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The map label for this gene is pheT [H]

Identifier: 114332286

GI number: 114332286

Start: 2451148

End: 2453526

Strand: Reverse

Name: pheT [H]

Synonym: Neut_2326

Alternate gene names: 114332286

Gene position: 2453526-2451148 (Counterclockwise)

Preceding gene: 114332287

Following gene: 114332285

Centisome position: 92.2

GC content: 44.35

Gene sequence:

>2379_bases
ATGAAATTTCCCGGGAACTGGCTACGTAAATTGGTTGACTACCAATGCTCTGATGAAGAGCTGGCACACAAGTTGACTAT
GGCTGGATTAGAAGTTGAGAGTGTGGTGCCGGTTGCTCCTTTTTTTGACAAAGTGGTCATCGCAGAGGTGATGTCTGTTC
AAAAACATGCAAATGCCGATCGGCTAAGAGTATGTAAGGTGGATGTGGGAAACTATTCTGATGAACCTTTACAAATCGTT
TGTGGGGCACAGAATGTTACAGAAGGAATGAAGACCGTATGTGCCTTGATAGGTGCACGGCTGCCAGAATTGAATATACG
GCAAGGTAAGATACGCGGTGTGGAATCTTTTGGCATGTTGTGTTCTGCAAGAGAACTCGGGTTGGTAAGTGAGGCTGACG
GACTTATTGAACTTCCAGATGATGCGCCTGCAGGTATCAGCTTTAGAGAATATGACGGGTTGGATGATAGTATTTTTACC
CTGAAATTGACGCCTAATCGAGCTGATTGCTTGGGGATGTTCGGTATTGCTCGCGAGGTCGCTGCTATTACTGCCGGCAA
ACTCAATTTGCCAGAAATTAAACCTGTTAATCCTGAAATTGCAGATGTTCTGCGAATCCGGGTTGAAGAGCCTCAATCCT
GCCCGCTTTACTGTGGTCGTATCGTCAAAGGTATCATCACCAGCACACAAACTCCTCTGTGGATGAATCAGTATTTGGTG
CGGGCTGGTTTGCGTCTGATTAATCCGGTGGTTGATATTATTAACTATGTCATGCTGGAAACAGGTCAGCCGATGCATGC
TTTTGATCTTGCTAAGATTGAAAAAGGGGCAGAACAGGAGATCCGTGTGCGCTATGCCGTTGCAAATGAACGCTTACGAC
TGTTAAACGGTGAATGCCTTGATTTGCAAGAAGATCTGTTAGTCATAGCTGATAGTAGCAAACCTTTGGCATTGGCTGGC
ATCATGGGTGGCAGTGAAAGTGAGGTAGAGGGAGGCACAACGGATATTTTTATCGAGAGTGCTTTTTTTTCGCCGGCTGC
GATTAGTGGCAAGTCATTTAAATTGGGTTTTAGCTCGGATTCCTCGCATCGATTCGAACGAGGGGTGGATTTCTCCATGA
CGCGTAATGCACTTGAGCGTGCCACTGCGCTGGTTTTGGATATATGTGGGGGGAAAATAGGCCCAGTAGTAGAGGTTAGT
AACGATTTGCCGCGACGAGATGCGGTCGAGGTTCGTCAAAAGCGCATAGCAAAGATCCTGGGAGTGGATTTTGGGATTGA
ACTGATATCAGAATATTTCCGGAGATTACAATTTGGTCACTCTGTTAGCGGCGATACGTTTTATGTAGTGCCACCTGCAT
CGCGCTTTGATTTAGTCATCGAAGAAGATTTTATTGAAGAGCTTGCGCGTATGCATGGATATGACCTGATTCCCGCGCAG
TTGCCCAAGGCATCGGCACATATGCTAACGGAACCAGAAATTGGTATTGCGCCTGTTAAGCGATTGCGTCAAATTCTGGT
GGCAAGGGATTATCAGGAGGTTATTAATTACACATTTGTAGACACTCAGTGGGAAGCAGATCTTTGCGGAAATAACTTAC
CGGTAAAACTGAAGAATCCAATTGCAAGTCATATGGATGTTATGCGTAGCAGCCTTTTTGGCGGATTGATCAACAATCTA
CAATTTAATCTGAATCGCAAGCAAAGTAGGGTTAGGATTTTTGAGATAGGTTCCTGTTTCAGCAAGGATAATGATGAAGA
AAAAGAGGTAGAGAATCTGGCCGTTCTTTGTTCAGGGAATGTGCATCCGGAGCAATGGGGTGTTACGGATCGGGATGTTG
ATTTTTATGACGTCAAAATGGATGTTGAGTCCTTATTCTGGCCAAGAAATATTGATTTCGAGTCGGCTGTTCATCCGGCA
TTACATCCAGGAAAATCAGCCAGAATTCTGATTGACAAGAGTCCGATTGGCTGGATAGGAGAACTTCATCCTCGTTGGCA
GAGAAAATATCATTTATCACAATCTGCGATCCTATTTGAATTGCAAATAGAAGCTCTTGCTAGTGACTTGCTGCCGATGA
TGCAAGTACTCTCAAAATTTCCACCAGTAAGGCGTGATATTGCGGTGGTGGTAGAGAATGAGGTAAGTATGGCCAAGTTA
CTGGAAGCAATGAACTCAGAAAAAGATAAAAGCGTCAGTGAGATATCTTTATTTGATTTATATAGTGGTGAAAATTTAGA
GCAAGGGAAGAAGAGCCTTGCTTTCCGTATTTTGTTGCAAGGTACTGAAAAAAACCTTACAGATCAGGAAATCGATCAAG
CAGTAAATGGGCTGATCAATGTTCTCGGTCGAAAGTTTGGTGCAACACTACGCGGCTAG

Upstream 100 bases:

>100_bases
TTTAACTATGTTGCGTTATGGAGTTAATGATCTGCGTCTATTCTTTGAAAATGACTTACGTTTTCTGAAACAATTTAATT
GATGCTCTAGACTTGTAGTT

Downstream 100 bases:

>100_bases
TTGGGAGTTCTGTCCGCTGAGACTGGCCGGCTGAATTGGTGGGAAGAACGTTTTTTTTCCTGAGTTCTTCGCGGTATAGA
TTTGTCGTGTATTTCGAAAT

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS [H]

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MKFPGNWLRKLVDYQCSDEELAHKLTMAGLEVESVVPVAPFFDKVVIAEVMSVQKHANADRLRVCKVDVGNYSDEPLQIV
CGAQNVTEGMKTVCALIGARLPELNIRQGKIRGVESFGMLCSARELGLVSEADGLIELPDDAPAGISFREYDGLDDSIFT
LKLTPNRADCLGMFGIAREVAAITAGKLNLPEIKPVNPEIADVLRIRVEEPQSCPLYCGRIVKGIITSTQTPLWMNQYLV
RAGLRLINPVVDIINYVMLETGQPMHAFDLAKIEKGAEQEIRVRYAVANERLRLLNGECLDLQEDLLVIADSSKPLALAG
IMGGSESEVEGGTTDIFIESAFFSPAAISGKSFKLGFSSDSSHRFERGVDFSMTRNALERATALVLDICGGKIGPVVEVS
NDLPRRDAVEVRQKRIAKILGVDFGIELISEYFRRLQFGHSVSGDTFYVVPPASRFDLVIEEDFIEELARMHGYDLIPAQ
LPKASAHMLTEPEIGIAPVKRLRQILVARDYQEVINYTFVDTQWEADLCGNNLPVKLKNPIASHMDVMRSSLFGGLINNL
QFNLNRKQSRVRIFEIGSCFSKDNDEEKEVENLAVLCSGNVHPEQWGVTDRDVDFYDVKMDVESLFWPRNIDFESAVHPA
LHPGKSARILIDKSPIGWIGELHPRWQRKYHLSQSAILFELQIEALASDLLPMMQVLSKFPPVRRDIAVVVENEVSMAKL
LEAMNSEKDKSVSEISLFDLYSGENLEQGKKSLAFRILLQGTEKNLTDQEIDQAVNGLINVLGRKFGATLRG

Sequences:

>Translated_792_residues
MKFPGNWLRKLVDYQCSDEELAHKLTMAGLEVESVVPVAPFFDKVVIAEVMSVQKHANADRLRVCKVDVGNYSDEPLQIV
CGAQNVTEGMKTVCALIGARLPELNIRQGKIRGVESFGMLCSARELGLVSEADGLIELPDDAPAGISFREYDGLDDSIFT
LKLTPNRADCLGMFGIAREVAAITAGKLNLPEIKPVNPEIADVLRIRVEEPQSCPLYCGRIVKGIITSTQTPLWMNQYLV
RAGLRLINPVVDIINYVMLETGQPMHAFDLAKIEKGAEQEIRVRYAVANERLRLLNGECLDLQEDLLVIADSSKPLALAG
IMGGSESEVEGGTTDIFIESAFFSPAAISGKSFKLGFSSDSSHRFERGVDFSMTRNALERATALVLDICGGKIGPVVEVS
NDLPRRDAVEVRQKRIAKILGVDFGIELISEYFRRLQFGHSVSGDTFYVVPPASRFDLVIEEDFIEELARMHGYDLIPAQ
LPKASAHMLTEPEIGIAPVKRLRQILVARDYQEVINYTFVDTQWEADLCGNNLPVKLKNPIASHMDVMRSSLFGGLINNL
QFNLNRKQSRVRIFEIGSCFSKDNDEEKEVENLAVLCSGNVHPEQWGVTDRDVDFYDVKMDVESLFWPRNIDFESAVHPA
LHPGKSARILIDKSPIGWIGELHPRWQRKYHLSQSAILFELQIEALASDLLPMMQVLSKFPPVRRDIAVVVENEVSMAKL
LEAMNSEKDKSVSEISLFDLYSGENLEQGKKSLAFRILLQGTEKNLTDQEIDQAVNGLINVLGRKFGATLRG
>Mature_792_residues
MKFPGNWLRKLVDYQCSDEELAHKLTMAGLEVESVVPVAPFFDKVVIAEVMSVQKHANADRLRVCKVDVGNYSDEPLQIV
CGAQNVTEGMKTVCALIGARLPELNIRQGKIRGVESFGMLCSARELGLVSEADGLIELPDDAPAGISFREYDGLDDSIFT
LKLTPNRADCLGMFGIAREVAAITAGKLNLPEIKPVNPEIADVLRIRVEEPQSCPLYCGRIVKGIITSTQTPLWMNQYLV
RAGLRLINPVVDIINYVMLETGQPMHAFDLAKIEKGAEQEIRVRYAVANERLRLLNGECLDLQEDLLVIADSSKPLALAG
IMGGSESEVEGGTTDIFIESAFFSPAAISGKSFKLGFSSDSSHRFERGVDFSMTRNALERATALVLDICGGKIGPVVEVS
NDLPRRDAVEVRQKRIAKILGVDFGIELISEYFRRLQFGHSVSGDTFYVVPPASRFDLVIEEDFIEELARMHGYDLIPAQ
LPKASAHMLTEPEIGIAPVKRLRQILVARDYQEVINYTFVDTQWEADLCGNNLPVKLKNPIASHMDVMRSSLFGGLINNL
QFNLNRKQSRVRIFEIGSCFSKDNDEEKEVENLAVLCSGNVHPEQWGVTDRDVDFYDVKMDVESLFWPRNIDFESAVHPA
LHPGKSARILIDKSPIGWIGELHPRWQRKYHLSQSAILFELQIEALASDLLPMMQVLSKFPPVRRDIAVVVENEVSMAKL
LEAMNSEKDKSVSEISLFDLYSGENLEQGKKSLAFRILLQGTEKNLTDQEIDQAVNGLINVLGRKFGATLRG

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI124028525, Length=401, Percent_Identity=23.4413965087282, Blast_Score=72, Evalue=3e-12,
Organism=Escherichia coli, GI1788006, Length=801, Percent_Identity=43.1960049937578, Blast_Score=620, Evalue=1e-179,
Organism=Drosophila melanogaster, GI21355211, Length=398, Percent_Identity=23.6180904522613, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547 [H]

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 88135; Mature: 88135

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFPGNWLRKLVDYQCSDEELAHKLTMAGLEVESVVPVAPFFDKVVIAEVMSVQKHANAD
CCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
RLRVCKVDVGNYSDEPLQIVCGAQNVTEGMKTVCALIGARLPELNIRQGKIRGVESFGML
CEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
CSARELGLVSEADGLIELPDDAPAGISFREYDGLDDSIFTLKLTPNRADCLGMFGIAREV
HHHHHCCCEECCCCCEECCCCCCCCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
AAITAGKLNLPEIKPVNPEIADVLRIRVEEPQSCPLYCGRIVKGIITSTQTPLWMNQYLV
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
RAGLRLINPVVDIINYVMLETGQPMHAFDLAKIEKGAEQEIRVRYAVANERLRLLNGECL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEEEEEEHHCHHHHHCCCCC
DLQEDLLVIADSSKPLALAGIMGGSESEVEGGTTDIFIESAFFSPAAISGKSFKLGFSSD
CCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCC
SSHRFERGVDFSMTRNALERATALVLDICGGKIGPVVEVSNDLPRRDAVEVRQKRIAKIL
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
GVDFGIELISEYFRRLQFGHSVSGDTFYVVPPASRFDLVIEEDFIEELARMHGYDLIPAQ
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHCCCCCCCCC
LPKASAHMLTEPEIGIAPVKRLRQILVARDYQEVINYTFVDTQWEADLCGNNLPVKLKNP
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHCCCCCCEEECCH
IASHMDVMRSSLFGGLINNLQFNLNRKQSRVRIFEIGSCFSKDNDEEKEVENLAVLCSGN
HHHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEEEECCHHCCCCCHHHHHHHEEEEECCC
VHPEQWGVTDRDVDFYDVKMDVESLFWPRNIDFESAVHPALHPGKSARILIDKSPIGWIG
CCHHHCCCCCCCCCEEEEEECHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCCCCC
ELHPRWQRKYHLSQSAILFELQIEALASDLLPMMQVLSKFPPVRRDIAVVVENEVSMAKL
CCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHH
LEAMNSEKDKSVSEISLFDLYSGENLEQGKKSLAFRILLQGTEKNLTDQEIDQAVNGLIN
HHHHCCCCCCCHHHEEEEEECCCCCHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHH
VLGRKFGATLRG
HHHHHHCCCCCC
>Mature Secondary Structure
MKFPGNWLRKLVDYQCSDEELAHKLTMAGLEVESVVPVAPFFDKVVIAEVMSVQKHANAD
CCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHCCCC
RLRVCKVDVGNYSDEPLQIVCGAQNVTEGMKTVCALIGARLPELNIRQGKIRGVESFGML
CEEEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
CSARELGLVSEADGLIELPDDAPAGISFREYDGLDDSIFTLKLTPNRADCLGMFGIAREV
HHHHHCCCEECCCCCEECCCCCCCCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHH
AAITAGKLNLPEIKPVNPEIADVLRIRVEEPQSCPLYCGRIVKGIITSTQTPLWMNQYLV
HHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
RAGLRLINPVVDIINYVMLETGQPMHAFDLAKIEKGAEQEIRVRYAVANERLRLLNGECL
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHEEEEEEEHHCHHHHHCCCCC
DLQEDLLVIADSSKPLALAGIMGGSESEVEGGTTDIFIESAFFSPAAISGKSFKLGFSSD
CCCCCEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCC
SSHRFERGVDFSMTRNALERATALVLDICGGKIGPVVEVSNDLPRRDAVEVRQKRIAKIL
CCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHH
GVDFGIELISEYFRRLQFGHSVSGDTFYVVPPASRFDLVIEEDFIEELARMHGYDLIPAQ
CCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEECHHHHHHHHHHCCCCCCCCC
LPKASAHMLTEPEIGIAPVKRLRQILVARDYQEVINYTFVDTQWEADLCGNNLPVKLKNP
CCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHCCCCCCEEECCH
IASHMDVMRSSLFGGLINNLQFNLNRKQSRVRIFEIGSCFSKDNDEEKEVENLAVLCSGN
HHHHHHHHHHHHHHHHHHCCEECCCCCCCCEEEEEECCHHCCCCCHHHHHHHEEEEECCC
VHPEQWGVTDRDVDFYDVKMDVESLFWPRNIDFESAVHPALHPGKSARILIDKSPIGWIG
CCHHHCCCCCCCCCEEEEEECHHHHCCCCCCCHHHCCCCCCCCCCCEEEEEECCCCCCCC
ELHPRWQRKYHLSQSAILFELQIEALASDLLPMMQVLSKFPPVRRDIAVVVENEVSMAKL
CCCHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHH
LEAMNSEKDKSVSEISLFDLYSGENLEQGKKSLAFRILLQGTEKNLTDQEIDQAVNGLIN
HHHHCCCCCCCHHHEEEEEECCCCCHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHH
VLGRKFGATLRG
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]