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The map label for this gene is yeaD [H]

Identifier: 114332407

GI number: 114332407

Start: 2570220

End: 2571125

Strand: Reverse

Name: yeaD [H]

Synonym: Neut_2456

Alternate gene names: 114332407

Gene position: 2571125-2570220 (Counterclockwise)

Preceding gene: 114332409

Following gene: 114332406

Centisome position: 96.62

GC content: 48.57

Gene sequence:

>906_bases
ATGAATATCGAGCAACTAAATCAAAAATACGGAATTGGGGAGCAGGTAGTTTTTAAAGAGGGAGAAGGGGGTTTACCCTT
TATTCATATCAAGAATGAAAAGGCCAATGCACTGATCTCGATTTACGGCGGACAGGTGCTTGCATTCCGGCCGATACATG
CGCAAGACGATCTTCTGTTTTTAAGCAAGCGCGCCTATTATCAACAGGGCAAGGCAATCAAAGGCGGTGTGCCGATTTGC
TGGCCATGGTTTGGCCCGGATCCGGAAGGTAAAGGGCGATCAGCACATGGTTTTATGCGCAATCGCATGTGGGATGTCAT
CGAAACATCCACAACCCCGGAAAACGGCACTCGAATCGTACTGGGATCAACCGATACCGAAGAAACACGATCCATCTGGC
CACGCGCATTCATTTTGAGACTGGAAATTACCATTAGCGATACGCTCAATCTGGAGCTGATCACTCGCAATCCGGGCTCA
CAAGTATGTACGATCACACAGGCTTTTCATACCTACTTCAACGTGGGGGATATTCGGCAGACACATGTATCCAGCCTGGA
AAACACTCGCTATATTGATAAAGTGCACGATAACCTGGAAAAAAACCAGATCGGTGCTGTCACCATTGAGGCGGAAGTGG
ACCGAATTTACCAGTCAGTCGATAGCAATCTCATCATTCACGATACAGCTCGCAAACGCCGTATCCGCATCACTTCTAAA
GGGAACAGAACCGCCGTTGTGTGGAATCCCTGGGCAAAGATCTCGACAGAAATGGCAGATCTGGAAGATGATGATTACCT
GCGTTTTATTTGTGTGGAAACCACCAATGCCGCGACAGACCGGGTTCATATCCAGCCCGGCAGTGAGTTCCGGTTGGTTG
CCAATTACCGGATTGAGCAGGACTGA

Upstream 100 bases:

>100_bases
GCAGTAACCGTTTAAGTTTATCATTCGCCACTGGCTGCAACCAAATACTTGACCTGACACCGATGGTTACAGCTTTTTTG
TATTTTTAAACGGGAGAATA

Downstream 100 bases:

>100_bases
CAGAAAATCTCCAGAATTTTCTGTTTGAAAACAAGGAAAAACAATGGCTCTAAAACTTAACATTATCACCTGTAGTACTC
GCCCCGGGCGCATCGGGCCT

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MNIEQLNQKYGIGEQVVFKEGEGGLPFIHIKNEKANALISIYGGQVLAFRPIHAQDDLLFLSKRAYYQQGKAIKGGVPIC
WPWFGPDPEGKGRSAHGFMRNRMWDVIETSTTPENGTRIVLGSTDTEETRSIWPRAFILRLEITISDTLNLELITRNPGS
QVCTITQAFHTYFNVGDIRQTHVSSLENTRYIDKVHDNLEKNQIGAVTIEAEVDRIYQSVDSNLIIHDTARKRRIRITSK
GNRTAVVWNPWAKISTEMADLEDDDYLRFICVETTNAATDRVHIQPGSEFRLVANYRIEQD

Sequences:

>Translated_301_residues
MNIEQLNQKYGIGEQVVFKEGEGGLPFIHIKNEKANALISIYGGQVLAFRPIHAQDDLLFLSKRAYYQQGKAIKGGVPIC
WPWFGPDPEGKGRSAHGFMRNRMWDVIETSTTPENGTRIVLGSTDTEETRSIWPRAFILRLEITISDTLNLELITRNPGS
QVCTITQAFHTYFNVGDIRQTHVSSLENTRYIDKVHDNLEKNQIGAVTIEAEVDRIYQSVDSNLIIHDTARKRRIRITSK
GNRTAVVWNPWAKISTEMADLEDDDYLRFICVETTNAATDRVHIQPGSEFRLVANYRIEQD
>Mature_301_residues
MNIEQLNQKYGIGEQVVFKEGEGGLPFIHIKNEKANALISIYGGQVLAFRPIHAQDDLLFLSKRAYYQQGKAIKGGVPIC
WPWFGPDPEGKGRSAHGFMRNRMWDVIETSTTPENGTRIVLGSTDTEETRSIWPRAFILRLEITISDTLNLELITRNPGS
QVCTITQAFHTYFNVGDIRQTHVSSLENTRYIDKVHDNLEKNQIGAVTIEAEVDRIYQSVDSNLIIHDTARKRRIRITSK
GNRTAVVWNPWAKISTEMADLEDDDYLRFICVETTNAATDRVHIQPGSEFRLVANYRIEQD

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=255, Percent_Identity=34.9019607843137, Blast_Score=159, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323746, Length=282, Percent_Identity=28.3687943262411, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19921284, Length=264, Percent_Identity=30.3030303030303, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28574481, Length=169, Percent_Identity=31.3609467455621, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 34280; Mature: 34280

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEQLNQKYGIGEQVVFKEGEGGLPFIHIKNEKANALISIYGGQVLAFRPIHAQDDLLF
CCHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCEEEEEECCCCCCCEEE
LSKRAYYQQGKAIKGGVPICWPWFGPDPEGKGRSAHGFMRNRMWDVIETSTTPENGTRIV
EEHHHHHHCCCEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCEEE
LGSTDTEETRSIWPRAFILRLEITISDTLNLELITRNPGSQVCTITQAFHTYFNVGDIRQ
EECCCCHHHHHHCCEEEEEEEEEEEECCEEEEEEECCCCCCEEEHHHHHHHHHCCCCCHH
THVSSLENTRYIDKVHDNLEKNQIGAVTIEAEVDRIYQSVDSNLIIHDTARKRRIRITSK
HHHHHHHCCHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCEEEEEEEC
GNRTAVVWNPWAKISTEMADLEDDDYLRFICVETTNAATDRVHIQPGSEFRLVANYRIEQ
CCEEEEEECCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEEEEEECC
D
C
>Mature Secondary Structure
MNIEQLNQKYGIGEQVVFKEGEGGLPFIHIKNEKANALISIYGGQVLAFRPIHAQDDLLF
CCHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCEEEEEECCEEEEEECCCCCCCEEE
LSKRAYYQQGKAIKGGVPICWPWFGPDPEGKGRSAHGFMRNRMWDVIETSTTPENGTRIV
EEHHHHHHCCCEEECCCCEEECCCCCCCCCCCCCCHHHHHHHHHHEEECCCCCCCCCEEE
LGSTDTEETRSIWPRAFILRLEITISDTLNLELITRNPGSQVCTITQAFHTYFNVGDIRQ
EECCCCHHHHHHCCEEEEEEEEEEEECCEEEEEEECCCCCCEEEHHHHHHHHHCCCCCHH
THVSSLENTRYIDKVHDNLEKNQIGAVTIEAEVDRIYQSVDSNLIIHDTARKRRIRITSK
HHHHHHHCCHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHCCCEEEEECCCCEEEEEEEC
GNRTAVVWNPWAKISTEMADLEDDDYLRFICVETTNAATDRVHIQPGSEFRLVANYRIEQ
CCEEEEEECCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEECCCCCEEEEEEEEECC
D
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]