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The map label for this gene is engA

Identifier: 114332129

GI number: 114332129

Start: 2293323

End: 2294729

Strand: Reverse

Name: engA

Synonym: Neut_2164

Alternate gene names: 114332129

Gene position: 2294729-2293323 (Counterclockwise)

Preceding gene: 114332130

Following gene: 114332128

Centisome position: 86.23

GC content: 50.46

Gene sequence:

>1407_bases
ATGAAACCCACTCTCGTACTGGTTGGGCGTCCGAATGTCGGAAAATCGACATTATTCAACCGTCTGACTCGCAGTCGTGA
TGCGATTGTGGCAGATATTCCCGGATTGACACGTGACCGTCACTATGGCCACGGCAGGCTGGGTCTAAAACCCTATCTCG
TGGTGGATACCGGCGGTTTTGAGCCTGTAGTCAAATCTGGCATCCTGCATGCCATGGCCAGACAAACCCTGCAGGCTGTA
GATGAGGCCGATGTTGTGCTGTTTATCGTCGATGGCCGTCAAGGACTGGCTTCACAAGACAAAATCATTGCAGATCAGCT
GCGTAAAACTGGCCGAAAAATAATACTCGTCGTCAATAAAGCCGAAGGGATGCCTTATTCAACAGCAGCAGTTGAATTCC
ATGAATTGGGACTGGGCACACCTTGTGTTGTTTCAGCTTTGCATGGAGAACATCTCGGTGAGCTGATTGATTTTGCACTG
GAAGATTATCCGTATGCAGAAGATATCGAAGCCGAGCCTGGTCAGGAAAAGCACCCCGTCATTGCCATTGCTGGCCGCCC
GAATGTTGGCAAATCCACACTGATCAATACACTTCTGGGTGAAGAGCGGATGATTGCCTTTGATCAACCAGGTACTACCA
GGGACAGTATTTATATTGATTTTGAATATGGCCAACGTCGCTATACATTGATCGATACGGCAGGTTTGCGCCGATCAGGC
AAGGTTTGGGAAACCGTGGAAAAATTCTCGGTGGTCAAGACCTTGCAATCGATCGAAGCTGCCAACGTGGTTGTCCTGGT
GCTGGATGCGCAAAGCGGTATCTCTGAACAGGATGCACATATTGCCGGATTCATACTGGAAACTGGTCGTGCACTGGTTA
TTGCAATCAACAAATGGGATGGCATGGATGACTACCAGCGTGATACCACCAAACGAGAGTTTGAACGCAAGCTTGCCTTT
CTGAATTTTGCTAACCTGCATTATATTTCCGCTCTGTACGGCAATGGAGTGAAAGCATTGATGCCTTCGGTTGATGCTGC
CTACACTGCAGCCATGGCGCATATCCCGACACCTAAGCTGACGCGCGTCATGTTGGCGGCTGTTGCCAAGCAACAGCCGC
CACGCGGTGGAGTATCACGGCCAAAACTGCGCTATGCGCACCAGGGAGGGGAAAACCCCCCACTGATTATTGTGCATGGC
TCGATGCTTGATCATGTTCCCCAAACCTATCGCCGCTATCTCGAAAATACCTTCAGAGACGTGTTCGAGTTAAAGGGCAC
TCCGCTGCGAGTGGAGTTCAGGACAGGCCATAATCCTTATGCTGGCAAAAAAGCGCCACCTTTGACCGAGGAAGAAGCGC
GACGCGCACATAGTCGTCGTCGTCGCAATCGCAAGAAATATGGTTGA

Upstream 100 bases:

>100_bases
TGTAGTACAAACACTCAAAGGCGGTGTTTTCGCTTTTTCCTTGCAATAACCGGATTTTTCTATGCTTTCCGGGTAAAGCA
TTTTTCATATCTCCTTTATC

Downstream 100 bases:

>100_bases
TTCCGAGAACAAGAACTTGCGTTAAACTTATTAAATTGTTCATGGCACCAACTAAGTTGAAGATATATCGTATACAAATA
TCTGTACAAGTTTTATTGGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKPTLVLVGRPNVGKSTLFNRLTRSRDAIVADIPGLTRDRHYGHGRLGLKPYLVVDTGGFEPVVKSGILHAMARQTLQAV
DEADVVLFIVDGRQGLASQDKIIADQLRKTGRKIILVVNKAEGMPYSTAAVEFHELGLGTPCVVSALHGEHLGELIDFAL
EDYPYAEDIEAEPGQEKHPVIAIAGRPNVGKSTLINTLLGEERMIAFDQPGTTRDSIYIDFEYGQRRYTLIDTAGLRRSG
KVWETVEKFSVVKTLQSIEAANVVVLVLDAQSGISEQDAHIAGFILETGRALVIAINKWDGMDDYQRDTTKREFERKLAF
LNFANLHYISALYGNGVKALMPSVDAAYTAAMAHIPTPKLTRVMLAAVAKQQPPRGGVSRPKLRYAHQGGENPPLIIVHG
SMLDHVPQTYRRYLENTFRDVFELKGTPLRVEFRTGHNPYAGKKAPPLTEEEARRAHSRRRRNRKKYG

Sequences:

>Translated_468_residues
MKPTLVLVGRPNVGKSTLFNRLTRSRDAIVADIPGLTRDRHYGHGRLGLKPYLVVDTGGFEPVVKSGILHAMARQTLQAV
DEADVVLFIVDGRQGLASQDKIIADQLRKTGRKIILVVNKAEGMPYSTAAVEFHELGLGTPCVVSALHGEHLGELIDFAL
EDYPYAEDIEAEPGQEKHPVIAIAGRPNVGKSTLINTLLGEERMIAFDQPGTTRDSIYIDFEYGQRRYTLIDTAGLRRSG
KVWETVEKFSVVKTLQSIEAANVVVLVLDAQSGISEQDAHIAGFILETGRALVIAINKWDGMDDYQRDTTKREFERKLAF
LNFANLHYISALYGNGVKALMPSVDAAYTAAMAHIPTPKLTRVMLAAVAKQQPPRGGVSRPKLRYAHQGGENPPLIIVHG
SMLDHVPQTYRRYLENTFRDVFELKGTPLRVEFRTGHNPYAGKKAPPLTEEEARRAHSRRRRNRKKYG
>Mature_468_residues
MKPTLVLVGRPNVGKSTLFNRLTRSRDAIVADIPGLTRDRHYGHGRLGLKPYLVVDTGGFEPVVKSGILHAMARQTLQAV
DEADVVLFIVDGRQGLASQDKIIADQLRKTGRKIILVVNKAEGMPYSTAAVEFHELGLGTPCVVSALHGEHLGELIDFAL
EDYPYAEDIEAEPGQEKHPVIAIAGRPNVGKSTLINTLLGEERMIAFDQPGTTRDSIYIDFEYGQRRYTLIDTAGLRRSG
KVWETVEKFSVVKTLQSIEAANVVVLVLDAQSGISEQDAHIAGFILETGRALVIAINKWDGMDDYQRDTTKREFERKLAF
LNFANLHYISALYGNGVKALMPSVDAAYTAAMAHIPTPKLTRVMLAAVAKQQPPRGGVSRPKLRYAHQGGENPPLIIVHG
SMLDHVPQTYRRYLENTFRDVFELKGTPLRVEFRTGHNPYAGKKAPPLTEEEARRAHSRRRRNRKKYG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=471, Percent_Identity=47.1337579617834, Blast_Score=437, Evalue=1e-123,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=39.1304347826087, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_NITEC (Q0AE46)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748351.1
- ProteinModelPortal:   Q0AE46
- SMR:   Q0AE46
- STRING:   Q0AE46
- GeneID:   4272813
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2164
- NMPDR:   fig|335283.3.peg.215
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- PhylomeDB:   Q0AE46
- ProtClustDB:   PRK00093
- BioCyc:   NEUT335283:NEUT_2164-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- SMART:   SM00382
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51989; Mature: 51989

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTLVLVGRPNVGKSTLFNRLTRSRDAIVADIPGLTRDRHYGHGRLGLKPYLVVDTGGF
CCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCC
EPVVKSGILHAMARQTLQAVDEADVVLFIVDGRQGLASQDKIIADQLRKTGRKIILVVNK
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEC
AEGMPYSTAAVEFHELGLGTPCVVSALHGEHLGELIDFALEDYPYAEDIEAEPGQEKHPV
CCCCCCCHHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
IAIAGRPNVGKSTLINTLLGEERMIAFDQPGTTRDSIYIDFEYGQRRYTLIDTAGLRRSG
EEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCEEEEEEECCCCCCCC
KVWETVEKFSVVKTLQSIEAANVVVLVLDAQSGISEQDAHIAGFILETGRALVIAINKWD
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEECCC
GMDDYQRDTTKREFERKLAFLNFANLHYISALYGNGVKALMPSVDAAYTAAMAHIPTPKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCHHH
TRVMLAAVAKQQPPRGGVSRPKLRYAHQGGENPPLIIVHGSMLDHVPQTYRRYLENTFRD
HHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
VFELKGTPLRVEFRTGHNPYAGKKAPPLTEEEARRAHSRRRRNRKKYG
HHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKPTLVLVGRPNVGKSTLFNRLTRSRDAIVADIPGLTRDRHYGHGRLGLKPYLVVDTGGF
CCCCEEEEECCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCEEEEEECCCC
EPVVKSGILHAMARQTLQAVDEADVVLFIVDGRQGLASQDKIIADQLRKTGRKIILVVNK
CHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEEC
AEGMPYSTAAVEFHELGLGTPCVVSALHGEHLGELIDFALEDYPYAEDIEAEPGQEKHPV
CCCCCCCHHHEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
IAIAGRPNVGKSTLINTLLGEERMIAFDQPGTTRDSIYIDFEYGQRRYTLIDTAGLRRSG
EEEECCCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCCEEEEEEECCCCCCCC
KVWETVEKFSVVKTLQSIEAANVVVLVLDAQSGISEQDAHIAGFILETGRALVIAINKWD
HHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEECCC
GMDDYQRDTTKREFERKLAFLNFANLHYISALYGNGVKALMPSVDAAYTAAMAHIPTPKL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCCHHH
TRVMLAAVAKQQPPRGGVSRPKLRYAHQGGENPPLIIVHGSMLDHVPQTYRRYLENTFRD
HHHHHHHHHHCCCCCCCCCCCCCHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHH
VFELKGTPLRVEFRTGHNPYAGKKAPPLTEEEARRAHSRRRRNRKKYG
HHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA