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The map label for this gene is nadA [H]

Identifier: 114332259

GI number: 114332259

Start: 2424695

End: 2425795

Strand: Reverse

Name: nadA [H]

Synonym: Neut_2299

Alternate gene names: 114332259

Gene position: 2425795-2424695 (Counterclockwise)

Preceding gene: 114332268

Following gene: 114332258

Centisome position: 91.16

GC content: 48.59

Gene sequence:

>1101_bases
ATGCAAGCAAACGCAATCGATTTTGAGAATTACGAATTACTGCAAGATGAAGTATGTACGCAACGGATCGTTGCAGCTAA
ACAGAAGCTGGGAAAGCGCGCTATTATATTGGCACATCACTATCAGCGTGCAGATGTTTACCGGCATGCCGATCTGACCG
GAGACTCACTTAAGCTTTCTTATCTCGCCGCGCAGACAGATGCTGATTTTCTGGTGTTTTGCGGGGTGCACTTCATGGCA
GAGGTAGCGGATATTCTTTCCAGCCCTGAACAAACCGTCATCCTGCCTGATCTTTCCGCAGGTTGCTCTATGGCAGATAT
GGCTAATCTCACCAAGGTAGAACGTGCTTGGCGTGAACTGACAGAAGTGCTCGACCCGGATGAGGGGGTGACACCAGTAA
CTTATATCAATTCCAGTGCTGATCTAAAGGCCTTTTGTGGGCAACATGGTGGTATCGTTTGTACTTCCAGTAACGCTGTA
AAGATTCTGCAATGGGCATTTGACCGACGTGAAAAAGTACTGTTTTTCCCTGATCAGCACCTAGGTCGTTGGAGCGGATA
CAAGATGGGGCTATCGTCGGATGAAATGCCAGTATGGGATTTTGATGAACCCATGGGCGGATTGACACCAGAACAGATTG
AAAAAGCCAAAATCCTTTTATGGAAAGGGCATTGTTCCGTTCACCAAATGTTTCAGCCGCAGCATATCCTTCGCTTTCGC
AACCAATATCCGGATGGGTTGGTTATTTCACATCCGGAATGCAGCTTTGAGGTGTGTAAGGCATCTGATTTTGTTGGATC
GACCGAGTACATCATCAATACCATCCGGGCAGCGAAAGCTGGTACTCGCTGGCTGGTCGGGACGGAATTGAATCTGGTTG
GTCGCATTGCCGAGGAGTTCAAGTCCGAAGGCAAAATTATTCAGTTCATGTCGCCGATGGTATGTATGTGTTCGACTATG
GCGAGGATCGATCCACAGCACTTGGCCTGGTCACTTGAAAATCTGGCTGAGGGTCGTGTGGTTAATCAGATTAGCGTGCC
GGAACCACAGGCCAGTCTGGCCAGGCTGACGCTCGAAAAGATGCTTGAGGTCTCGAAATAG

Upstream 100 bases:

>100_bases
CAGAATCTGCAGAACAGCTTTTTAATTTGCACTTTTTGCTTGAATAAGTATCTTAATGTGATTATGGTCATATTTCACGA
TAAATAAAGCTGGATTGATT

Downstream 100 bases:

>100_bases
TATCGATGGTGAAATTGCCGGTTTTGTCTGCGGATACTGACAGGATTGCTTCTCTGCCAGGAAACGAAGCAATGCGTGAA
TCTAATCGGACATTACATAT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MQANAIDFENYELLQDEVCTQRIVAAKQKLGKRAIILAHHYQRADVYRHADLTGDSLKLSYLAAQTDADFLVFCGVHFMA
EVADILSSPEQTVILPDLSAGCSMADMANLTKVERAWRELTEVLDPDEGVTPVTYINSSADLKAFCGQHGGIVCTSSNAV
KILQWAFDRREKVLFFPDQHLGRWSGYKMGLSSDEMPVWDFDEPMGGLTPEQIEKAKILLWKGHCSVHQMFQPQHILRFR
NQYPDGLVISHPECSFEVCKASDFVGSTEYIINTIRAAKAGTRWLVGTELNLVGRIAEEFKSEGKIIQFMSPMVCMCSTM
ARIDPQHLAWSLENLAEGRVVNQISVPEPQASLARLTLEKMLEVSK

Sequences:

>Translated_366_residues
MQANAIDFENYELLQDEVCTQRIVAAKQKLGKRAIILAHHYQRADVYRHADLTGDSLKLSYLAAQTDADFLVFCGVHFMA
EVADILSSPEQTVILPDLSAGCSMADMANLTKVERAWRELTEVLDPDEGVTPVTYINSSADLKAFCGQHGGIVCTSSNAV
KILQWAFDRREKVLFFPDQHLGRWSGYKMGLSSDEMPVWDFDEPMGGLTPEQIEKAKILLWKGHCSVHQMFQPQHILRFR
NQYPDGLVISHPECSFEVCKASDFVGSTEYIINTIRAAKAGTRWLVGTELNLVGRIAEEFKSEGKIIQFMSPMVCMCSTM
ARIDPQHLAWSLENLAEGRVVNQISVPEPQASLARLTLEKMLEVSK
>Mature_366_residues
MQANAIDFENYELLQDEVCTQRIVAAKQKLGKRAIILAHHYQRADVYRHADLTGDSLKLSYLAAQTDADFLVFCGVHFMA
EVADILSSPEQTVILPDLSAGCSMADMANLTKVERAWRELTEVLDPDEGVTPVTYINSSADLKAFCGQHGGIVCTSSNAV
KILQWAFDRREKVLFFPDQHLGRWSGYKMGLSSDEMPVWDFDEPMGGLTPEQIEKAKILLWKGHCSVHQMFQPQHILRFR
NQYPDGLVISHPECSFEVCKASDFVGSTEYIINTIRAAKAGTRWLVGTELNLVGRIAEEFKSEGKIIQFMSPMVCMCSTM
ARIDPQHLAWSLENLAEGRVVNQISVPEPQASLARLTLEKMLEVSK

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 3 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=245, Percent_Identity=32.6530612244898, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41031; Mature: 41031

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQANAIDFENYELLQDEVCTQRIVAAKQKLGKRAIILAHHYQRADVYRHADLTGDSLKLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCCCEEEE
YLAAQTDADFLVFCGVHFMAEVADILSSPEQTVILPDLSAGCSMADMANLTKVERAWREL
EEEECCCCCEEEHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
TEVLDPDEGVTPVTYINSSADLKAFCGQHGGIVCTSSNAVKILQWAFDRREKVLFFPDQH
HHHHCCCCCCCCEEEECCCCCHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCHH
LGRWSGYKMGLSSDEMPVWDFDEPMGGLTPEQIEKAKILLWKGHCSVHQMFQPQHILRFR
CCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCHHHHCCHHHHHHHH
NQYPDGLVISHPECSFEVCKASDFVGSTEYIINTIRAAKAGTRWLVGTELNLVGRIAEEF
HCCCCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
KSEGKIIQFMSPMVCMCSTMARIDPQHLAWSLENLAEGRVVNQISVPEPQASLARLTLEK
HHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
MLEVSK
HHHCCC
>Mature Secondary Structure
MQANAIDFENYELLQDEVCTQRIVAAKQKLGKRAIILAHHYQRADVYRHADLTGDSLKLS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCCCCCEEEE
YLAAQTDADFLVFCGVHFMAEVADILSSPEQTVILPDLSAGCSMADMANLTKVERAWREL
EEEECCCCCEEEHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
TEVLDPDEGVTPVTYINSSADLKAFCGQHGGIVCTSSNAVKILQWAFDRREKVLFFPDQH
HHHHCCCCCCCCEEEECCCCCHHHHHCCCCCEEEECCCCHHHHHHHHCCCCEEEECCCHH
LGRWSGYKMGLSSDEMPVWDFDEPMGGLTPEQIEKAKILLWKGHCSVHQMFQPQHILRFR
CCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCHHHHCCHHHHHHHH
NQYPDGLVISHPECSFEVCKASDFVGSTEYIINTIRAAKAGTRWLVGTELNLVGRIAEEF
HCCCCCEEEECCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHH
KSEGKIIQFMSPMVCMCSTMARIDPQHLAWSLENLAEGRVVNQISVPEPQASLARLTLEK
HHCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHH
MLEVSK
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA