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The map label for this gene is flhA [H]

Identifier: 114332396

GI number: 114332396

Start: 2560710

End: 2562794

Strand: Direct

Name: flhA [H]

Synonym: Neut_2444

Alternate gene names: 114332396

Gene position: 2560710-2562794 (Clockwise)

Preceding gene: 114332395

Following gene: 114332397

Centisome position: 96.23

GC content: 53.0

Gene sequence:

>2085_bases
ATGAATAATATTCTATCTTTAGCAGCTTTGGTACGAGACGGCCAAATGCGCAGCCTGGCTGGGCCAATGCTGATCATCAT
GATCCTCTCGATGATGGTGCTGCCACTGCCGCCATTCGTCCTGGATGTGCTGTTTACGTTCAACATCGCACTGGCAGTGA
TTGTGCTGCTGGTGAGCCTTTATTCGCGTGATGCACTCGAATTTGCAGTTTTCCCTACTGTTTTGCTGATCACGACACTG
TTACGACTTTCACTCAATGTCGCCTCAACCAGGGTAGTGCTGATGCACGGCCATAACGGCCCGGATGCCGCCGGCAAGGT
TATCGAGGCATTCGGCCATTTTCTGGTGGGTGGAAACTATGCAGTGGGTTTGGTGGTGTTCATTATTCTGATTGTGATCA
ATTTTGTTGTTATTACCAAGGGGGCCGGGCGTATTGCAGAAGTCAGCGCCCGCTTCACCCTGGATGCCATCCCCGGAAAA
CAAATGGCAATTGATGCCGATCTTAATGCCGGGCTGATCCGGGAAGATGAAGCGCGCAAACGGCGCGAACGGGTTGCACA
GGAAGCCAATTTCTACGGCTCAATGGATGGCGCCAGCAAATTCGTGCGGGGCGATGCGATTGCCGGCATTCTGATCATGC
TGATCACCATTATTGGTGGCTTGATCGTGGGCGTGCTGCAACATGATATGAACATGGGTGATGCTGCCAAAAACTACACG
CTGCTGACTATCGGCGACGGTCTGGTCGCACAGATTCCCGCACTCATCATTTCCACTGCCGCTGGTCTGGTGGTCAGCCG
GGTCAGCACCGATGAAGACCTCGGTCAACAATTTGTGAGCCAGCTACTTAACAAGCCACAGGCACTATGGCTGACAGCGG
GTATCCTCGGCGCGCTGGGCCTGGTGCCTGGTATGCCGAATTTTGTTTTTCTGCTGCTGGCTGGAATGATCGGTACGCTT
GCCTATTATGTATCCAGCCGTGCCACTTCGTCGGATGCCAAACTGGAAGAGCCGGAAGTCGTTACCACTGAAACACAGGA
TGCCAGTTGGGAAGATGTGGTTCAGGTTGATACGCTCGGGCTGGAAGTAGGCTATCGTCTCATCCCGCTGGTGGATAAGC
ACCGTCAGGGGGATCTGCTGAAACGCATCAACAGCATCCGCAAGAAATTTGCCCAGGAAATCGGCTTTCTCCCGCCAGTA
GTACATATTCGGGATAACCTGGAATTACGCCCCAATGGCTACCGCATCACCATGAAAGGTTCGGTAATCGGCCAGGGAGA
ATCCTACAACGGCATGCATCTGGCGATTAATCCCGGCGAGGTCACCATGGCGTTGCCGGGTAACCGTACTGAAGATCCGG
CATTCGGGCTGCCCGCTGTCTGGATTGAAACAGAACAACGTGAACTGGCACAAACCAGCGGCTATACCGTAGTTGATGCC
AGCACGGTCGTTACAACACACCTGAATCATCTGATCCGTATGCATGCCTCTGAACTGCTCGGACGGGAAGAATTACAGAA
GTTGCTTGATCATCTGGGGCAAAGAATTCCCAAGCTGACGGATGATCTGATTCCCAAATTGCTGCCACTGGCAACGGTAC
AAAAAATATTGCAACACCTGCTGGAAGAAGGCGTGAATATCCGCGATATGCGCACCATTATTGACACGTTGACCGAACAT
GCTGGGCGCACTCAGGATGTCAGCGAACTGCTGGCGCTGGTGAGAGTAGCGCTGGGCCGGATGATCGTGGAGCAATGTTT
TCCGTCTGATGCCGAAATGCAGGTCATGAGTTTGCACCCCGAACTGGAAAACATCCTGATACAGGTGGTGCAATCCGATC
CAGTGGCAGACGGCGGCATCGAACCTGGCCTGGCCGACACCCTGACACGTGAAGCCAGCAGCTCGGTCAAGCGGCTGGAA
CAGCTCGGATTACCGGTTGTGCTGGTAGTACCGGATGCAATCCGCCTGCTGCTGTCTCGTTTCCTGCGTCGATCGCTGCC
TCAATTAAGGGTGCTGGCTCATTCCGAAATTCCGGATACCAGAAAAATAAAATTCATATCGATCATTGGAGGTAACAAAA
AATGA

Upstream 100 bases:

>100_bases
CGCCACAACTATCACCGGAGATAGCGGTGCCAGTGGAACTGGATCATGCCTGAAACAGATTTACAGGTGAATAAATACCT
ATTATTGGAATGAATGCTGA

Downstream 100 bases:

>100_bases
AAGTAAGAAAATTTCTAGCCGCCACCTCCCATGAGGTGTTACGCAAGGTCAAGGAAGAGCTCGGCGCGGATGCCGTGATT
TTGTCAAACAAACAAGTACC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 694; Mature: 694

Protein sequence:

>694_residues
MNNILSLAALVRDGQMRSLAGPMLIIMILSMMVLPLPPFVLDVLFTFNIALAVIVLLVSLYSRDALEFAVFPTVLLITTL
LRLSLNVASTRVVLMHGHNGPDAAGKVIEAFGHFLVGGNYAVGLVVFIILIVINFVVITKGAGRIAEVSARFTLDAIPGK
QMAIDADLNAGLIREDEARKRRERVAQEANFYGSMDGASKFVRGDAIAGILIMLITIIGGLIVGVLQHDMNMGDAAKNYT
LLTIGDGLVAQIPALIISTAAGLVVSRVSTDEDLGQQFVSQLLNKPQALWLTAGILGALGLVPGMPNFVFLLLAGMIGTL
AYYVSSRATSSDAKLEEPEVVTTETQDASWEDVVQVDTLGLEVGYRLIPLVDKHRQGDLLKRINSIRKKFAQEIGFLPPV
VHIRDNLELRPNGYRITMKGSVIGQGESYNGMHLAINPGEVTMALPGNRTEDPAFGLPAVWIETEQRELAQTSGYTVVDA
STVVTTHLNHLIRMHASELLGREELQKLLDHLGQRIPKLTDDLIPKLLPLATVQKILQHLLEEGVNIRDMRTIIDTLTEH
AGRTQDVSELLALVRVALGRMIVEQCFPSDAEMQVMSLHPELENILIQVVQSDPVADGGIEPGLADTLTREASSSVKRLE
QLGLPVVLVVPDAIRLLLSRFLRRSLPQLRVLAHSEIPDTRKIKFISIIGGNKK

Sequences:

>Translated_694_residues
MNNILSLAALVRDGQMRSLAGPMLIIMILSMMVLPLPPFVLDVLFTFNIALAVIVLLVSLYSRDALEFAVFPTVLLITTL
LRLSLNVASTRVVLMHGHNGPDAAGKVIEAFGHFLVGGNYAVGLVVFIILIVINFVVITKGAGRIAEVSARFTLDAIPGK
QMAIDADLNAGLIREDEARKRRERVAQEANFYGSMDGASKFVRGDAIAGILIMLITIIGGLIVGVLQHDMNMGDAAKNYT
LLTIGDGLVAQIPALIISTAAGLVVSRVSTDEDLGQQFVSQLLNKPQALWLTAGILGALGLVPGMPNFVFLLLAGMIGTL
AYYVSSRATSSDAKLEEPEVVTTETQDASWEDVVQVDTLGLEVGYRLIPLVDKHRQGDLLKRINSIRKKFAQEIGFLPPV
VHIRDNLELRPNGYRITMKGSVIGQGESYNGMHLAINPGEVTMALPGNRTEDPAFGLPAVWIETEQRELAQTSGYTVVDA
STVVTTHLNHLIRMHASELLGREELQKLLDHLGQRIPKLTDDLIPKLLPLATVQKILQHLLEEGVNIRDMRTIIDTLTEH
AGRTQDVSELLALVRVALGRMIVEQCFPSDAEMQVMSLHPELENILIQVVQSDPVADGGIEPGLADTLTREASSSVKRLE
QLGLPVVLVVPDAIRLLLSRFLRRSLPQLRVLAHSEIPDTRKIKFISIIGGNKK
>Mature_694_residues
MNNILSLAALVRDGQMRSLAGPMLIIMILSMMVLPLPPFVLDVLFTFNIALAVIVLLVSLYSRDALEFAVFPTVLLITTL
LRLSLNVASTRVVLMHGHNGPDAAGKVIEAFGHFLVGGNYAVGLVVFIILIVINFVVITKGAGRIAEVSARFTLDAIPGK
QMAIDADLNAGLIREDEARKRRERVAQEANFYGSMDGASKFVRGDAIAGILIMLITIIGGLIVGVLQHDMNMGDAAKNYT
LLTIGDGLVAQIPALIISTAAGLVVSRVSTDEDLGQQFVSQLLNKPQALWLTAGILGALGLVPGMPNFVFLLLAGMIGTL
AYYVSSRATSSDAKLEEPEVVTTETQDASWEDVVQVDTLGLEVGYRLIPLVDKHRQGDLLKRINSIRKKFAQEIGFLPPV
VHIRDNLELRPNGYRITMKGSVIGQGESYNGMHLAINPGEVTMALPGNRTEDPAFGLPAVWIETEQRELAQTSGYTVVDA
STVVTTHLNHLIRMHASELLGREELQKLLDHLGQRIPKLTDDLIPKLLPLATVQKILQHLLEEGVNIRDMRTIIDTLTEH
AGRTQDVSELLALVRVALGRMIVEQCFPSDAEMQVMSLHPELENILIQVVQSDPVADGGIEPGLADTLTREASSSVKRLE
QLGLPVVLVVPDAIRLLLSRFLRRSLPQLRVLAHSEIPDTRKIKFISIIGGNKK

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=691, Percent_Identity=62.5180897250362, Blast_Score=835, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75591; Mature: 75591

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNILSLAALVRDGQMRSLAGPMLIIMILSMMVLPLPPFVLDVLFTFNIALAVIVLLVSL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
YSRDALEFAVFPTVLLITTLLRLSLNVASTRVVLMHGHNGPDAAGKVIEAFGHFLVGGNY
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCH
AVGLVVFIILIVINFVVITKGAGRIAEVSARFTLDAIPGKQMAIDADLNAGLIREDEARK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHHHHH
RRERVAQEANFYGSMDGASKFVRGDAIAGILIMLITIIGGLIVGVLQHDMNMGDAAKNYT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
LLTIGDGLVAQIPALIISTAAGLVVSRVSTDEDLGQQFVSQLLNKPQALWLTAGILGALG
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVPGMPNFVFLLLAGMIGTLAYYVSSRATSSDAKLEEPEVVTTETQDASWEDVVQVDTLG
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
LEVGYRLIPLVDKHRQGDLLKRINSIRKKFAQEIGFLPPVVHIRDNLELRPNGYRITMKG
HHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCCCEEEEEEC
SVIGQGESYNGMHLAINPGEVTMALPGNRTEDPAFGLPAVWIETEQRELAQTSGYTVVDA
CEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHCCCEEEEH
STVVTTHLNHLIRMHASELLGREELQKLLDHLGQRIPKLTDDLIPKLLPLATVQKILQHL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEGVNIRDMRTIIDTLTEHAGRTQDVSELLALVRVALGRMIVEQCFPSDAEMQVMSLHP
HHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCH
ELENILIQVVQSDPVADGGIEPGLADTLTREASSSVKRLEQLGLPVVLVVPDAIRLLLSR
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHH
FLRRSLPQLRVLAHSEIPDTRKIKFISIIGGNKK
HHHHCCHHHHHHHHCCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure
MNNILSLAALVRDGQMRSLAGPMLIIMILSMMVLPLPPFVLDVLFTFNIALAVIVLLVSL
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
YSRDALEFAVFPTVLLITTLLRLSLNVASTRVVLMHGHNGPDAAGKVIEAFGHFLVGGNY
HCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCH
AVGLVVFIILIVINFVVITKGAGRIAEVSARFTLDAIPGKQMAIDADLNAGLIREDEARK
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCHHHHH
RRERVAQEANFYGSMDGASKFVRGDAIAGILIMLITIIGGLIVGVLQHDMNMGDAAKNYT
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
LLTIGDGLVAQIPALIISTAAGLVVSRVSTDEDLGQQFVSQLLNKPQALWLTAGILGALG
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVPGMPNFVFLLLAGMIGTLAYYVSSRATSSDAKLEEPEVVTTETQDASWEDVVQVDTLG
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHH
LEVGYRLIPLVDKHRQGDLLKRINSIRKKFAQEIGFLPPVVHIRDNLELRPNGYRITMKG
HHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEECCCCEEEEEEC
SVIGQGESYNGMHLAINPGEVTMALPGNRTEDPAFGLPAVWIETEQRELAQTSGYTVVDA
CEEECCCCCCCEEEEECCCEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHCCCEEEEH
STVVTTHLNHLIRMHASELLGREELQKLLDHLGQRIPKLTDDLIPKLLPLATVQKILQHL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEEGVNIRDMRTIIDTLTEHAGRTQDVSELLALVRVALGRMIVEQCFPSDAEMQVMSLHP
HHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHCCH
ELENILIQVVQSDPVADGGIEPGLADTLTREASSSVKRLEQLGLPVVLVVPDAIRLLLSR
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHH
FLRRSLPQLRVLAHSEIPDTRKIKFISIIGGNKK
HHHHCCHHHHHHHHCCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]