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The map label for this gene is ssb [H]

Identifier: 114332412

GI number: 114332412

Start: 2579819

End: 2580286

Strand: Direct

Name: ssb [H]

Synonym: Neut_2461

Alternate gene names: 114332412

Gene position: 2579819-2580286 (Clockwise)

Preceding gene: 114332411

Following gene: 114332413

Centisome position: 96.95

GC content: 48.72

Gene sequence:

>468_bases
ATGGCTTCACTAAATAAAGTTATGTTGATTGGCAATCTTGGCCGCGATCCGGAAATCCGTTACATGCCCAGCGGCGATGC
CATGGCAAATCTGAATATTGCCACTACCGATACCTGGAAAGACAAGGGGGGCGAGAAACAGGAGCGCACCGAATGGCACC
GGATCGTTATGTTTGGCAAGCTGGCTGAGATTACTGGAGAATATCTGAAAAAAGGCTCACAGATTTATATCGAAGGTCGC
TTACAAACGCGCAAATGGACTGATAAATCCAACGTGGAACGCTATACCACCGAAATCGTCGCCGACCGTATGCAAATGCT
TGGTGGCCGCTCAGGTGGTGGCAGCGGTGGTAACTATGATCCACCAGCCGACCAAGGTAACGAATATTCAAGTAACACAC
CTGCTAAAACTGGCACTACAGGTAGCAGCACAGGTTTTGACGATATGGAAGACGATATCCCGTTTTAG

Upstream 100 bases:

>100_bases
GGCGCTTGTACTGGCCAATGAACAGGTGGCTTATCTGAAGGTTGATCTCAAGGGTTTTGATGAAGAAAAAGTGGTTCAGT
TATTGGAAGGAAATAGATAA

Downstream 100 bases:

>100_bases
CCAGTACCTATCAGGTAAATGCAAATAAACCCGGGCAAACTTATCGCTCGTCCGGGCTCCGGTTTTTATCTTCCACACAC
TGACCCTAACGTGTCAGTTG

Product: single-strand binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MASLNKVMLIGNLGRDPEIRYMPSGDAMANLNIATTDTWKDKGGEKQERTEWHRIVMFGKLAEITGEYLKKGSQIYIEGR
LQTRKWTDKSNVERYTTEIVADRMQMLGGRSGGGSGGNYDPPADQGNEYSSNTPAKTGTTGSSTGFDDMEDDIPF

Sequences:

>Translated_155_residues
MASLNKVMLIGNLGRDPEIRYMPSGDAMANLNIATTDTWKDKGGEKQERTEWHRIVMFGKLAEITGEYLKKGSQIYIEGR
LQTRKWTDKSNVERYTTEIVADRMQMLGGRSGGGSGGNYDPPADQGNEYSSNTPAKTGTTGSSTGFDDMEDDIPF
>Mature_154_residues
ASLNKVMLIGNLGRDPEIRYMPSGDAMANLNIATTDTWKDKGGEKQERTEWHRIVMFGKLAEITGEYLKKGSQIYIEGRL
QTRKWTDKSNVERYTTEIVADRMQMLGGRSGGGSGGNYDPPADQGNEYSSNTPAKTGTTGSSTGFDDMEDDIPF

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=116, Percent_Identity=34.4827586206897, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1790494, Length=121, Percent_Identity=63.6363636363636, Blast_Score=166, Evalue=5e-43,
Organism=Drosophila melanogaster, GI85725234, Length=101, Percent_Identity=31.6831683168317, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24647376, Length=101, Percent_Identity=31.6831683168317, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 17125; Mature: 16994

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLNKVMLIGNLGRDPEIRYMPSGDAMANLNIATTDTWKDKGGEKQERTEWHRIVMFGK
CCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LAEITGEYLKKGSQIYIEGRLQTRKWTDKSNVERYTTEIVADRMQMLGGRSGGGSGGNYD
HHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PPADQGNEYSSNTPAKTGTTGSSTGFDDMEDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASLNKVMLIGNLGRDPEIRYMPSGDAMANLNIATTDTWKDKGGEKQERTEWHRIVMFGK
CCCCEEEEEECCCCCCCEEEECCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHH
LAEITGEYLKKGSQIYIEGRLQTRKWTDKSNVERYTTEIVADRMQMLGGRSGGGSGGNYD
HHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PPADQGNEYSSNTPAKTGTTGSSTGFDDMEDDIPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]