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The map label for this gene is fliM [H]

Identifier: 114332022

GI number: 114332022

Start: 2173839

End: 2174831

Strand: Direct

Name: fliM [H]

Synonym: Neut_2056

Alternate gene names: 114332022

Gene position: 2173839-2174831 (Clockwise)

Preceding gene: 114332021

Following gene: 114332023

Centisome position: 81.69

GC content: 48.04

Gene sequence:

>993_bases
ATGGCCGAGAATTTTCTCACTCAGGATGAAGTTGATGCGCTACTGAATTTTGATAACAGTAACAAGCATCAGCAAGCAGC
CCAGAAGGAAAACGGGGTTACCTATCCGGGCGGTATCCGTCCTTACGACATGGCCACCCAGGAGCGGATTGTGCGGGGAC
GCATGCCCGCTCTGGAAATTATCAATGCACGCTTTGCCAATTCTCTGCAGATTGGGCTCTACAATTTTTTACGCCGGGGG
GTAGATATTTCCGCTGGCTCAATAAAAACCATCAAATACAGCGAATTCACCCGTTCGCTGGTCGTGCCTGCAAATATCAA
CATGGTCAGCATGAAACCATTGCGCGGCACTGCACTGATCACCATTGATCCGAACCTGATATTTCTGATCGTGGACAATA
TGTTCGGTGGAGATGGTCGTTTTCATACCCGAGTGGAAGGACGTGAGTTCACCCTGACCGAACAGGGCATTATCCGACGC
TTGCTGGATGTTTTATTCGAAAACTACGAGAAAGCCTGGAAATCTGTCTACCCGGTCAGATTTGAATACATCCGTGCGGA
AATGAATCCGCAATTTGCCAATATTGCGACACCAACCGATGTTGTTGTTGCAAGCTCGTTTGAGCTCAATCTGGGCGGTA
ATCGTGGAGAGTTCTACATCTGCACCCCCTACACCATGCTGGAGCCAATACGTGATCTGCTCAACAACAGCATGCAGGAA
GATCATGCAGAAGTTGATAATAACTGGATCAAGTCGCTAACCAGACAGGTACAAGGCGCAGAAATAGAAATTATTGCTAA
TCTCGGCCATACCCGGGTGACGTTACACCAGATCCTCAACATGCAGGAAGGCGATGTCATCGCACTCGATATTCCGGACA
CAGTAGTTGCTATGGCAAATGGTGTACCGATCATGGATTGTCATTACGGCATTCTCAACGATCACTATGCACTTAAAGTC
AAGACTGTACGAACCCCAACTGAAACTGACTGA

Upstream 100 bases:

>100_bases
CATTCAGGCGATCCGATCAAAGATTGGATCTGAAGCCCTGCAAAATGACATTCTGGATGTTTTGTTCACCTCTTTCATTA
TTCAGTAAACCCTGCGCGCC

Downstream 100 bases:

>100_bases
TAATTAAAATCAAACATCGGAGCAGAACATGAATGAACCGATATCAACCGAACCACAAACCGAACAGGATGACTGGGCCG
CCGCCATGGCGGAACAACAG

Product: flagellar motor switch protein FliM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MAENFLTQDEVDALLNFDNSNKHQQAAQKENGVTYPGGIRPYDMATQERIVRGRMPALEIINARFANSLQIGLYNFLRRG
VDISAGSIKTIKYSEFTRSLVVPANINMVSMKPLRGTALITIDPNLIFLIVDNMFGGDGRFHTRVEGREFTLTEQGIIRR
LLDVLFENYEKAWKSVYPVRFEYIRAEMNPQFANIATPTDVVVASSFELNLGGNRGEFYICTPYTMLEPIRDLLNNSMQE
DHAEVDNNWIKSLTRQVQGAEIEIIANLGHTRVTLHQILNMQEGDVIALDIPDTVVAMANGVPIMDCHYGILNDHYALKV
KTVRTPTETD

Sequences:

>Translated_330_residues
MAENFLTQDEVDALLNFDNSNKHQQAAQKENGVTYPGGIRPYDMATQERIVRGRMPALEIINARFANSLQIGLYNFLRRG
VDISAGSIKTIKYSEFTRSLVVPANINMVSMKPLRGTALITIDPNLIFLIVDNMFGGDGRFHTRVEGREFTLTEQGIIRR
LLDVLFENYEKAWKSVYPVRFEYIRAEMNPQFANIATPTDVVVASSFELNLGGNRGEFYICTPYTMLEPIRDLLNNSMQE
DHAEVDNNWIKSLTRQVQGAEIEIIANLGHTRVTLHQILNMQEGDVIALDIPDTVVAMANGVPIMDCHYGILNDHYALKV
KTVRTPTETD
>Mature_329_residues
AENFLTQDEVDALLNFDNSNKHQQAAQKENGVTYPGGIRPYDMATQERIVRGRMPALEIINARFANSLQIGLYNFLRRGV
DISAGSIKTIKYSEFTRSLVVPANINMVSMKPLRGTALITIDPNLIFLIVDNMFGGDGRFHTRVEGREFTLTEQGIIRRL
LDVLFENYEKAWKSVYPVRFEYIRAEMNPQFANIATPTDVVVASSFELNLGGNRGEFYICTPYTMLEPIRDLLNNSMQED
HAEVDNNWIKSLTRQVQGAEIEIIANLGHTRVTLHQILNMQEGDVIALDIPDTVVAMANGVPIMDCHYGILNDHYALKVK
TVRTPTETD

Specific function: FliM is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the mot

COG id: COG1868

COG function: function code N; Flagellar motor switch protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Bacterial flagellum basal body [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FliM family [H]

Homologues:

Organism=Escherichia coli, GI1788255, Length=327, Percent_Identity=46.7889908256881, Blast_Score=322, Evalue=1e-89,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001689
- InterPro:   IPR001543 [H]

Pfam domain/function: PF02154 FliM; PF01052 SpoA [H]

EC number: NA

Molecular weight: Translated: 37272; Mature: 37141

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENFLTQDEVDALLNFDNSNKHQQAAQKENGVTYPGGIRPYDMATQERIVRGRMPALEI
CCCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
INARFANSLQIGLYNFLRRGVDISAGSIKTIKYSEFTRSLVVPANINMVSMKPLRGTALI
HHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEHHHHCEEEECCCCCEEEECCCCCEEEE
TIDPNLIFLIVDNMFGGDGRFHTRVEGREFTLTEQGIIRRLLDVLFENYEKAWKSVYPVR
EECCCEEEEEEECCCCCCCEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEE
FEYIRAEMNPQFANIATPTDVVVASSFELNLGGNRGEFYICTPYTMLEPIRDLLNNSMQE
EEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCHHHH
DHAEVDNNWIKSLTRQVQGAEIEIIANLGHTRVTLHQILNMQEGDVIALDIPDTVVAMAN
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHC
GVPIMDCHYGILNDHYALKVKTVRTPTETD
CCEEEEECCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure 
AENFLTQDEVDALLNFDNSNKHQQAAQKENGVTYPGGIRPYDMATQERIVRGRMPALEI
CCCCCCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCHHHH
INARFANSLQIGLYNFLRRGVDISAGSIKTIKYSEFTRSLVVPANINMVSMKPLRGTALI
HHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEHHHHCEEEECCCCCEEEECCCCCEEEE
TIDPNLIFLIVDNMFGGDGRFHTRVEGREFTLTEQGIIRRLLDVLFENYEKAWKSVYPVR
EECCCEEEEEEECCCCCCCEEEEEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCEE
FEYIRAEMNPQFANIATPTDVVVASSFELNLGGNRGEFYICTPYTMLEPIRDLLNNSMQE
EEEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCHHHH
DHAEVDNNWIKSLTRQVQGAEIEIIANLGHTRVTLHQILNMQEGDVIALDIPDTVVAMAN
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHC
GVPIMDCHYGILNDHYALKVKTVRTPTETD
CCEEEEECCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3519573; 9097040; 9278503; 2651416 [H]