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The map label for this gene is flhB [H]

Identifier: 114332395

GI number: 114332395

Start: 2559532

End: 2560662

Strand: Direct

Name: flhB [H]

Synonym: Neut_2443

Alternate gene names: 114332395

Gene position: 2559532-2560662 (Clockwise)

Preceding gene: 114332394

Following gene: 114332396

Centisome position: 96.18

GC content: 54.64

Gene sequence:

>1131_bases
ATGGCAGACGATAACGATCTTGAACGTACTGAACCTGCTTCCCCCAGGCGCCTGGAAAAATCCCGGGAGGAGGGGCAGGT
AGCGCGCTCGCAGGAATTAACCACGTTCACTATGCTGATGGCAGCTTCCGGCAGCTTGTGGGTGATCGGTTCGCTCATTA
TTCAGAAACTGTCCGCCCTGCTGGAAAGCGGCCTGCAAATAGAACGGGAAGTTGCATTCAATCCGGCGCTGTTGTTGCCC
AGGTTATTTCAACTGGCGCTTGATGGGCTATTGGCTATCGCACCCTTACTGGGATGGCTAGTGATTGTGGCGCTGGTATC
GCCCATGCTGTTGAGTGGATGGCTGTTCAGCTCCAAGGCGTTGTTTCCTGACTTCAAACGTCTCAATCCGGTTAATGGAT
TTAAAAGGATATTTTCGTCACACGGCCTGATTGAACTGGTCAAGGCAATCGCCAAGGCTGCAGTCATTGGTGGCGTTGCG
GCCGGGATTATCTGGAGTCACAAACAAGACGTGCTTGATCTGATTGGTATGCCGCTGGACACAGGACTAACCAGCATGGG
CAGACTGATCGGCCTGACCTTTATGCTGATTGTTGGTGCCATGCTGCTGCTCGTCGTAATCGATGTACCTTTCCAGCTCT
GGAATCACGCACGCCAGTTACGGATGTCCAAAGAAGATCTGCGCAAGGAAGCCAAGGAGGATGAAGGTGATCCCCAGGTC
AAGGCGCGCATCCGCAGTATGCAGCGTGAAATGGCACGCCGACGCATGATGGCAGAAGTACCCAGGGCAGATGTCGTGGT
GACCAACCCGACGCACTACGCCGTCGCATTGAAGTATCAGGATCACTCAATGCGTGCACCGAAAGTAGTGGCAAAAGGGT
CGCAACTGATCGCCGCCCGCATTCGTGAATTGGCAGATGAACACCATATTCCGGTGCTGGAAGTGCCGCCGCTGGCACGG
GCACTGTATCACCACGTGGAACTGGATACCGAGATTCCCGAGACGCTCTATACCGCGGTAGCGCATGTGTTGGCCTACGT
TTTCCAGCTGAGAAGATATCAGACGGCGGGTGGTACCGCGCCACAACTATCACCGGAGATAGCGGTGCCAGTGGAACTGG
ATCATGCCTGA

Upstream 100 bases:

>100_bases
TCTCCGGAATTGTTTGATTAACCACCTAAATCGTTGCTTGTTTACGACATCAATTTCAGCGTGAACACGGATAATCCTGG
TTCATCGAGAGGAATCCGCT

Downstream 100 bases:

>100_bases
AACAGATTTACAGGTGAATAAATACCTATTATTGGAATGAATGCTGAATGAATAATATTCTATCTTTAGCAGCTTTGGTA
CGAGACGGCCAAATGCGCAG

Product: flagellar biosynthesis protein FlhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MADDNDLERTEPASPRRLEKSREEGQVARSQELTTFTMLMAASGSLWVIGSLIIQKLSALLESGLQIEREVAFNPALLLP
RLFQLALDGLLAIAPLLGWLVIVALVSPMLLSGWLFSSKALFPDFKRLNPVNGFKRIFSSHGLIELVKAIAKAAVIGGVA
AGIIWSHKQDVLDLIGMPLDTGLTSMGRLIGLTFMLIVGAMLLLVVIDVPFQLWNHARQLRMSKEDLRKEAKEDEGDPQV
KARIRSMQREMARRRMMAEVPRADVVVTNPTHYAVALKYQDHSMRAPKVVAKGSQLIAARIRELADEHHIPVLEVPPLAR
ALYHHVELDTEIPETLYTAVAHVLAYVFQLRRYQTAGGTAPQLSPEIAVPVELDHA

Sequences:

>Translated_376_residues
MADDNDLERTEPASPRRLEKSREEGQVARSQELTTFTMLMAASGSLWVIGSLIIQKLSALLESGLQIEREVAFNPALLLP
RLFQLALDGLLAIAPLLGWLVIVALVSPMLLSGWLFSSKALFPDFKRLNPVNGFKRIFSSHGLIELVKAIAKAAVIGGVA
AGIIWSHKQDVLDLIGMPLDTGLTSMGRLIGLTFMLIVGAMLLLVVIDVPFQLWNHARQLRMSKEDLRKEAKEDEGDPQV
KARIRSMQREMARRRMMAEVPRADVVVTNPTHYAVALKYQDHSMRAPKVVAKGSQLIAARIRELADEHHIPVLEVPPLAR
ALYHHVELDTEIPETLYTAVAHVLAYVFQLRRYQTAGGTAPQLSPEIAVPVELDHA
>Mature_375_residues
ADDNDLERTEPASPRRLEKSREEGQVARSQELTTFTMLMAASGSLWVIGSLIIQKLSALLESGLQIEREVAFNPALLLPR
LFQLALDGLLAIAPLLGWLVIVALVSPMLLSGWLFSSKALFPDFKRLNPVNGFKRIFSSHGLIELVKAIAKAAVIGGVAA
GIIWSHKQDVLDLIGMPLDTGLTSMGRLIGLTFMLIVGAMLLLVVIDVPFQLWNHARQLRMSKEDLRKEAKEDEGDPQVK
ARIRSMQREMARRRMMAEVPRADVVVTNPTHYAVALKYQDHSMRAPKVVAKGSQLIAARIRELADEHHIPVLEVPPLARA
LYHHVELDTEIPETLYTAVAHVLAYVFQLRRYQTAGGTAPQLSPEIAVPVELDHA

Specific function: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1377

COG function: function code NU; Flagellar biosynthesis pathway, component FlhB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=377, Percent_Identity=46.684350132626, Blast_Score=317, Evalue=8e-88,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006136
- InterPro:   IPR006135 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 41679; Mature: 41547

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDNDLERTEPASPRRLEKSREEGQVARSQELTTFTMLMAASGSLWVIGSLIIQKLSAL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LESGLQIEREVAFNPALLLPRLFQLALDGLLAIAPLLGWLVIVALVSPMLLSGWLFSSKA
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LFPDFKRLNPVNGFKRIFSSHGLIELVKAIAKAAVIGGVAAGIIWSHKQDVLDLIGMPLD
CCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TGLTSMGRLIGLTFMLIVGAMLLLVVIDVPFQLWNHARQLRMSKEDLRKEAKEDEGDPQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
KARIRSMQREMARRRMMAEVPRADVVVTNPTHYAVALKYQDHSMRAPKVVAKGSQLIAAR
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHCCHHHHHHH
IRELADEHHIPVLEVPPLARALYHHVELDTEIPETLYTAVAHVLAYVFQLRRYQTAGGTA
HHHHHHHHCCCCEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQLSPEIAVPVELDHA
CCCCCCEEECEECCCC
>Mature Secondary Structure 
ADDNDLERTEPASPRRLEKSREEGQVARSQELTTFTMLMAASGSLWVIGSLIIQKLSAL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LESGLQIEREVAFNPALLLPRLFQLALDGLLAIAPLLGWLVIVALVSPMLLSGWLFSSKA
HHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LFPDFKRLNPVNGFKRIFSSHGLIELVKAIAKAAVIGGVAAGIIWSHKQDVLDLIGMPLD
CCCCHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TGLTSMGRLIGLTFMLIVGAMLLLVVIDVPFQLWNHARQLRMSKEDLRKEAKEDEGDPQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCCHHH
KARIRSMQREMARRRMMAEVPRADVVVTNPTHYAVALKYQDHSMRAPKVVAKGSQLIAAR
HHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCHHHHCCHHHHHHH
IRELADEHHIPVLEVPPLARALYHHVELDTEIPETLYTAVAHVLAYVFQLRRYQTAGGTA
HHHHHHHHCCCCEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PQLSPEIAVPVELDHA
CCCCCCEEECEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002587; 11677609; 3298217 [H]