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The map label for this gene is ihfA

Identifier: 114332285

GI number: 114332285

Start: 2450627

End: 2450935

Strand: Reverse

Name: ihfA

Synonym: Neut_2325

Alternate gene names: 114332285

Gene position: 2450935-2450627 (Counterclockwise)

Preceding gene: 114332286

Following gene: 114332284

Centisome position: 92.1

GC content: 40.45

Gene sequence:

>309_bases
ATGGCTTTAACCAAAGCAGAGCTAACCGATTTATTATTTGAAAATATCGGTCTGAATAAACGTGAAGCAAAAGAAATTGT
CGAGTGTTTTTATGAAGAAATGCGCACAGCGCTCCAAAATGGTGATGGTGTAAAACTTTCAGGCTTTGGCAACTTTCAAT
TGAGGACTAAACCACAACGGCCGGGGCGGAATCCCAAAACTGGTGAAGAAATTCCCATTTCAGCACGAAGAGTGGTTACT
TTTCATGCAAGCCAGAAGCTTAAATCTATGGTAGAAGCTAACTATCGTGGGGAACCAAACGTAAATTAA

Upstream 100 bases:

>100_bases
TCTTCACTCTTTCACTTGGTGCGTTATGATTGCTCAAATCCGGCAAATCCTGGTGTTAGTTCAAGACATTTACTCTGTTT
TCTAACTTAAGGGTGGATAT

Downstream 100 bases:

>100_bases
CATTCCGTTTTTTTATATTGATAAATATATATTGTTTTGAGTGGTAAATAAGATAAATGTGTATAGCAAATCAGGATACA
TATTCTGTATAACCGGAGTA

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MALTKAELTDLLFENIGLNKREAKEIVECFYEEMRTALQNGDGVKLSGFGNFQLRTKPQRPGRNPKTGEEIPISARRVVT
FHASQKLKSMVEANYRGEPNVN

Sequences:

>Translated_102_residues
MALTKAELTDLLFENIGLNKREAKEIVECFYEEMRTALQNGDGVKLSGFGNFQLRTKPQRPGRNPKTGEEIPISARRVVT
FHASQKLKSMVEANYRGEPNVN
>Mature_101_residues
ALTKAELTDLLFENIGLNKREAKEIVECFYEEMRTALQNGDGVKLSGFGNFQLRTKPQRPGRNPKTGEEIPISARRVVTF
HASQKLKSMVEANYRGEPNVN

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=71.7391304347826, Blast_Score=139, Evalue=5e-35,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=37.7777777777778, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=34.8314606741573, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_NITEC (Q0ADP0)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748507.1
- ProteinModelPortal:   Q0ADP0
- SMR:   Q0ADP0
- STRING:   Q0ADP0
- GeneID:   4272391
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2325
- NMPDR:   fig|335283.3.peg.86
- eggNOG:   COG0776
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- PhylomeDB:   Q0ADP0
- ProtClustDB:   PRK00285
- BioCyc:   NEUT335283:NEUT_2325-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11525; Mature: 11394

Theoretical pI: Translated: 9.68; Mature: 9.68

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTKAELTDLLFENIGLNKREAKEIVECFYEEMRTALQNGDGVKLSGFGNFQLRTKPQR
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCC
PGRNPKTGEEIPISARRVVTFHASQKLKSMVEANYRGEPNVN
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALTKAELTDLLFENIGLNKREAKEIVECFYEEMRTALQNGDGVKLSGFGNFQLRTKPQR
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCCC
PGRNPKTGEEIPISARRVVTFHASQKLKSMVEANYRGEPNVN
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA