases
ATGGTAACCGGGAAGTACTGGTTCCCGAGCGAAATGAATAAGTAAAATCTGGTTCATACAGTTTCGTTTCCGATCAATCA
ACTTAAACAGATAATTTATC

Downstream 100 bases:

>100_bases
TTTTTGTTCTACGCATAATCCAGCAGCTCCGCTGGCAGAAAGGTTGCGCCCGCAGACCTTGGATAATGTTATCGGACAAC
CTCATCTGTTGGGTTCCGGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSRLLFVFALSICLLPVSAKASAVESLKAFVNKALTFRADFSQTLLDKNFQVVKKASGSMMFERPGKFRWVYDQPYQQLI
VGDGKQVWFYDQDLAQVTVHRLDQTLGSTPAALLAGGNTIERDFNLQEIDVQGETEWLEAIPKNQENAFELIRLGFSQTG
MLREMILRDSFDQVTWLIFSGTEQNPVLTPDLFQFTPPEGVDVISD

Sequences:

>Translated_206_residues
MSRLLFVFALSICLLPVSAKASAVESLKAFVNKALTFRADFSQTLLDKNFQVVKKASGSMMFERPGKFRWVYDQPYQQLI
VGDGKQVWFYDQDLAQVTVHRLDQTLGSTPAALLAGGNTIERDFNLQEIDVQGETEWLEAIPKNQENAFELIRLGFSQTG
MLREMILRDSFDQVTWLIFSGTEQNPVLTPDLFQFTPPEGVDVISD
>Mature_205_residues
SRLLFVFALSICLLPVSAKASAVESLKAFVNKALTFRADFSQTLLDKNFQVVKKASGSMMFERPGKFRWVYDQPYQQLIV
GDGKQVWFYDQDLAQVTVHRLDQTLGSTPAALLAGGNTIERDFNLQEIDVQGETEWLEAIPKNQENAFELIRLGFSQTGM
LREMILRDSFDQVTWLIFSGTEQNPVLTPDLFQFTPPEGVDVISD

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=203, Percent_Identity=26.6009852216749, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_NITEC (Q0AD86)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748661.1
- ProteinModelPortal:   Q0AD86
- SMR:   Q0AD86
- STRING:   Q0AD86
- GeneID:   4273771
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2489
- NMPDR:   fig|335283.3.peg.1229
- eggNOG:   COG2834
- HOGENOM:   HBG688940
- OMA:   MELRDAF
- PhylomeDB:   Q0AD86
- ProtClustDB:   CLSK585616
- BioCyc:   NEUT335283:NEUT_2489-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23292; Mature: 23161

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLLFVFALSICLLPVSAKASAVESLKAFVNKALTFRADFSQTLLDKNFQVVKKASGSM
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHHCCHHHHHHCCCCE
MFERPGKFRWVYDQPYQQLIVGDGKQVWFYDQDLAQVTVHRLDQTLGSTPAALLAGGNTI
EEECCCCEEEEECCCHHHHEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEECCCEE
ERDFNLQEIDVQGETEWLEAIPKNQENAFELIRLGFSQTGMLREMILRDSFDQVTWLIFS
CCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEE
GTEQNPVLTPDLFQFTPPEGVDVISD
CCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SRLLFVFALSICLLPVSAKASAVESLKAFVNKALTFRADFSQTLLDKNFQVVKKASGSM
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEECCHHHHHHHCCHHHHHHCCCCE
MFERPGKFRWVYDQPYQQLIVGDGKQVWFYDQDLAQVTVHRLDQTLGSTPAALLAGGNTI
EEECCCCEEEEECCCHHHHEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEECCCEE
ERDFNLQEIDVQGETEWLEAIPKNQENAFELIRLGFSQTGMLREMILRDSFDQVTWLIFS
CCCCCEEEEECCCCHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEE
GTEQNPVLTPDLFQFTPPEGVDVISD
CCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA