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The map label for this gene is orn

Identifier: 114332250

GI number: 114332250

Start: 2415186

End: 2415731

Strand: Direct

Name: orn

Synonym: Neut_2290

Alternate gene names: 114332250

Gene position: 2415186-2415731 (Clockwise)

Preceding gene: 114332246

Following gene: 114332251

Centisome position: 90.76

GC content: 47.62

Gene sequence:

>546_bases
ATGGCACAAGACAGTAACAACCTTATCTGGATAGACATGGAAATGACCGGTCTGAATCCGAATACTGACTGCATTATCGA
AATCGCCCTGGTCGTCACAGACGCGCAACTCAACACAGTAGCTGAAGCACCGGTACTGGTCATTTCACAGCCAGACAGTG
TCCTTAACGGGATGGATAAATGGAACCAGTCCACACACGGCAAATCTGGCCTGATCGATAAGGTCAAGGCTTCAACATTG
AGTGAAGCCGAAGCAGAAGCTCGCATGCTGGCATTTTTGGCGCCATACGTCCCGGCCGATATCTCGCCTATGTGCGGAAA
TTCAATCTGCCAGGATCGACGTTTTCTAGCCAGATGCATGCCGCAACTGGAAGCTTATTTTCATTACCGCAATCTGGATG
TCAGTACACTCAAGGAATTGGCCAAACGCTGGAAACCTGAAGTTGCCCAGGGATTCAACAAACAAGGTAAACATGAAGCA
CTGGCTGATATTTACGACTCAATAGAAGAACTCAAACACTATCGCCAGCACCTGTTTAATATCTGA

Upstream 100 bases:

>100_bases
GTCCCCCCCCGGAAAACAGAGGAGCAGACCGATCACGACGAGTATACTTGGATGTGACACAATCCTATCTTGAAAATTCA
CGTAACAAACATTCAGAATT

Downstream 100 bases:

>100_bases
ATGTCCGTGATTCATCTACTACAGGAGCTCAATGAATGACTCAACGCACTGCATTTACACTTACCATCAGCCCCAAAATA
CCGGCACGCTTGGATCGGTT

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAQDSNNLIWIDMEMTGLNPNTDCIIEIALVVTDAQLNTVAEAPVLVISQPDSVLNGMDKWNQSTHGKSGLIDKVKASTL
SEAEAEARMLAFLAPYVPADISPMCGNSICQDRRFLARCMPQLEAYFHYRNLDVSTLKELAKRWKPEVAQGFNKQGKHEA
LADIYDSIEELKHYRQHLFNI

Sequences:

>Translated_181_residues
MAQDSNNLIWIDMEMTGLNPNTDCIIEIALVVTDAQLNTVAEAPVLVISQPDSVLNGMDKWNQSTHGKSGLIDKVKASTL
SEAEAEARMLAFLAPYVPADISPMCGNSICQDRRFLARCMPQLEAYFHYRNLDVSTLKELAKRWKPEVAQGFNKQGKHEA
LADIYDSIEELKHYRQHLFNI
>Mature_180_residues
AQDSNNLIWIDMEMTGLNPNTDCIIEIALVVTDAQLNTVAEAPVLVISQPDSVLNGMDKWNQSTHGKSGLIDKVKASTLS
EAEAEARMLAFLAPYVPADISPMCGNSICQDRRFLARCMPQLEAYFHYRNLDVSTLKELAKRWKPEVAQGFNKQGKHEAL
ADIYDSIEELKHYRQHLFNI

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=176, Percent_Identity=44.8863636363636, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=59.6685082872928, Blast_Score=234, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17557752, Length=172, Percent_Identity=45.9302325581395, Blast_Score=159, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6323088, Length=176, Percent_Identity=37.5, Blast_Score=110, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21355135, Length=174, Percent_Identity=41.9540229885057, Blast_Score=156, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_NITEC (Q0ADS5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748472.1
- ProteinModelPortal:   Q0ADS5
- SMR:   Q0ADS5
- STRING:   Q0ADS5
- GeneID:   4274313
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2290
- NMPDR:   fig|335283.3.peg.33
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- PhylomeDB:   Q0ADS5
- ProtClustDB:   PRK05359
- BioCyc:   NEUT335283:NEUT_2290-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20366; Mature: 20235

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQDSNNLIWIDMEMTGLNPNTDCIIEIALVVTDAQLNTVAEAPVLVISQPDSVLNGMDK
CCCCCCCEEEEEEEEECCCCCCHHEEEEEHHEECCHHHHHCCCCEEEEECCHHHHHHHHH
WNQSTHGKSGLIDKVKASTLSEAEAEARMLAFLAPYVPADISPMCGNSICQDRRFLARCM
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
PQLEAYFHYRNLDVSTLKELAKRWKPEVAQGFNKQGKHEALADIYDSIEELKHYRQHLFN
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
I
C
>Mature Secondary Structure 
AQDSNNLIWIDMEMTGLNPNTDCIIEIALVVTDAQLNTVAEAPVLVISQPDSVLNGMDK
CCCCCCEEEEEEEEECCCCCCHHEEEEEHHEECCHHHHHCCCCEEEEECCHHHHHHHHH
WNQSTHGKSGLIDKVKASTLSEAEAEARMLAFLAPYVPADISPMCGNSICQDRRFLARCM
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
PQLEAYFHYRNLDVSTLKELAKRWKPEVAQGFNKQGKHEALADIYDSIEELKHYRQHLFN
HHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
I
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA