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The map label for this gene is accA

Identifier: 114332354

GI number: 114332354

Start: 2511682

End: 2512650

Strand: Direct

Name: accA

Synonym: Neut_2398

Alternate gene names: 114332354

Gene position: 2511682-2512650 (Clockwise)

Preceding gene: 114332353

Following gene: 114332355

Centisome position: 94.39

GC content: 45.3

Gene sequence:

>969_bases
ATGAAAAACGTCTTTCTGGACTTTGAAAAAGGCATTGAGGAATTTGAGGCAAAAATAGAGCAATTGCGCTTTGCCCAGGA
TAATTCTGCATTGGACATCTCGGCTGAAATCACTCGCTTACAAGCAAAAAGCCAAGGACTGACCAAAAGTGTTTATGCAA
AACTAACACCTTGGCAGATTTCACAAGTGGCACGTCATCCTCTACGCCCGTCCACGCTTGATTATATAAAACATCTATTT
ACAGATTTTGAAGAATTGCATGGCGATAGAAATTTCGCGGATGATCGGGCTATTGTTGGTGGACTGGCGCACTTTAACGG
TCAGACTGTTATGCTGATTGGGCACCAGAAAGGACACGATACCAAGGAAAAAATCTATCGTAATTTTGGCATGCCCAAGC
CGGAAGGGTATCGCAAAGCACTCCGACTCATGCGTCTTGCAGAAAAATTCTCGATTCCACTGATCACCTTTGTTGATACA
CCAGGCGCCTATCCAGGTATAGATGCCGAAGAGCGTGGGCAATCTGAAGCTATTGGTAAAAATCTTTATGTTATGGCAGG
GCTTAGGATCCCTATTATTTGTATTATTATCGGCGAAGGTGGATCAGGGGGGGCACTGGCTATTGCTGTGGGTGATACCA
GTCTGATGCTGCAATATTCAGTCTATTCAGTAATCTCGCCGGAAGGGTGTGCATCTATTTTATGGAAAAGTGCGGACAAG
GCATCCGATGCAGCTGAGATACTGGGTATTACTGCCGACCGCCTCAAAGAAATGGCCCTAATCGATACCATCATTCCCGA
ACCTGTTGGTGGTGCACACCGTGACTACCCGGCTGTGATGCAATCCGTCAGACAGGCATTGCAAGAATCACTACGGAAAT
TGCAGGATATTCCTTTGGAAACATTACTGCAGAAACGCCTTGATCGGCTGCTTGGATATGGCAGATTCAAAATCAATAAA
CCCGATTAA

Upstream 100 bases:

>100_bases
GGTGTTACATGCCCGCTCGATTCTTTTAGACATCAATGAGTGATACAGGTTAATCCTGTATCATCGCGCTTTTTCACTTC
TTTCAATCTTATCAATCTGC

Downstream 100 bases:

>100_bases
TGATATAACCAGCTGTTTTTTCCATAATCTGAATGCACAAATCAGGCCTGGTGATTGTCTGGTAGTTGCTCTGAGTGGTG
GCGTAGATTCTGTGGTATTG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MKNVFLDFEKGIEEFEAKIEQLRFAQDNSALDISAEITRLQAKSQGLTKSVYAKLTPWQISQVARHPLRPSTLDYIKHLF
TDFEELHGDRNFADDRAIVGGLAHFNGQTVMLIGHQKGHDTKEKIYRNFGMPKPEGYRKALRLMRLAEKFSIPLITFVDT
PGAYPGIDAEERGQSEAIGKNLYVMAGLRIPIICIIIGEGGSGGALAIAVGDTSLMLQYSVYSVISPEGCASILWKSADK
ASDAAEILGITADRLKEMALIDTIIPEPVGGAHRDYPAVMQSVRQALQESLRKLQDIPLETLLQKRLDRLLGYGRFKINK
PD

Sequences:

>Translated_322_residues
MKNVFLDFEKGIEEFEAKIEQLRFAQDNSALDISAEITRLQAKSQGLTKSVYAKLTPWQISQVARHPLRPSTLDYIKHLF
TDFEELHGDRNFADDRAIVGGLAHFNGQTVMLIGHQKGHDTKEKIYRNFGMPKPEGYRKALRLMRLAEKFSIPLITFVDT
PGAYPGIDAEERGQSEAIGKNLYVMAGLRIPIICIIIGEGGSGGALAIAVGDTSLMLQYSVYSVISPEGCASILWKSADK
ASDAAEILGITADRLKEMALIDTIIPEPVGGAHRDYPAVMQSVRQALQESLRKLQDIPLETLLQKRLDRLLGYGRFKINK
PD
>Mature_322_residues
MKNVFLDFEKGIEEFEAKIEQLRFAQDNSALDISAEITRLQAKSQGLTKSVYAKLTPWQISQVARHPLRPSTLDYIKHLF
TDFEELHGDRNFADDRAIVGGLAHFNGQTVMLIGHQKGHDTKEKIYRNFGMPKPEGYRKALRLMRLAEKFSIPLITFVDT
PGAYPGIDAEERGQSEAIGKNLYVMAGLRIPIICIIIGEGGSGGALAIAVGDTSLMLQYSVYSVISPEGCASILWKSADK
ASDAAEILGITADRLKEMALIDTIIPEPVGGAHRDYPAVMQSVRQALQESLRKLQDIPLETLLQKRLDRLLGYGRFKINK
PD

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=313, Percent_Identity=61.0223642172524, Blast_Score=389, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_NITEC (Q0ADH1)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748576.1
- ProteinModelPortal:   Q0ADH1
- SMR:   Q0ADH1
- STRING:   Q0ADH1
- GeneID:   4272530
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2398
- NMPDR:   fig|335283.3.peg.691
- eggNOG:   COG0825
- HOGENOM:   HBG286557
- OMA:   QLTKDIY
- PhylomeDB:   Q0ADH1
- ProtClustDB:   PRK05724
- BioCyc:   NEUT335283:NEUT_2398-MONOMER
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 35756; Mature: 35756

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVFLDFEKGIEEFEAKIEQLRFAQDNSALDISAEITRLQAKSQGLTKSVYAKLTPWQI
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHHHHHHHCCCHHH
SQVARHPLRPSTLDYIKHLFTDFEELHGDRNFADDRAIVGGLAHFNGQTVMLIGHQKGHD
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
TKEKIYRNFGMPKPEGYRKALRLMRLAEKFSIPLITFVDTPGAYPGIDAEERGQSEAIGK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCHHHHCC
NLYVMAGLRIPIICIIIGEGGSGGALAIAVGDTSLMLQYSVYSVISPEGCASILWKSADK
CEEEEECCCEEEEEEEEECCCCCCEEEEEECCCCEEEEHHHHHHCCCCHHHHHHHHCCCC
ASDAAEILGITADRLKEMALIDTIIPEPVGGAHRDYPAVMQSVRQALQESLRKLQDIPLE
CCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
TLLQKRLDRLLGYGRFKINKPD
HHHHHHHHHHHCCCEEEECCCC
>Mature Secondary Structure
MKNVFLDFEKGIEEFEAKIEQLRFAQDNSALDISAEITRLQAKSQGLTKSVYAKLTPWQI
CCCEEEHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCHHHHHHHCCCHHH
SQVARHPLRPSTLDYIKHLFTDFEELHGDRNFADDRAIVGGLAHFNGQTVMLIGHQKGHD
HHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
TKEKIYRNFGMPKPEGYRKALRLMRLAEKFSIPLITFVDTPGAYPGIDAEERGQSEAIGK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCCHHHHCC
NLYVMAGLRIPIICIIIGEGGSGGALAIAVGDTSLMLQYSVYSVISPEGCASILWKSADK
CEEEEECCCEEEEEEEEECCCCCCEEEEEECCCCEEEEHHHHHHCCCCHHHHHHHHCCCC
ASDAAEILGITADRLKEMALIDTIIPEPVGGAHRDYPAVMQSVRQALQESLRKLQDIPLE
CCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
TLLQKRLDRLLGYGRFKINKPD
HHHHHHHHHHHCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA