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The map label for this gene is ttuD [H]

Identifier: 114332409

GI number: 114332409

Start: 2574232

End: 2575503

Strand: Reverse

Name: ttuD [H]

Synonym: Neut_2458

Alternate gene names: 114332409

Gene position: 2575503-2574232 (Counterclockwise)

Preceding gene: 114332410

Following gene: 114332407

Centisome position: 96.78

GC content: 54.25

Gene sequence:

>1272_bases
ATGAATCCGCGCGAACTTCTGCTTGATAGTTTTCATGCTGCTGTTAATGCAGCTGATCCGCTGAAAATTGTGCCTTGTCA
TCTGCCTGAACCGCCACGCGGGAACACGCTGGTGGTTGGTGCTGGCAAAGCGGCTGCCGCCATGGCGCGCGCAGTGGAAG
AGAACTGGCCAGCAGATCATCCCCTGGAAGGGATTGTGGTGACGCCTTATGGTCATGGTCTGGCGACGAACAACATCATG
GTGATTGAGGCCAGTCATCCGGTACCGGATACACAAGGTGAAATGGCAGCCCGCGCCATGCTGGAATCGGCACGCATACT
CACGCCAAATGATCTGCTGCTGGGACTGTTCAGTGGCGGGGGGTCCAGTCTGCTGTCTGCGCCCATTCCCGGAGTAACGC
TGGATGAACTGAAATCAATTACCCGCCAGTTATTGCGTTGTGGCGCGGCAATCCAGGAAATCAATATCGTGCGCAAGCAT
TTATCTGTCGTACTGGGTGGCAGATTGGCAGCCGCCAGCCGGGCATCGGTACACAGTCTGATCATCTCGGATGTCACCGA
TAACGATCCTTCCTCCATCGCATCCGGACCCTGTGCGCCAGATCCCTCCACCTGGCAGGATGTGCTGGCACTGATAGAGC
GTTATGCAATTAACATTGCTCCGCAAACCATGGGAATCCTGCAGAAAAATGTCAATACAGGCAGTAACGAAACCCCCAAA
CTAGGCGATCCGGTTTTCAGGAACGTGAAAAACCGGATAATCGCTACGGCGCGGCAATCACTCGCGGCGGCTGCACAGTT
TTTTCGTGCACAAGGCATTACACCGCTGATTCTCGGTGACACCGTAACCGGGGAGGCAAAGGAAATCGCCAAAATGCATG
CGGCCATCGCACGGGAAGTACGCCATTACAGCAACCCGTTTAAACCGCCTGTAGCCTTGATTTCCGGTGGAGAAACCACG
GTAACGGTAACAGGTTCTGGCAGGGGCGGGCGCAATGCCGAGTTTCTGCTCTCGCTCGCCATCGCACTCAATGGACTGGA
AGAAGTTTACGCATTGGCTTGCGATACTGACGGAATCGACGGCAACGGAACCAACGCCGGTGCAGTAATCACACCAGATA
CCCTCAATCGAGTAGAGCAGGCCGACGTTAATCCAGTAAGATTGCTTGATGACAATGATGCCTGGACTTTCTTTGACCAA
CTGGATGATCTGATTGTCACCGGCCCAACCCGCACCAATGTTAATGACTACCGGGTTGTTCTGGTTTTGTAG

Upstream 100 bases:

>100_bases
TCATCGCCGAGGGCACACCGGAAGCCGTGGCAGCGATGCCTGGCAGTTTTACCGGACAGTTTCTCCAGCCATTGCTTTCC
AGTACTACCCAAACCTCTTC

Downstream 100 bases:

>100_bases
CTCTAAATATTGGATAGGTTTATGTCTTGGTACATGAATCAAGTATCCGGCCCACTGGAAAAAGGGCTGGATACCCAGGA
CATCAAATCCTGTAGAGATA

Product: hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MNPRELLLDSFHAAVNAADPLKIVPCHLPEPPRGNTLVVGAGKAAAAMARAVEENWPADHPLEGIVVTPYGHGLATNNIM
VIEASHPVPDTQGEMAARAMLESARILTPNDLLLGLFSGGGSSLLSAPIPGVTLDELKSITRQLLRCGAAIQEINIVRKH
LSVVLGGRLAAASRASVHSLIISDVTDNDPSSIASGPCAPDPSTWQDVLALIERYAINIAPQTMGILQKNVNTGSNETPK
LGDPVFRNVKNRIIATARQSLAAAAQFFRAQGITPLILGDTVTGEAKEIAKMHAAIAREVRHYSNPFKPPVALISGGETT
VTVTGSGRGGRNAEFLLSLAIALNGLEEVYALACDTDGIDGNGTNAGAVITPDTLNRVEQADVNPVRLLDDNDAWTFFDQ
LDDLIVTGPTRTNVNDYRVVLVL

Sequences:

>Translated_423_residues
MNPRELLLDSFHAAVNAADPLKIVPCHLPEPPRGNTLVVGAGKAAAAMARAVEENWPADHPLEGIVVTPYGHGLATNNIM
VIEASHPVPDTQGEMAARAMLESARILTPNDLLLGLFSGGGSSLLSAPIPGVTLDELKSITRQLLRCGAAIQEINIVRKH
LSVVLGGRLAAASRASVHSLIISDVTDNDPSSIASGPCAPDPSTWQDVLALIERYAINIAPQTMGILQKNVNTGSNETPK
LGDPVFRNVKNRIIATARQSLAAAAQFFRAQGITPLILGDTVTGEAKEIAKMHAAIAREVRHYSNPFKPPVALISGGETT
VTVTGSGRGGRNAEFLLSLAIALNGLEEVYALACDTDGIDGNGTNAGAVITPDTLNRVEQADVNPVRLLDDNDAWTFFDQ
LDDLIVTGPTRTNVNDYRVVLVL
>Mature_423_residues
MNPRELLLDSFHAAVNAADPLKIVPCHLPEPPRGNTLVVGAGKAAAAMARAVEENWPADHPLEGIVVTPYGHGLATNNIM
VIEASHPVPDTQGEMAARAMLESARILTPNDLLLGLFSGGGSSLLSAPIPGVTLDELKSITRQLLRCGAAIQEINIVRKH
LSVVLGGRLAAASRASVHSLIISDVTDNDPSSIASGPCAPDPSTWQDVLALIERYAINIAPQTMGILQKNVNTGSNETPK
LGDPVFRNVKNRIIATARQSLAAAAQFFRAQGITPLILGDTVTGEAKEIAKMHAAIAREVRHYSNPFKPPVALISGGETT
VTVTGSGRGGRNAEFLLSLAIALNGLEEVYALACDTDGIDGNGTNAGAVITPDTLNRVEQADVNPVRLLDDNDAWTFFDQ
LDDLIVTGPTRTNVNDYRVVLVL

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=449, Percent_Identity=34.2984409799555, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI193205461, Length=430, Percent_Identity=30.6976744186047, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI19920578, Length=445, Percent_Identity=27.6404494382022, Blast_Score=114, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 44698; Mature: 44698

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRELLLDSFHAAVNAADPLKIVPCHLPEPPRGNTLVVGAGKAAAAMARAVEENWPADH
CCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCC
PLEGIVVTPYGHGLATNNIMVIEASHPVPDTQGEMAARAMLESARILTPNDLLLGLFSGG
CCCCEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCC
GSSLLSAPIPGVTLDELKSITRQLLRCGAAIQEINIVRKHLSVVLGGRLAAASRASVHSL
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IISDVTDNDPSSIASGPCAPDPSTWQDVLALIERYAINIAPQTMGILQKNVNTGSNETPK
HEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
LGDPVFRNVKNRIIATARQSLAAAAQFFRAQGITPLILGDTVTGEAKEIAKMHAAIAREV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
RHYSNPFKPPVALISGGETTVTVTGSGRGGRNAEFLLSLAIALNGLEEVYALACDTDGID
HHHCCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCC
GNGTNAGAVITPDTLNRVEQADVNPVRLLDDNDAWTFFDQLDDLIVTGPTRTNVNDYRVV
CCCCCCCEEECCHHHHHHHHCCCCCEEEEECCCCEEHHHHHCCEEEECCCCCCCCCEEEE
LVL
EEC
>Mature Secondary Structure
MNPRELLLDSFHAAVNAADPLKIVPCHLPEPPRGNTLVVGAGKAAAAMARAVEENWPADH
CCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCC
PLEGIVVTPYGHGLATNNIMVIEASHPVPDTQGEMAARAMLESARILTPNDLLLGLFSGG
CCCCEEECCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCC
GSSLLSAPIPGVTLDELKSITRQLLRCGAAIQEINIVRKHLSVVLGGRLAAASRASVHSL
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
IISDVTDNDPSSIASGPCAPDPSTWQDVLALIERYAINIAPQTMGILQKNVNTGSNETPK
HEECCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
LGDPVFRNVKNRIIATARQSLAAAAQFFRAQGITPLILGDTVTGEAKEIAKMHAAIAREV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
RHYSNPFKPPVALISGGETTVTVTGSGRGGRNAEFLLSLAIALNGLEEVYALACDTDGID
HHHCCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCC
GNGTNAGAVITPDTLNRVEQADVNPVRLLDDNDAWTFFDQLDDLIVTGPTRTNVNDYRVV
CCCCCCCEEECCHHHHHHHHCCCCCEEEEECCCCEEHHHHHCCEEEECCCCCCCCCEEEE
LVL
EEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]