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The map label for this gene is tsf

Identifier: 114332000

GI number: 114332000

Start: 2149892

End: 2150776

Strand: Reverse

Name: tsf

Synonym: Neut_2034

Alternate gene names: 114332000

Gene position: 2150776-2149892 (Counterclockwise)

Preceding gene: 114332001

Following gene: 114331999

Centisome position: 80.82

GC content: 45.54

Gene sequence:

>885_bases
ATGGCAGAGATTACTGCAAGCATGGTTAAAGAATTGCGCGAGCTTACCGGCTTGGGCATGATGGAATGTAAAAAAGCCTT
ATCCGAGGCTGGTGGAGATATGAAAGCCGCTGAGGATTTATTGCGGATCAGAAGTGGAGCCAAAGCAAGTAAAGCGGCTG
CTCGTATTGCTGCAGAAGGAGTTATTAGCGGATTTATTACCGTTGATGGCAAACAGGGAGCGCTGATAGAGGTTAACTGT
GAAACCGACTTTGTTGCCAAGAATGAAGATTTCATCAATTTTGCCGGCGATCTGGCGAAGCTGATGGTGAGTCAAAGTGT
TTCAGATACAGCATTATTGGCTGAAATGCCTCTGGCTGGTGGAGAAACGGTTGAATCTGTTCGCAAGGCTTTGATTATGA
AGCTGGGCGAAAATATTAGTATTCGTCGTGGGATCAGTTACCATGCCGAAGGTCGTCTCGCGATGTATCTACACGGGAGC
AGGATCGGTGTAATGGTTGATTATTCGGGGGGAGACGAAGCCTTGGGTAAAGATATAGCCATGCATATTGCGGCCAGCAA
GCCTGTTTGCGTATCAAGTGCACAAGTCCCCGTTGATTTACTTGAGCATGAGCGTCAGATATTTACTGCCCAGGCAGCAG
AAAGTGGCAAACCGGCTAATATAATTGAGAAAATGGTGGAAGGGCGAGTTACCAAATATTTGGCAGAAGTTACATTGTTA
GGCCAGCCTTTTGTTAAAGATCCCGAGCAGACTGTTGAGAAGCTGTTAAAAACAAAATCTGCTGAAGTCAGCAATTTTAC
ACTGTACGTTGTAGGTGAGGGAATCGAAAGGAAATCTGATGATTTTGCAGCTGAGGTTATGGCGCAGGTAAGTCAGTCAA
AATAA

Upstream 100 bases:

>100_bases
TGGTCAAGATCTGTCTGCAGATGCATAAATGATCTCCGTTACCACCTCTTATTGAAATAGATTATTCAAAGTTTTTGTAT
TAACCGGATCCGGAGTCAGT

Downstream 100 bases:

>100_bases
GAATGTTTTCCAGCGATTGGTTTGACCGGGCATGTGGCAGAGGTAAATGATAACTTATCACTATAAGCTAGGATCTGTTG
AGATTCAGTATCTGGTGTAG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAEITASMVKELRELTGLGMMECKKALSEAGGDMKAAEDLLRIRSGAKASKAAARIAAEGVISGFITVDGKQGALIEVNC
ETDFVAKNEDFINFAGDLAKLMVSQSVSDTALLAEMPLAGGETVESVRKALIMKLGENISIRRGISYHAEGRLAMYLHGS
RIGVMVDYSGGDEALGKDIAMHIAASKPVCVSSAQVPVDLLEHERQIFTAQAAESGKPANIIEKMVEGRVTKYLAEVTLL
GQPFVKDPEQTVEKLLKTKSAEVSNFTLYVVGEGIERKSDDFAAEVMAQVSQSK

Sequences:

>Translated_294_residues
MAEITASMVKELRELTGLGMMECKKALSEAGGDMKAAEDLLRIRSGAKASKAAARIAAEGVISGFITVDGKQGALIEVNC
ETDFVAKNEDFINFAGDLAKLMVSQSVSDTALLAEMPLAGGETVESVRKALIMKLGENISIRRGISYHAEGRLAMYLHGS
RIGVMVDYSGGDEALGKDIAMHIAASKPVCVSSAQVPVDLLEHERQIFTAQAAESGKPANIIEKMVEGRVTKYLAEVTLL
GQPFVKDPEQTVEKLLKTKSAEVSNFTLYVVGEGIERKSDDFAAEVMAQVSQSK
>Mature_293_residues
AEITASMVKELRELTGLGMMECKKALSEAGGDMKAAEDLLRIRSGAKASKAAARIAAEGVISGFITVDGKQGALIEVNCE
TDFVAKNEDFINFAGDLAKLMVSQSVSDTALLAEMPLAGGETVESVRKALIMKLGENISIRRGISYHAEGRLAMYLHGSR
IGVMVDYSGGDEALGKDIAMHIAASKPVCVSSAQVPVDLLEHERQIFTAQAAESGKPANIIEKMVEGRVTKYLAEVTLLG
QPFVKDPEQTVEKLLKTKSAEVSNFTLYVVGEGIERKSDDFAAEVMAQVSQSK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=286, Percent_Identity=28.3216783216783, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786366, Length=293, Percent_Identity=48.8054607508532, Blast_Score=251, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI17561440, Length=291, Percent_Identity=28.1786941580756, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921466, Length=292, Percent_Identity=28.0821917808219, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_NITEC (Q0AEH5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748222.1
- STRING:   Q0AEH5
- GeneID:   4273246
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2034
- NMPDR:   fig|335283.3.peg.2495
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q0AEH5
- ProtClustDB:   PRK09377
- BioCyc:   NEUT335283:NEUT_2034-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 31446; Mature: 31314

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEITASMVKELRELTGLGMMECKKALSEAGGDMKAAEDLLRIRSGAKASKAAARIAAEG
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
VISGFITVDGKQGALIEVNCETDFVAKNEDFINFAGDLAKLMVSQSVSDTALLAEMPLAG
HHEEEEEEECCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
GETVESVRKALIMKLGENISIRRGISYHAEGRLAMYLHGSRIGVMVDYSGGDEALGKDIA
CHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEECCEEEEEEEECCCCHHHHHHHH
MHIAASKPVCVSSAQVPVDLLEHERQIFTAQAAESGKPANIIEKMVEGRVTKYLAEVTLL
EEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GQPFVKDPEQTVEKLLKTKSAEVSNFTLYVVGEGIERKSDDFAAEVMAQVSQSK
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEITASMVKELRELTGLGMMECKKALSEAGGDMKAAEDLLRIRSGAKASKAAARIAAEG
CCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
VISGFITVDGKQGALIEVNCETDFVAKNEDFINFAGDLAKLMVSQSVSDTALLAEMPLAG
HHEEEEEEECCCCCEEEEECCCCEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
GETVESVRKALIMKLGENISIRRGISYHAEGRLAMYLHGSRIGVMVDYSGGDEALGKDIA
CHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEECCEEEEEEEECCCCHHHHHHHH
MHIAASKPVCVSSAQVPVDLLEHERQIFTAQAAESGKPANIIEKMVEGRVTKYLAEVTLL
EEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GQPFVKDPEQTVEKLLKTKSAEVSNFTLYVVGEGIERKSDDFAAEVMAQVSQSK
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA