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The map label for this gene is fliN [H]

Identifier: 114332023

GI number: 114332023

Start: 2174860

End: 2175333

Strand: Direct

Name: fliN [H]

Synonym: Neut_2057

Alternate gene names: 114332023

Gene position: 2174860-2175333 (Clockwise)

Preceding gene: 114332022

Following gene: 114332024

Centisome position: 81.73

GC content: 50.63

Gene sequence:

>474_bases
ATGAATGAACCGATATCAACCGAACCACAAACCGAACAGGATGACTGGGCCGCCGCCATGGCGGAACAACAGGCTGCTGA
AACTTATTCGGTTATCGACGAAGCTAGCGAATCATCAGCCAGCGCATCGGCCCATATACCAGACGAGGATCTGACAAAGC
CATCTTCTGTTTTCGAGCAGTTTTCCAGGAATAATGTGCTGAACGATACCCGCAACGATATCGATATGATTCTGGATATT
CCGGTGCAACTGACAGTTGAGTTGGGTCGCACCCGAATCGCCATTAAAAATCTGCTGCAACTGGCACAAGGCTCCGTCAT
TGAGCTGGATGGCATGGCGGGCGAACCAATGGATGTGCTGGTCAATGGCTGCCTGATTGCCCAAGGTGAAGTCGTTGTCG
TCAATGAAAAATTTGGCATTCGCCTGACAGACATCATCACTCCCAGTGAACGCATCCGCAAACTGAACCGCTAG

Upstream 100 bases:

>100_bases
CATTACGGCATTCTCAACGATCACTATGCACTTAAAGTCAAGACTGTACGAACCCCAACTGAAACTGACTGATAATTAAA
ATCAAACATCGGAGCAGAAC

Downstream 100 bases:

>100_bases
CCCACCTCTGGATTGATTCCATACCCATGCCACGCATAATTGTCCAGATTGGCAGCATACTGTGGTTACCCCAACAGGTG
CTTGCTGAATCCGTGCGAAA

Product: flagellar motor switch protein FliN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MNEPISTEPQTEQDDWAAAMAEQQAAETYSVIDEASESSASASAHIPDEDLTKPSSVFEQFSRNNVLNDTRNDIDMILDI
PVQLTVELGRTRIAIKNLLQLAQGSVIELDGMAGEPMDVLVNGCLIAQGEVVVVNEKFGIRLTDIITPSERIRKLNR

Sequences:

>Translated_157_residues
MNEPISTEPQTEQDDWAAAMAEQQAAETYSVIDEASESSASASAHIPDEDLTKPSSVFEQFSRNNVLNDTRNDIDMILDI
PVQLTVELGRTRIAIKNLLQLAQGSVIELDGMAGEPMDVLVNGCLIAQGEVVVVNEKFGIRLTDIITPSERIRKLNR
>Mature_157_residues
MNEPISTEPQTEQDDWAAAMAEQQAAETYSVIDEASESSASASAHIPDEDLTKPSSVFEQFSRNNVLNDTRNDIDMILDI
PVQLTVELGRTRIAIKNLLQLAQGSVIELDGMAGEPMDVLVNGCLIAQGEVVVVNEKFGIRLTDIITPSERIRKLNR

Specific function: FliN is one of three proteins (FliG, FliN, FliM) that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor

COG id: COG1886

COG function: function code NU; Flagellar motor switch/type III secretory pathway protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliN/MopA/SpaO family [H]

Homologues:

Organism=Escherichia coli, GI1788256, Length=157, Percent_Identity=52.2292993630573, Blast_Score=153, Evalue=5e-39,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012826
- InterPro:   IPR001172
- InterPro:   IPR001543 [H]

Pfam domain/function: PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 17240; Mature: 17240

Theoretical pI: Translated: 4.00; Mature: 4.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEPISTEPQTEQDDWAAAMAEQQAAETYSVIDEASESSASASAHIPDEDLTKPSSVFEQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHH
FSRNNVLNDTRNDIDMILDIPVQLTVELGRTRIAIKNLLQLAQGSVIELDGMAGEPMDVL
HHCCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHH
VNGCLIAQGEVVVVNEKFGIRLTDIITPSERIRKLNR
HCCEEEECCCEEEEECCCCEEEEEECCCHHHHHHCCC
>Mature Secondary Structure
MNEPISTEPQTEQDDWAAAMAEQQAAETYSVIDEASESSASASAHIPDEDLTKPSSVFEQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCHHHHHHH
FSRNNVLNDTRNDIDMILDIPVQLTVELGRTRIAIKNLLQLAQGSVIELDGMAGEPMDVL
HHCCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCCCHHHH
VNGCLIAQGEVVVVNEKFGIRLTDIITPSERIRKLNR
HCCEEEECCCEEEEECCCCEEEEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2651416; 9097040; 9278503 [H]